Immunogenicity, breakthrough infection, and underlying disease flare after SARS-CoV-2 vaccination among individuals with systemic autoimmune rheumatic diseases전신 자가면역 류마티스 질환이 있는 개인에서 SARS-CoV-2 백신 접종 후 면역원성, 돌발성 감염 및 기저 질환 발적Review Published on 2022-08-012022-09-12 Journal: Current opinion in pharmacology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome Autoimmune Breakthrough infection clinical trial coronavirus detrimental disease Disease activity doses humoral immunogenicity immune response immunogenicity Immunosuppressed Immunosuppression Impact include individual Patient reduce rheumatic disease SARS-CoV-2 SARS-CoV-2 vaccination severity underlying disease vaccination Vaccine waning immunity [DOI] 10.1016/j.coph.2022.102243 PMC 바로가기 [Article Type] Review
Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies회복기 및 백신 혈청 및 단일 클론 항체에 의한 SARS-CoV-2 오미크론 하위 변이체 BA.1 및 BA.2의 제한된 중화Article Published on 2022-08-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 addition antibody BA.1 BA.2 BNT162b2 booster booster dose booster vaccination breakthrough infections Casirivimab Cell Complete convalescent convalescent sera Delta dominant dose education Efficacy elicited exhibited expressing Frankfurt Imdevimab Immunity in vitro study individual infection with SARS-CoV-2 Limited majority median monoclonal antibodies monoclonal antibody monoclonal antibody therapy Mutation neutralisation neutralise neutralising neutralizing capacity omicron Omicron variants reduced Region SARS-CoV-2 sera serum Sotrovimab specific resistance Spike protein supported tested the SARS-CoV-2 the spike protein therapy TMPRSS2 university vaccination Vaccine Vaccines variants variants of SARS-CoV-2 waning immunity [DOI] 10.1016/j.ebiom.2022.104158 PMC 바로가기 [Article Type] Article
Detection of neutralizing antibodies against multiple SARS-CoV-2 strains in dried blood spots using cell-free PCRCell-free PCR을 이용한 건조된 혈반에서 여러 SARS-CoV-2 균주에 대한 중화항체 검출Article Published on 2022-07-212022-09-11 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age angiotensin binding conditions coronavirus detect detection dried blood spot Dried blood spots Efficacy Health help herd immunity human Angiotensin-converting enzyme Immunity inhibition multiplex Neutralization assay Neutralizing antibodies neutralizing antibody PCR real-time qPCR receptor protein respiratory SARS-CoV-2 SARS-CoV-2 strain sensitivity Serological assay serum severe acute respiratory syndrome Coronavirus specificity specimen Spike protein subunit vaccination vaccination rates Vaccine vaccine efficacy Viral viral spike protein waning immunity [DOI] 10.1038/s41467-022-31796-1 PMC 바로가기 [Article Type] Article
SARS-CoV-2 testing strategies for outbreak mitigation in vaccinated populations백신 접종 집단의 발병 완화를 위한 SARS-CoV-2 테스트 전략Article Published on 2022-07-132022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] approach assays chain Chain Reaction country Coverage COVID-19 outbreak COVID-19 vaccine COVID-19 vaccines disease effective epidemiological example Frequency help identify India individual International mitigate outbreak polymerase chain reaction Population Rapid antigen tests reaction reduce reducing reverse transcriptase Reverse transcriptase polymerase chain reaction RT-PCR SARS-CoV-2 SARS-CoV-2 testing Spread subsequent sustained Testing The United States transition Transmission United States vaccination Vaccination strategy Vaccinations Variability variants of concern waning immunity [DOI] 10.1371/journal.pone.0271103 PMC 바로가기 [Article Type] Article
Immunogenicity and Reactogenicity of Ad26.COV2.S in Korean Adults: A Prospective Cohort Study한국 성인에서 Ad26.COV2.S의 면역원성과 반응성: 전향적 코호트 연구Article Published on 2022-07-112022-09-11 Journal: Journal of Korean medical science [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ad26 Ad26.COV2.S Adenovirus Adenovirus Vector Adverse adverse event adverse events AEs anti-S IgG Anti-spike baseline cellular immunity conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 decrease Delta Dilution enrolled enzyme enzyme-linked immunospot assay evaluated fatigue Fever followed by geometric mean geometric mean titers GMT GMTs GRADE Humoral immunity IgG antibody immunogenic immunogenicity injection site pain interferon interferon-γ Korean mononuclear cell MOST myalgia NAb titer Neutralizing Neutralizing activity neutralizing antibody responses omicron Omicron variant Omicron variants outcome pandemic participant Peripheral blood Prospective prospective cohort study resolved respiratory Safe SARS-CoV-2 serious AEs severe acute respiratory syndrome Coronavirus Single-dose South Korea T-cell immunity T-cell Response T-cell responses the median U/mL university hospital vaccination Vaccines variant variants Viral Viral variants waning immunity wild-type WT SARS-CoV-2 [DOI] 10.3346/jkms.2022.37.e210 PMC 바로가기 [Article Type] Article
Vaccination and variants: Retrospective model for the evolution of Covid-19 in Italy예방 접종 및 변종: 이탈리아의 Covid-19 진화에 대한 회고 모델Article Published on 2022-07-082022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] absence appearance changes characterized combined effect compartmental model contagious COVID-19 pandemic deaths decreases delta variant develop dominant effective Effects epidemiological Evolution followed by individual induce Infection Italy measure mechanism mechanisms normality omicron Omicron variant pandemic Particular predict Retrospective analysis seasonal variation stability vaccination Vaccine Variability variant Variation virus virus infectivity waning immunity [DOI] 10.1371/journal.pone.0265159 PMC 바로가기 [Article Type] Article
Protection of hamsters challenged with SARS-CoV-2 after two doses of MVC-COV1901 vaccine followed by a single intranasal booster with nanoemulsion adjuvanted S-2P vaccineMVC-COV1901 백신 2회 접종 후 SARS-CoV-2에 감염된 햄스터 보호 및 나노에멀젼 보조제 S-2P 백신이 포함된 단일 비강 내 부스터Article Published on 2022-07-052022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] alum booster booster vaccination country COVID-19 COVID-19 vaccine COVID-19 vaccines CpG1018 death Delta disease dose elicit followed by hamster Hospitalization Immunity immunization immunogenicity Infection intramuscular intranasal Lung pathology medical need mucosal offer omicron Pandemics Patient prefusion problem promote protection protective immunity protocol reduced regimen respiratory respiratory tracts resurgence robust S-2P SARS-CoV-2 SARS-CoV-2 spike severe COVID-19 severe disease solution Transmission vaccination Vaccine variants variants of SARS-CoV-2 Viral viral challenge viral clearance viral infection waning immunity weight loss were used [DOI] 10.1038/s41598-022-15238-y PMC 바로가기 [Article Type] Article
Characterization of the significant decline in humoral immune response six months post-SARS-CoV-2 mRNA vaccination: A systematic reviewSARS-CoV-2 mRNA 백신 접종 후 6개월 후 체액성 면역 반응의 현저한 감소 특성: 체계적인 검토Review Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration age anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-Spike IgG antibody Antibody Response Antibody titer Antibody titers appearance article binding domain BNT161b2 BNT162b2 booster Breakthrough infection breakthrough infections calculated characterization Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mRNA Vaccination determine Effect Efficacy Evidence exhibited Factor finding highlight humoral humoral immune response Humoral immunity Humoral response IgG Immunoglobulin Immunoglobulin G independent independent of Kinetics Longitudinal data Messenger RNA Moderna mRNA mRNA 1273 mRNA BNT162b2 mRNA vaccination mRNA-1273 Participants peak levels Pfizer-BioNTech postvaccination presence of comorbidities reached reported respiratory second dose serostatus Serum level serum levels severe acute respiratory syndrome Coronavirus Sex systematic review Vaccination strategy Vaccine Vaccines variant waning immunity was performed [DOI] 10.1002/jmv.27688 PMC 바로가기 [Article Type] Review
Evaluation of antibody titer kinetics and SARS-CoV-2 infections in a large cohort of healthcare professionals ten months after administration of the BNT162b2 vaccineBNT162b2 백신 투여 10개월 후 대규모 의료 전문가 집단에서 항체 역가 동역학 및 SARS-CoV-2 감염 평가Multicenter Study Published on 2022-07-012022-09-11 Journal: Journal of Immunological Methods [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] administration Anti-spike antibody Antibody Response Antibody titer BNT162b2 BNT162b2 vaccine booster dose Coverage COVID-19 COVID-19 vaccine decrease detectable difference dose Efficacy first dose follow-up period hcp Healthcare professional humoral Humoral response immune response Infection large cohort median titer mRNA vaccine multicenter multicenter study occurred population studies Post-vaccination infection Prevalence receiving Receptor-binding domain Roche Roche anti-SARS-CoV-2-S SARS-COV-2 infection SARS-CoV-2 infections serological test seronegative seronegatives seropositive serum serum antibody shown Spike protein Symptomatology the antibody response the median the receptor-binding domain the SARS-CoV-2 the spike protein time interval time intervals vaccination Vaccination strategy Vaccine vaccine efficacy vaccine response waning immunity was tested were measured within 6 months [DOI] 10.1016/j.jim.2022.113293 PMC 바로가기 [Article Type] Multicenter Study
Investigating COVID-19 Vaccine Impact on the Risk of Hospitalisation through the Analysis of National Surveillance Data Collected in Belgium벨기에에서 수집된 국가 감시 데이터 분석을 통한 코로나19 백신이 입원 위험에 미치는 영향 조사Article Published on 2022-06-162022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] absence Administered age analysed Belgium booster vaccination category Comorbidities COVID-19 COVID-19 hospitalisation COVID-19 patient dominance Evolution Factor hospitalisation hospitalisation surveillance hospitalised Impact infections National omicron Omicron variant Probability receive risk risk of COVID-19 risk ratio risk ratios SARS-CoV-2 SARS-COV-2 infection stratified surveillance data vaccination Vaccination impact Vaccination Status Vaccine variant waning immunity [DOI] 10.3390/v14061315 PMC 바로가기 [Article Type] Article