An Update on COVID-19 Vaccine Induced Thrombotic Thrombocytopenia Syndrome and Some Management RecommendationsReview Published on 2021-08-182022-10-30 Journal: Molecules [Category] COVID-19, [키워드] absence Adenovirus-vectored vaccine Affect appear AstraZeneca bleeding characterized complication of COVID-19 country COVID-19 COVID-19 disease COVID-19 vaccine Disseminated intravascular coagulation events female fibrinogen level heparin induced thrombocytopenia heparin-induced thrombocytopenia individuals induced Ischemia mass vaccination occur Patient Platelet platelet factor 4 risk risk factor syndrome thrombocytopenia thrombosis thrombotic thrombotic thrombo-cytopenic purpura Treatment Vaccine vaccine induced thrombocytopenia and thrombosis Vaccines venous venous thromboembolic worsening younger patient [DOI] 10.3390/molecules26165004 PMC 바로가기 [Article Type] Review
Has COVID-19 lockdown improved glycaemic control in pediatric patients with type 1 diabetes? An analysis of continuous glucose monitoring metricsObservational Study Published on 2021-08-012022-10-05 Journal: Diabetes research and clinical practice [Category] 임상, [키워드] Adolescence age ambulatory Ambulatory glucose profile analysed Analysis children Clinical data Cohort collected COVID-19 demographic diabete disease enrolled evaluate Glucose glycaemic control hybrid Hybrid closed loop IMPROVE individual insulin Interaction lockdown management Metrics outcome paediatric patient pandemic Patient patients Pediatric patient statistically study population T1D therapy time Time in range. Treatment Variation younger patient [DOI] 10.1016/j.diabres.2021.108988 PMC 바로가기 [Article Type] Observational Study
Differential Association of Viral Dynamics With Disease Severity Depending on Patients’ Age Group in COVID-19Microbiology Published on 2021-07-232022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute phase addition age antiviral drug association C-reactive protein Clinical severity Cohort collected COVID-19 COVID-19 patient critical cases Critical disease detectable disease severity distribution Dynamics Elderly patient elderly patients explain fatality group IL-6 Infection Inflammation Inflammatory responses Intervention investigated lactate dehydrogenase Mild mild case mitigate neutralizing antibody not significantly different Patient plasma positive correlation reduce required respiratory specimen SARS-CoV-2 severe disease progression severity severity of COVID-19 therapeutic therapy viral burden Viral load with COVID-19 younger patient [DOI] 10.3389/fmicb.2021.712260 PMC 바로가기 [Article Type] Microbiology
Spatial epidemiological study of the distribution, clustering, and risk factors associated with early COVID-19 mortality in MexicoResearch Article Published on 2021-07-212022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] age Analysis association caused chronic respiratory diseases Clustering conditions Course COVID-19 COVID-19 mortality COVID-19 outbreak COVID-19 pandemic diabete diabetes Diseases distribution epidemiological Epidemiological study evaluate expected fatality Healthcare system highest hypertension Immunosuppression impacted individual Medical conditions Migration Mortality mortality risk obesity Older percentage positive predictor Quintana Roo Respiratory disease risk risk factor SARS-CoV-2 severity significantly tested the disease variables with COVID-19 younger patient zone [DOI] 10.1371/journal.pone.0254884 PMC 바로가기 [Article Type] Research Article
Target Groups for a Short Dexamethasone Course among Critically Ill COVID-19 PatientsResearch Article Published on 2021-07-162022-10-31 Journal: Critical Care Research and Practice [Category] COVID-19, [키워드] 28-day mortality 95% confidence interval administration adverse event Analysis assigned Bacterial infection benefit category Cohort collected conducted coronavirus disease Course COVID-19 COVID-19 patient COVID-19 patients Critically ill Critically ill patient database decrease determine Dexamethasone died evaluate female group highest hyperglycemia ICU ICU admission Ill IMV intensive care Invasive mechanical ventilation management median Mortality Older outcome Patient patient subgroup patients Population Primary outcome receiving reduce regimen Result retrospective cohort study Septic shock significantly significantly higher significantly lower significantly more single-center steroid subgroup analysis target therapeutic agent treated usual care usual care groups was performed younger patient younger patients [DOI] 10.1155/2021/5557302 PMC 바로가기 [Article Type] Research Article
Demographic and clinical characteristics of severe Covid-19 infections: a cross-sectional study from Mashhad University of Medical Sciences, Iran심각한 Covid-19 감염의 인구 통계 학적 및 임상 특성 :이란 Mashhad Medical Sciences University의 단면 연구Research Article Published on 2021-07-072022-09-10 Journal: BMC Infectious Diseases [Category] SARS, 치료제, [키워드] age Antibiotic therapy Antiviral cardiovascular disorder Cardiovascular disorders Characteristics Clinical characteristics Clinical data clinical symptom Clinical symptoms co-morbidities co-morbidity coronavirus disease Coronavirus disease 2019 cough country COVID-19 infections COVID-19, SARS-COV-2 cross-sectional demographic demographic and clinical characteristics diabete diabetes died disease duration of hospitalization Dyspnoea Epidemiological characteristics fatality Fever groups Healthcare workers infected patient infected patients Infection IQR Iran Logistic regression analysis Mashhad median Medical Sciences morbidities multivariate multivariate logistic regression analysis Odds ratio outcome Patient positive prevalent respiratory Result severe COVID-19 specimens supplementary material survivor Survivors Symptoms, Iran university upper respiratory was used younger patient younger patients [DOI] 10.1186/s12879-021-06363-6 PMC 바로가기 [Article Type] Research Article
Incidence of SARS-CoV-2 in people with cystic fibrosis in Europe between February and June 2020Observational Study Published on 2021-07-012022-10-05 Journal: Journal of cystic fibrosis : official journal of t [Category] 임상, [키워드] age all age group available data coronavirus 2 country COVID-19 Cystic cystic fibrosis death died Epidemiology Europe European Fatality rate fibrosis General population group Health hospital incidence Infection intensive care lung transplant morbidity MOST pandemic Patient rates of admission recipients registry reported respiratory SARS-CoV-2 SARS-COV-2 infection significantly higher Society statistically significant vaccination yielding younger patient [DOI] 10.1016/j.jcf.2021.03.017 PMC 바로가기 [Article Type] Observational Study
The effects of home confinement on pediatric fractures during the COVID 19 outbreakResearch Published on 2021-06-302022-10-29 Journal: Italian Journal of Pediatrics [Category] Coronavirus, MERS, SARS, [키워드] age children Chinese Chongqing coronavirus disease COVID 19 COVID-19 COVID-19 outbreak Effect Epidemiology etiology evaluate the effect Government home home confinement Home isolation Injury male objective Occurrence outbreak Patient pediatric Pediatric fractures Perspective proportion reached reduction in Result screened Sex Transmission university younger patient [DOI] 10.1186/s13052-021-01092-7 PMC 바로가기 [Article Type] Research
Disentangling the Association of Hydroxychloroquine Treatment with Mortality in Covid-19 Hospitalized Patients through Hierarchical ClusteringResearch Article Published on 2021-06-252022-10-31 Journal: Journal of Healthcare Engineering [Category] COVID-19, MERS, SARS, [키워드] adjusted age association Blood Cancer carried Characteristics chronic pulmonary diseases circulating Cluster Clustering Clusters collected contribute death diabetes disease severity driven by Effect Efficacy Gower distance HCQ Hierarchical Hydroxychloroquine identify independent Inflammation Interaction Italy medication men Modification Mortality multivariable obesity Older outcome parameters Patient patients patients hospitalized regressions renal function retrospective risk Sex Smokers smoking status subjects subtype survived tested treating SARS-CoV-2 infection Treatment were used younger patient [DOI] 10.1155/2021/5556207 PMC 바로가기 [Article Type] Research Article
PNPLA3 and TLL-1 Polymorphisms as Potential Predictors of Disease Severity in Patients With COVID-19Cell and Developmental Biology Published on 2021-06-232022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] 95% CI absence ACE2 Admission Affect angiotensin-converting enzyme 2 binding characterized cleavage site Clinical course Comorbidity consecutive patient contribute Course COVID-19 death determinant disease course early phase Genetic polymorphism Genetic variant Genotype higher risk host cell host gene host receptor host’s cells IFNL3 immune stimulation in silico increased risk infect Infection Inflammation Intensive involved MERTK Mild nasopharyngeal swabs NLRP3 inflammasome nucleic acid older patient outcome pandemic Pathogenesis pathogenesis of COVID-19 pathway Patient PNPLA3 PNPLA3 I148M polymorphism Potential predicted Predictive Prognosis protease Protease activity Protein protein cleavage re-infect Reinfection risk SARS-CoV-2 SARS-COV-2 infection Severity of disease Sex significantly Specific spike subject subsequent Support the SARS-CoV-2 the Spike therapeutic approaches therapy tissue damage TLL-1 upregulation variant were assessed younger patient [DOI] 10.3389/fcell.2021.627914 PMC 바로가기 [Article Type] Cell and Developmental Biology