Death after the Administration of COVID-19 Vaccines Approved by EMA: Has a Causal Relationship Been Demonstrated?Review Published on 2022-02-162022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Administered benefit carried Causal causal link cause clinical trial COVID-19 COVID-19 vaccination COVID-19 vaccine death dose eight events excluded highlight immune literature review Myocardial infarction myocarditis pathophysiological mechanism Post-mortem relationship reported risk SARS-CoV-2 Scientific community Side effects Spread Surveillance the vaccine thrombotic vaccination Vaccine [DOI] 10.3390/vaccines10020308 PMC 바로가기 [Article Type] Review
Implication of COVID-19 on Erythrocytes Functionality: Red Blood Cell Biochemical Implications and Morpho-Functional Aspects적혈구 기능에 대한 COVID-19의 의미: 적혈구 생화학적 의미 및 형태-기능적 측면Review Published on 2022-02-162022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, 치료제, [키워드] Affect alteration Anemia antioxidant aspect Blood blood cell Blood cells Cancer cause causes Cell change changes changes in Concentration Course COVID COVID-19 COVID-19 severity diabetes disease disease severity distribution enzyme erythrocyte erythrocytes evaluated focus help hematological hematological changes hematology hemoglobin increase in infections information Long Lower management metabolism morphology neurodegenerative disorders oxidative stress patients with COVID-19 Prevent progressed progression promote Red red blood cells reported rigidity risk SARS-CoV-2 severe COVID-19 shown the disease Viral viral infection worsening [DOI] 10.3390/ijms23042171 PMC 바로가기 [Article Type] Review
Decreased serum levels of angiotensin converting enzyme (ACE)2 and enhanced cytokine levels with severity of COVID-19: normalisation upon disease recoveryResearch Article Published on 2022-02-162022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] acute respiratory syndrome Admission affected Angiotensin-converting enzyme baseline Blood cause circulating cytokine clinical outcomes Combination component coronavirus coronavirus disease COVID-19 cytokine level Cytokines Decreased Dexamethasone disease disease severity ELISA enrolled enzyme Future HCs healthy control IL-6 IL-8 increase in Infection main receptor Mild moderate Moderate COVID-19 moderate disease Normalisation objective Patient patient group patients treated patients with moderate PCR-confirmed peripheral pilot study promote Remdesivir renin-angiotensin system Result sACE2 SARS-CoV-2 Serum level severe COVID-19 patient severe disease severity significantly significantly increased subject systemic systemic cytokine treated Treatment was obtained were measured [DOI] 10.1016/j.heliyon.2022.e08957 PMC 바로가기 [Article Type] Research Article
Suicide and drug toxicity mortality in the first year of the COVID-19 pandemic: use of medical examiner data for public health in Nova ScotiaCOVID-19 대유행 첫 해의 자살 및 약물 독성 사망률: 노바스코샤의 공중 보건을 위한 검시관 데이터 사용Article Published on 2022-02-162022-09-11 Journal: Health promotion and chronic disease prevention in [Category] COVID19(2023년), SARS, 치료기술, [키워드] applied cause cause of death change Characteristics collaboration coroners COVID-19 COVID-19 pandemic death diver drug overdose drug toxicity engage English examiner expected Factors French instance Manner of death medical examiner medical examiners mental illness Mortality nous Nova overdose pandemic première processus public health public health surveillance raised reduction reduction in remained response risk risk ratio service Suicide Surveillance TEMPS Toxicity [DOI] 10.24095/hpcdp.42.2.02 PMC 바로가기 [Article Type] Article
E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2Article Published on 2022-02-152022-10-31 Journal: Cell Death Discovery [Category] COVID-19, [키워드] airway Alter Analysis antiviral response cause Cell change decreased expression Defense demonstrated diacetyl disease dysregulation epithelial genomic Health Host host susceptibility hypoxia impaired lung function in vitro increase in Infectious diseases Inflammation Inflammatory interferon-stimulated gene lung lung epithelium morphology Obstructive occupational Pathways Respiratory tract diseases risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA susceptibility transcriptional profiles transcriptomic understanding [DOI] 10.1038/s41420-022-00855-3 PMC 바로가기 [Article Type] Article
MPO-ANCA-positive Microscopic Polyangiitis Following COVID-19 InfectionCOVID-19 감염에 따른 MPO-ANCA 양성 현미경적 다발혈관염Article Published on 2022-02-152022-09-11 Journal: Internal medicine (Tokyo, Japan) [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, [키워드] anti-SARS-CoV-2 Antibody titers Antineutrophil cytoplasmic antibody cause concerning Course COVID-19 COVID-19 infection cytokine Cytokine storm cytoplasmic disease Glomerulonephritis immune response immunosuppressive immunosuppressive therapy Infection lead Microscopic MPO-ANCA organs Patient polyangiitis Precaution rapidly progressive glomerulonephritis reported SARS-CoV-2 SARS-COV-2 infection serum antibody subsequent Symptom systemic disease therapy triggered vaccination Vasculitis [DOI] 10.2169/internalmedicine.8615-21 PMC 바로가기 [Article Type] Article
Understanding the role of telomere attrition and epigenetic signatures in COVID-19 severityCOVID-19 심각도에서 텔로미어 마모 및 후성 유전적 서명의 역할 이해Review Published on 2022-02-152022-09-11 Journal: Gene [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] association Asymptomatic attrition biological processe cause causes concerning coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 severity death DNA methylation elderly patients Epigenetic explain form Genetic hallmark health system heterogeneous higher risk highlight immune response Infectious disease Infectious diseases Inter-individual variation inter-individual variations interstitial pneumonia knowledge mechanism Mild miRNA expression outbreak outcome pandemic Pathogenesis profile Respiratory failure respiratory tract illness SARS-CoV-2 severe COVID-19 severe interstitial pneumonia severity severity of COVID-19 Spread telomere therapeutic intervention understanding upper respiratory tract viral infection [DOI] 10.1016/j.gene.2021.146069 PMC 바로가기 [Article Type] Review
Lockdowns and Physical Activities: Sports in the Time of COVIDReview Published on 2022-02-152022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] activities aging cause caused conditions coronavirus correlated country COVID COVID-19 decrease develop Effect Health health preservation Health status Isolation knowledge Life expectancy literature review maintain pandemic physical physical activities physical activity problem recommendation reduction in social classes sport sports time Topic [DOI] 10.3390/ijerph19042175 PMC 바로가기 [Article Type] Review
Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein혈소판은 SARS-CoV-2 스파이크 단백질에 의한 염증성 단핵구 활성화를 매개합니다Research Article Published on 2022-02-152022-09-10 Journal: The Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] activate Activation affected causative agent cause CD40 CD40L correlated COVID-19 cytokine Cytokine storm disorder disorders Engagement explain Hemostasis Hypercoagulation individual Inflammation inflammatory monocyte manifestation Mild mild to moderate mild to moderate disease moderate disease monocyte Monocyte activation Monocytes morbidity morbidity and mortality Most patients Patient Platelet Platelets Proinflammatory cytokine promoted receptor risk SARS-CoV-2 SARS-CoV-2 spike protein severe COVID-19 signaling pathway Spike protein the SARS-CoV-2 therapeutic intervention [DOI] 10.1172/JCI150101 PMC 바로가기 [Article Type] Research Article
Adipose tissue in COVID-19: detection of SARS-CoV-2 in adipocytes and activation of the interferon-alpha responseCOVID-19의 지방 조직: 지방 세포에서 SARS-CoV-2 감지 및 인터페론-알파 반응 활성화Original Article Published on 2022-02-152022-09-10 Journal: Journal of Endocrinological Investigation [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료법, [키워드] ACE2 gene activate Activation adipocyte adipocytes adipose Adipose tissue Adults age and sex Alpha alteration appear association Autopsy BMI cardiac death cause causes Cell characterization Control controls COVID-19 COVID-19 case COVID-19 cases COVID-19 cohort cytoplasm death Deceased fat Features form Genome IFN IFN-alpha Immune transcriptome immune-related genes infect infiltrating Inflammatory mediators interferon interferon-alpha investigation leukocyte leukocytes lung parenchyma mechanism mediators moderate moderate to severe nucleocapsid antigen obesity objective parenchymal Pathogenesis pathway PCR progression proportion Result risk factor RT-PCR SARS-CoV-2 SARS-CoV-2 genome severe disease severe forms of COVID-19 specimen Subcutaneous subcutaneous fat subject sudden cardiac death the SARS-CoV-2 the SARS-CoV-2 genome tissue Transcription trauma upregulation virus virus antigen virus antigens [DOI] 10.1007/s40618-022-01742-5 PMC 바로가기 [Article Type] Original Article