Influence of SARS-CoV-2 inactivation by different chemical reagents on the humoral response evaluated in a murine model쥐 모델에서 평가된 체액 반응에 대한 다양한 화학 시약에 의한 SARS-CoV-2 비활성화의 영향Article Published on 2022-07-012022-09-12 Journal: Molecular immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition Administered anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antigen antigenic biosafety Brazil cell culture supernatant Cytopathic effect ELISA ELISA assay evaluate evaluated expressive formaldehyde glutaraldehyde highest humoral IgG immunization immunized immunogen inactivated Inactivated virus inactivation influence mice murine model Neutralizing neutralizing antibody observation pandemic plaque polymerase chain PRNT PRNT(50) protocol purified quantification reagent real time risk RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 viral subsequent Test the SARS-CoV-2 Toxicity Treatment verification Vero cells Viral antigen viral inactivation Viral protein virus was performed [DOI] 10.1016/j.molimm.2022.05.012 PMC 바로가기 [Article Type] Article
A typhoid fever protein capsular matrix vaccine candidate formulated with Advax-CpG adjuvant induces a robust and durable anti-typhoid Vi polysaccharide antibody response in mice, rabbits and nonhuman primatesResearch article Published on 2022-07-012022-10-05 Journal: Vaccine [Category] 비임상, [키워드] aluminum Antibody Response asked B cell memory boost capsular catalyzed CD4 dose elicited Fever glutaraldehyde IgG IgG level IgG levels IgG response immune immunization IMPROVE induce lack mice NHP non-human primate overcome Phase 1 phosphate polysaccharide polysaccharide vaccine Protein repeated response robust Salmonella serum single dose stimulated subsequent sustained T cell Trial Vaccine vaccine candidate [DOI] 10.1016/j.vaccine.2022.06.043 [Article Type] Research article
COVID-19 clinical features in primary care: COVIDPAP study1차 진료에서의 COVID-19 임상 특징: COVIDPAP 연구Observational Study Published on 2022-07-012022-09-11 Journal: Anales de pediatria [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, [키워드] age antigen detection Asymptomatic Asymptomatic cases Atención primaria children clinical feature clinical picture Community Community pediatrics compatible symptom compatible symptoms Contact tracing cough COVID-19 COVID-19 pandemic deaths described diagnose disease English Fever followed by headache health center Hospital admission Hospitalized household hubo IgG incidence Infancia Inflammatory Inpatient Inpatients media Mild Mild disease MOST observational study Pandemia Patient PCR pediatric Pediatric case pediatric cases positive primary care resource rhinorrhea SARS-CoV-2 serology significant difference Spain Spanish Symptom Symptoms syndrome to define Transmission Viral RNA was performed women [DOI] 10.1016/j.anpede.2022.06.004 PMC 바로가기 [Article Type] Observational Study
Prevalence of COVID-19-associated symptoms during acute infection in relation to SARS-CoV-2-directed humoral and cellular immune responses in a mild-diseased convalescent cohort경증 회복기 코호트에서 SARS-CoV-2 유도 체액 및 세포 면역 반응과 관련하여 급성 감염 중 COVID-19 관련 증상의 유병률Article Published on 2022-07-012022-09-12 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute infection antibody antiviral immunity association Cellular immune response cellular immune responses Cohort convalescent convalescent individual correlation cough COVID-19 COVID-19 symptom COVID-19 symptoms disease severity effective eight evaluated humoral humoral immune response humoral immune responses IgG immune immune response intensities intensity Loss of Smell majority no difference polymerase chain positive Prevalence Prevent questionnaire recent reduced SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2-specific T cell Serum level severe symptom severity shown Symptom symptom severity Symptoms T cell response T cells virus clearance were assessed [DOI] 10.1016/j.ijid.2022.04.019 PMC 바로가기 [Article Type] Article
Antibody response to the messenger RNA-1273 vaccine (Moderna) in liver transplant recipients간 이식 환자에서 메신저 RNA-1273 백신(모더나)에 대한 항체 반응Article Published on 2022-07-012022-09-12 Journal: Hepatology communications [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Administered anti-S anti-S IgG antibody cause clinical coronavirus coronavirus disease COVID-19 COVID-19 infection develop dose evaluated examined Factor first vaccination Follow-up General population Hepatitis IgG Immunoglobulin Immunological response immunosuppressive include interquartile range laboratory data liver Liver transplantation Logistic regression LTR LTRs median median age men Messenger RNA Moderna MOST Most patient mRNA mRNA-1273 vaccine mRNA-based vaccine Odds ratio Patient positive predict receiving recipient recipients regimen response RNA-1273 SARS-CoV-2 Serologic response shown tested the spike protein the vaccine university Vaccine vaccine dose [DOI] 10.1002/hep4.1937 PMC 바로가기 [Article Type] Article
Successful Treatment of SARS-CoV-2 Vaccination-related Activation of Rheumatoid Arthritis with Positive Findings for Epstein-Barr VirusEpstein-Barr 바이러스에 대한 양성 결과로 류마티스 관절염의 SARS-CoV-2 백신 접종 관련 활성화의 성공적인 치료Case Reports Published on 2022-07-012022-09-12 Journal: Internal medicine (Tokyo, Japan) [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome administration Antigen clinical disease coronavirus COVID-19 Disease activity EBV Epstein-Barr virus Fever finding IgG introduced joint polyarthritis Protein Rheumatoid rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 vaccination Tocilizumab treat Vaccine virus [DOI] 10.2169/internalmedicine.9433-22 PMC 바로가기 [Article Type] Case Reports
SARS-CoV-2 Incidence, signs and symptoms and main risk factors for COVID-19 infection in Health Care Workers: A hospital-wide survey in Salvador, BrazilArticle Published on 2022-07-012022-11-15 Journal: The Brazilian journal of infectious diseases : an [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome affected age Ageusia antibody association Brazil Characteristics conducted coronavirus country COVID-19 COVID-19 infection cross-sectional ELISA evaluated Factor for inclusion HCW HCWs Health care healthcare worker higher risk hospital identify IgG IgG and IgM incidence Infection information knowledge likelihood logistic regression model mitigate occupational occupational health participant positive positive IgG antibody positive RT-PCR proportion Questionnaires Ratio reported risk factor RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 antibodies selected significantly higher Social inequalities Symptom Symptoms tested the disease Topic variable with COVID-19 women Workplace [DOI] 10.1016/j.bjid.2022.102387 PMC 바로가기
Analysis of IgG, IgA and IgM antibodies against SARS-CoV-2 spike protein S1 in convalescent and vaccinated patients with the Pfizer-BioNTech and CanSinoBio vaccinesPfizer-BioNTech 및 CanSinoBio 백신을 사용한 회복기 및 백신 접종 환자의 SARS-CoV-2 스파이크 단백질 S1에 대한 IgG, IgA 및 IgM 항체 분석Article Published on 2022-07-012022-09-11 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] antibodies antibody Antibody detection Antibody Response CanSinoBio Complete convalescent COVID-19 detect diagnostic disease dose ELISA ELISA test evaluate IgA IgG IgG antibodies IgG antibody IgM IgM antibody individual induce mRNA natural infection no difference no differences number of persons onset of symptoms pandemic pandemic spread pandemic virus Patient Pfizer Pfizer-BioNTech Prevalence question recognize S1 S1 protein SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 virus significantly higher Spread Symptoms the antibody response the S1 protein therapy vaccinated individuals vaccination Vaccine Vaccines variant virus Wuhan Wuhan, China [DOI] 10.1111/tbed.14344 PMC 바로가기 [Article Type] Article
Immunogenicity of the third and fourth BNT162b2 mRNA COVID-19 boosters and factors associated with immune response in patients with SLE and rheumatoid arthritis세 번째 및 네 번째 BNT162b2 mRNA COVID-19 부스터 및 SLE 및 류마티스 관절염 환자의 면역 반응과 관련된 인자의 면역원성Article Published on 2022-07-012022-09-11 Journal: Lupus science & medicine [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] adenoviral vector Administered anti-RBD Anti-RBD IgG Arthritis benefit BNT162b2 BNT162b2 mRNA booster booster dose booster vaccination cellular Cellular immune response COVID-19 domain enrolled evaluate Factor heterogenous humoral Humoral response IgG immune response immunogenicity immunosuppressive inactivated Inactivated vaccine initial Lupus lupus erythematosus Lupus Erythematosus, Systemic mRNA vaccines Neutralising activity occurred omicron Omicron variant Patient positive raised RBD RBD IgG registration number rheumatoid arthritis significantly SLE systemic titre vaccination Vaccine variant was done were given [DOI] 10.1136/lupus-2022-000726 PMC 바로가기 [Article Type] Article
Reduced neutralizing antibody potency of COVID-19 convalescent vaccinated plasma against SARS-CoV-2 Omicron variantSARS-CoV-2 오미크론 변이체에 대한 COVID-19 회복기 백신 접종 혈장의 중화 항체 효능 감소Article Published on 2022-07-012022-09-11 Journal: Vox Sanguinis [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] anti-IgG Anti-S1 antibody assays B.1 best binding coefficient collected convalescent convalescent plasma correlated correlation coefficient COVID-19 D614G Donor fraction highest IgG IgG level Immunocompromised patient Immunocompromised patients Infection median Mutation NAb Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Omicron variant plasma Quantitative reduced relationship resulting SARS-CoV-2 selected significantly lower Spearman Strains threshold titre titres vaccination variant [DOI] 10.1111/vox.13279 PMC 바로가기 [Article Type] Article