Nano-multilamellar lipid vesicles promote the induction of SARS-CoV-2 immune responses by a protein-based vaccine formulationArticle Published on 2022-09-012022-11-15 Journal: Nanomedicine : nanotechnology, biology, and medici [Category] SARS, 진단, [키워드] Activation acute respiratory syndrome addition antibody Antigen C57BL/6 CD4 Complete conditions coronavirus COVID-19 demonstrated Diseases displaying dose effective hallmark highlight IgG immune response immunization in vitro in vivo Lipid-based nanoparticles mice modulated MPLA Nano-multilamellar vesicles promote Protein RBD Receptor binding domain reduced required responses Safe SARS-CoV-2 serum spike subunit Subunit vaccine T-cell Response T-cell responses toxic effect Vaccine Vaccines Vesicle virus-neutralizing antibody [DOI] 10.1016/j.nano.2022.102595 PMC 바로가기
The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workersCOVID-19 위험 평가(RECOVER) 연구의 재감염: 캐나다 의료 종사자 집단의 재감염 및 혈청학 역학Observational Study Published on 2022-09-012022-09-11 Journal: Influenza and Other Respiratory Viruses [Category] COVID19(2023년), SARS, 변종, 임상, 치료기술, [키워드] absence age average Characteristics Cohort conducted COVID-19 Efficacy estimation Follow-up HCWs healthcare healthcare worker IgG immune response incidence rate management median natural immunity natural infection obesity Other pandemic PCR-confirmed Primary infection prospective cohort study prospective studies Reinfection remained SARS-CoV-2 SARS-COV-2 infection serological serology Seropositivity Spike protein the spike protein Uncertainty understanding vaccination variants [DOI] 10.1111/irv.12997 PMC 바로가기 [Article Type] Observational Study
Immunosuppressed non-responders to two doses of mRNA SARS-CoV-2 vaccines achieve an immune response comparable to those of immunocompetent individuals after a third doseArticle Published on 2022-09-012022-11-15 Journal: Hormones (Athens, Greece) [Category] COVID19(2023년), SARS, 진단, [키워드] anti-CD20 antibody response against Antibody titer appear Autoimmune disorders cancers cascade cell-mediated immune comparable disease dose elevated Glucocorticoids Hematological malignancies immune response Immunocompromised Immunosuppressed Immunosuppression individual induce inhibitor methotrexate MMF monoclonal antibody MOST mRNA mRNA SARS-CoV-2 vaccines. neutralizing antibody non-responder Patient proportion Protein Rapamycin recipient S protein SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines Signaling solid cancers solid organ transplant suggested the SARS-CoV-2 the SARS-CoV-2 virus third dose transplantation Treatment Vaccine Vaccines variety while [DOI] 10.1007/s42000-022-00365-y PMC 바로가기
Humoral and adaptive immune responses to the SARS-CoV-2 vaccineArticle Published on 2022-09-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation Adaptive immune response Adaptive immunity adverse outcome B.1.1.7 B.1.617.2 Blood booster booster dose CD8+ Delta dose hallmark healthy volunteer high affinity humoral humoral immune response Humoral response IFN-γ immune response Infection memory mRNA vaccine neutralizing antibody nine omicron phenotype protective antibody response SARS-CoV-2 SARS-CoV-2 specific antibody SARS-CoV-2 spike antigen SARS-CoV-2 vaccines second vaccination sera Serum level subset T cell the SARS-CoV-2 vaccination Vaccine Wuhan [DOI] 10.1016/j.ijid.2022.06.020 PMC 바로가기
Potential mechanism of SARS-CoV-2-associated central and peripheral nervous system impairmentReview Published on 2022-09-012023-07-09 Journal: Acta neurologica Scandinavica [Category] COVID19(2023년), [키워드] Central nervous system COVID-19 immune response Neuropathy SARS-CoV-2 [DOI] 10.1111/ane.13657 PMC 바로가기 [Article Type] Review
Humoral immune response to authentic circulating severe acute respiratory syndrome coronavirus 2 variants elicited by booster vaccination with distinct receptor-binding domain subunits in mice생쥐에서 뚜렷한 수용체 결합 도메인 소단위로 부스터 백신 접종에 의해 유도된 진정한 순환 중증 급성 호흡기 증후군 코로나바이러스 2 변이체에 대한 체액 면역 반응Article Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Antibody titer Antibody titers binding booster booster vaccination circulating comparable coronavirus coronavirus disease Coronavirus disease 2019 domain dose Efficacy elicited expected humoral immune response Immune escape immune response immunization immunogens induce mice Mutation Neutralizing antibody titer neutralizing antibody titers omicron Protein RBD RBD protein respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly increased Spike protein subunit the spike protein Vaccine vaccine efficacy variant variants virus strain virus strains wild type [DOI] 10.1002/jmv.27882 PMC 바로가기 [Article Type] Article
Acute kidney injury associated to COVID-19 leads to a strong unbalance of circulant immune mediatorsCOVID-19와 관련된 급성 신장 손상은 순환 면역 매개체의 강한 불균형으로 이어집니다Article Published on 2022-09-012022-09-12 Journal: Cytokine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] accompanied Acute kidney injury AKI AKI patient AKI patients alteration analyzed association CCL-2 CCL-3 clinical outcomes contribute coronavirus disease COVID-19 COVID-19 patient CXCL-10 CXCL-8 Cytokines death demonstrated diabete Follow-up Frequency hospital discharge hospitalized patient IFN-γ IL-10 IL-2 IL-6 immune Immune mediators. immune response immunoassay immunopathological increased risk investigated kidney Kidney injury male moderate multiplex Patient performed Predictive ROC Curve SARS-CoV-2 viral load severe COVID-19 significantly significantly higher sustained the disease timepoint TNF-α VEGF Viral load were measured [DOI] 10.1016/j.cyto.2022.155974 PMC 바로가기 [Article Type] Article
Association of mental health with clinical outcomes in hospitalized patients with moderate COVID-19Research article Published on 2022-09-012022-10-05 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 바이오마커, [키워드] addition adjusted adjusted hazard ratio Admission age Anxiety association Clinical outcome clinical outcomes clinically conducted coronavirus disease COVID-19 COVID-19 pandemic Cox regression analysis Critical death Depression Diagnosis discharge duration of hospitalization Epidemiology HADS highlight Hospital stay hospitalized patient immune response incidence Laboratory male management marker mental health mental health problem moderate Moderate COVID-19 objective participant Patient Primary outcome prospective cohort study Result risk scale secondary outcome significantly were assessed Wuhan, China [DOI] 10.1016/j.jad.2022.05.047 [Article Type] Research article
Assessment of humoral immune response to two mRNA SARS-CoV-2 vaccines (Moderna and Pfizer) in healthcare workers fully vaccinated with and without a history of previous infectionArticle Published on 2022-09-012022-11-15 Journal: Journal of Applied Microbiology [Category] COVID19(2023년), SARS, 진단, [키워드] Abbott analysed Analysis anti-S IgG anti-S IgG SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody assessment BNT162b2 contribute decrease eight healthcare healthcare worker Healthcare workers humoral immune response IgG IgG response immune immune response Immune status in both group Infection knowledge mean value Moderna mRNA mRNA SARS-CoV-2 vaccines mRNA-1273 Patient persist Pfizer positive post-vaccination. Presence revaccination RIPOVAC SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine Significance significantly higher Spain System vaccination Vaccination strategy Vaccine was performed [DOI] 10.1111/jam.15699 PMC 바로가기
A Review on Immunological Responses to SARS-CoV-2 and Various COVID-19 Vaccine RegimensArticle Published on 2022-09-012022-11-16 Journal: Pharmaceutical research [Category] 변종, [키워드] B cell responses BBIBP-CorV caused clinical trial convalescent convalescent individual convalescent individuals CoronaVac COVID-19 COVID-19 patients COVID-19 vaccine effective effective vaccine Efficacy Efficiency Health immune immune response Immunity Immunological response imperative implementation inactivated investigated long-lasting mechanism NVX-CoV2373 phase Prophylactic regimen regimens Reinfection reported response review RNA SARS-CoV-2 the vaccine transmission of SARS-CoV-2 Vaccine vaccine regimens. Vaccines variant virus [DOI] 10.1007/s11095-022-03323-w PMC 바로가기