Comparison of anti-SARS-CoV-2 IgG and IgA antibody responses post complete vaccination, 7 months later and after 3rd dose of the BNT162b2 vaccine in healthy adults건강한 성인의 BNT162b2 백신 3차 접종 후 7개월 후와 완전 백신 접종 후 항 SARS-CoV-2 IgG와 IgA 항체 반응 비교Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Administered administration Adults anti-SARS-CoV-2 IgG antibody antibody levels Antibody Response approved BNT162b2 BNT162b2 vaccine booster booster dose Complete COVID-19 COVID-19 vaccine decrease domain dose ELISA assay European Medicines Agency geometric geometric mean healthy higher risk IgA IgA antibodies IgA antibody IgG individual individuals mRNA new SARS-CoV-2 of BNT162b2 Older Sample SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants second dose semi-quantitative serum sample serum samples Significant significant decrease significantly tested the SARS-CoV-2 vaccinated individual vaccinated individuals vaccination Vaccine variant variants virus were assessed [DOI] 10.1016/j.jcv.2022.105193 PMC 바로가기 [Article Type] Article
Evaluation of humoral and cellular response to third dose of BNT162b2 mRNA COVID-19 vaccine in patients treated with B-cell depleting therapyB세포 고갈 요법으로 치료받은 환자에서 BNT162b2 mRNA COVID-19 백신 3차 접종에 대한 체액 및 세포 반응 평가Article Published on 2022-07-012022-09-11 Journal: Journal of autoimmunity [Category] MERS, 바이오마커, 유전자 메커니즘, 진단, [키워드] affected anti-CD20 anti-S anti-SARS-CoV-2 antibody Autoimmune disease B-cell BNT162b2 CD-20 CD20 cellular immunity cellular response Cohort COVID-19 COVID-19 vaccination COVID-19 vaccine depleting dose doses drug group healthy control healthy controls humoral humoral and cellular immunity IFN-g IgG IMID Immune-mediated inflammatory disease Immune-mediated inflammatory diseases immunogenic immunogenicity Immunosuppressed immunosuppressed patient immunosuppressed patients Inflammatory diseases interferon mRNA mRNA COVID-19 vaccine mRNA COVID-19 vaccines naïve Neutralization assay neutralization assays neutralization titer neutralization titers Neutralizing antibodies neutralizing antibody no significant difference of BNT162b2 Patient patients treated Quantitative reduced response seroconverted significant difference significantly spike subject therapy These data treated vaccination [DOI] 10.1016/j.jaut.2022.102848 PMC 바로가기 [Article Type] Article
Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine나노입자 전달 TLR4 및 RIG-I 작용제는 SARS-CoV-2 소단위 백신에 대한 면역 반응을 향상시킵니다Article Published on 2022-07-012022-09-11 Journal: Journal of controlled release : official journal o [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] activated Adaptive immune response adjuvant adjuvants agonist Anti-spike anti-Spike IgG Antibody titer Antibody titers Antigen antigen-presenting cell antigen-presenting cells APC APCS B cell B cells BAL Bcl6 Blood bronchoalveolar CD4 CD44 Cell cell population characterized Combination adjuvant COVID-19 COVID-19 protein subunit vaccine CpG DLNs draining lymph node draining lymph nodes Efficacy ENhance follicular Germinal center GL7 helper cell humoral immune responses IgA IgG immune immune response immune responses Immunity IMPROVE in vitro in vivo Increases increases in Infection intramuscular intramuscular vaccination intranasal Intranasal versus intramuscular vaccination intranasally lead lung Lungs lymphocyte memory T memory T cell mice molecular Monophosphoryl lipid A MPLA Native neutralizing antibody titers Pattern recognition pattern recognition receptor Pattern recognition receptors Polymer Population Proinflammatory cytokine Protein subunit protein subunit vaccine Protein subunit vaccines PRR PRRs PUUC reaction receptor receptors responses against retinoic acid retinoic acid-inducible gene I RIG-I robust S1 subunit SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein secretion spike IgA Spike protein stabilized spike protein stimulate subunit Subunit vaccine T cell T cell proliferation the S1 subunit TLR TLR4 TLR7 TLR7/8 TLR9 TLRs Toll-like receptor Toll-like receptors Transmission unique Vaccine vaccine availability vaccine responses variants [DOI] 10.1016/j.jconrel.2022.05.023 PMC 바로가기 [Article Type] Article
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum폴리(I:C) 플러스 명반과 관련된 SARS-CoV-2 삼량체 스파이크 단백질의 면역원성Article Published on 2022-06-302022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition adjuvant adjuvants alum antibody B cell BALF Bronchoalveolar lavage fluid CD4 CD8 Cellular immune response Combination domain ELISA enzyme evaluated expected germinal centers IgA IgG IgG anti-spike antibody IgG1 IgG2a immunization immunogenicity immunosorbent in vitro inactivated induce intradermal route lung Lung inflammation mice Neutralization assay Neutralizing titer neutralizing titers neutrophil recruitment New Poly (I:C) poly(I:C positive prefusion produced producing Protein RBD reduced reduction in required SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 virus serum spike Spike protein Subtypes supported T cell Th1 Th1 phenotype the SARS-CoV-2 trimeric vaccination Vaccination strategy Vaccine [DOI] 10.3389/fimmu.2022.884760 PMC 바로가기 [Article Type] Article
Evaluation of IgM and IgG in COVID-19 Recovered Patients in IraqArticle Published on 2022-06-302023-07-11 Journal: Archives of Razi Institute [Category] COVID19(2023년), [키워드] COVID-19 IgG IgM recovered patients severity [DOI] 10.22092/ARI.2022.357515.2054 PMC 바로가기
Seroconversion Rate After SARS-CoV-2 Infection and Two Doses of Either ChAdOx1-nCOV COVISHIELD™ or BBV-152 COVAXIN™ Vaccination in Renal Allograft Recipients: An Experience of Two Public and Private Tertiary Care CenterSARS-CoV-2 감염 후 혈청전환율 및 ChAdOx1-nCOV COVISHIELD™ 또는 BBV-152 COVAXIN™ 백신 2회 접종 후 신장 동종이식 환자: 2개의 공립 및 사립 3차 치료 센터 경험Article Published on 2022-06-302022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] anti- SARS-CoV-2 antibody anti-SARS-CoV-2 antibody formation Antibody titer appear center chemiluminescence COVAXIN™ COVISHIELDTM dose effective elevated evaluated experience high mortality humoral Humoral immunity IgG immunoassay Immunocompromised induce Infection median Microparticle Mortality natural infection Neutralizing antibody titer on type Private Public Rate recipient reported response robust SARS-CoV-2 SARS-COV-2 infection Seroconversion seroconversion rate serum Spike protein Tertiary the SARS-CoV-2 Transplant vaccination Vaccine Vaccines was measured [DOI] 10.3389/fimmu.2022.911738 PMC 바로가기 [Article Type] Article
A Molecular Analysis of Memory B Cell and Antibody Responses Against Plasmodium falciparum Merozoite Surface Protein 1 in Children and Adults From Ugandaarticle Published on 2022-06-302024-09-01 Journal: Frontiers in immunology [Category] 말라리아, [키워드] Adaptive immune response antibodies Humoral immunity IgG IgM malaria memory B cells Somatic hypermutation [Article Type] article
Role of Fc Core Fucosylation in the Effector Function of IgG1 AntibodiesIgG1 항체의 이펙터 기능에서 Fc 코어 푸코실화의 역할Review Published on 2022-06-302022-09-12 Journal: Frontiers in Immunology [Category] MERS, 진단, [키워드] ADCC ADCP antibody Antigen approved B-cell Cancer Cell cellular cytotoxicity Clinical use core decrease Dengue disease severity Effect effector Efficacy ENhance fetal fucosylation function highlighting human IgG1 Fc humoral Humoral response IgG IgG Fc IgG1 IgG1 antibody immune in vitro in vivo Infection Inflammatory diseases knowledge less mAb mAbs Macrophage mechanism Modification monoclonal antibody N-glycan natural immune response natural killer NK cells parasites phagocytosis Platelet polyclonal polymorphonuclear neutrophil pregnant women Regulation reported role SARS-CoV 2 Seven shown significantly therapeutic therapeutic antibodies treat virus virus infection [DOI] 10.3389/fimmu.2022.929895 PMC 바로가기 [Article Type] Review
Increased Serum IgG Antibody, Avidity, and Surrogate Virus Neutralization Response after a Third Dose for the BNT162b2 mRNA Vaccine to SARS-CoV-2Article Published on 2022-06-302022-11-15 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), SARS, 진단, [키워드] avidity BNT162b2 mRNA IgG Increased response SARS-CoV-2 surrogate [DOI] 10.1093/jalm/jfac018 PMC 바로가기
SARS-CoV-2 Circulation during the First Year of the Pandemic: A Seroprevalence Study from January to December 2020 in Tuscany, Italy팬데믹 첫 해 동안의 SARS-CoV-2 순환: 이탈리아 투스카니에서 2020년 1월부터 12월까지의 혈청 유병률 연구Article Published on 2022-06-302022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] affected anti-receptor-binding domain antibody collected country COVID-19 cases diffusion ELISA epidemiological General population IgG IgM IgM and IgG in-house ELISA increase in Italy neutralizing antibody positive Prevalence RBD RBD IgG SARS-CoV-2 Seroprevalence serum sample Siena subsequent Surveillance tested the SARS-CoV-2 Tuscany virus spread Year [DOI] 10.3390/v14071441 PMC 바로가기 [Article Type] Article