pulmonary disease – Page 44 – Communicable Diseases Research

Causal relationships between obesity and the leading causes of death in women and men

비만과 여성과 남성의 주요 사망 원인 사이의 인과 관계

Research Article

Published on 2019-10-242022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] adjusted Affect Analysis association blood pressure BMI body mass body mass index cardiometabolic disease cardiometabolic diseases causal relationship causal relationships cause Chronic kidney disease chronic liver disease chronic obstructive chronic obstructive pulmonary disease chronic renal failure Cochran’s Q-test Coronary artery Coronary artery disease death diabete diabetes Diabetes Mellitus disease disease risk downstream Effect etiological Fatty liver fatty liver disease genetic data genetic risk score genetic variants glycemic GRS heart disease higher risk implicated implication increase increased risk indicate instrumental variable instrumental variables investigated involved Kidney disease lung cancer majority mediators men men and women mendelian randomization Mortality Non-alcoholic fatty liver disease non-communicable diseases obesity obstructive pulmonary disease preventative measure public health pulmonary disease renal renal failure risk smoking Still stroke traits type 2 diabete type 2 diabetes UK biobank waist waist-hip ratio Waist-hip-ratio WHR women
[DOI] 10.1371/journal.pgen.1008405 PMC 바로가기 [Article Type] Research Article

Generation of a Nebulizable CDR-Modified MERS-CoV Neutralizing Human Antibody

Article

Published on 2019-10-122022-10-29
Journal: International Journal of Molecular Sciences [Category] Coronavirus,

[키워드] accumulated administration aerosol delivery aggregates amino acids antibody antibody engineering CDRs clone complementarity-determining region complementarity-determining regions FIVE generate Generation glycoprotein greater HCDR HCDR3 Human hydrophobic residue induce infected patients introduced LCDRs lung tissue mechanical ventilation MERS-CoV Middle East Modification Mutation nebulizer Neutralizing Neutralizing activity neutralizing antibody physiological Protein pulmonary disease pulmonary diseases RBD reactive reactivity replaced residue Respiratory failure respiratory syndrome coronavirus resulting S RBD significantly stability the receptor-binding domain therapeutic Val
[DOI] 10.3390/ijms20205073 PMC 바로가기 [Article Type] Article

A Human DPP4-Knockin Mouse’s Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV

Article

Published on 2018-08-232022-10-28
Journal: Viruses [Category] Coronavirus,

A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques

Article

Published on 2018-07-162022-10-29
Journal: Scientific Reports [Category] Coronavirus, MERS,

Histopathology case definition of naturally acquired Salmonella enterica serovar Dublin infection in young Holstein cattle in the northeastern United States

article

Published on 2017-11-302024-09-01
Journal: Journal of Veterinary Diagnostic Investigation [Category] 살모넬라증,

[키워드] Bacterial infection cattle Histopathology pulmonary disease Salmonella Sepsis
[Article Type] article

Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in mice

Article

Published on 2016-11-012023-06-24
Journal: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology [Category] 신종인플루엔자,

[키워드] metabolic pathway analysis mouse lung metabolome pulmonary disease targeted metabolic intervention.
[DOI] 10.1152/ajpregu.00298.2016 PMC 바로가기

Streptococcus pneumoniae colonisation in children and adolescents with asthma: impact of the heptavalent pneumococcal conjugate vaccine and evaluation of potential effect of thirteen-valent pneumococcal conjugate vaccine

천식이 있는 아동 및 청소년에서의 폐렴구균 감염: 7가 폐렴구균 결합 백신의 영향과 13가 폐렴구균 결합 백신의 잠재적 효과 평가

Research Article

Published on 2016-01-122024-08-04
Journal: BMC Infectious Diseases [Category] 폐렴구균 감염증,

[키워드] Asthma Asthmatic children chronic respiratory disease PCV13 PCV7 Pneumococcal colonisation pneumococcal conjugate vaccine pulmonary disease Streptococcus pneumoniae
[DOI] 10.1186/s12879-016-1335-3 PMC 바로가기 [Article Type] Research Article

Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels

Alpha1-항트립신 혈청 수준이 있는 SERPINA 유전자 클러스터의 변이체의 인과적 및 합성적 연관성

Research Article

Published on 2013-08-222022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] accelerated allele Alpha1-antitrypsin Analysis antitrypsin association Author Blood Causal chromosomal locus chronic obstructive chronic obstructive pulmonary disease circulating city Cohort common variants complex Concentration contribute COPD deficiency defined Degradation determined driven by Effect emphysema enzyme examined example explained functional gene cluster General population Genetic genetic determinant genetic determinants Genetic polymorphism genetic polymorphisms Genetic variant Genome-wide association study genome-wide significance genotyped genotyping GWAS Health heart hidden independent individual inhibitor Level locus Lung function MAF MAFs Meta-analysis minor allele frequency nucleotide obstructive pulmonary disease participant phenotype PI polymorphism PROTECT Protein pulmonary disease pulmonary tissue reached reduce replicated Replication respiratory risk risk factor SERPINA1 SERPINA1 gene Serum level serum levels Single nucleotide polymorphism single nucleotide polymorphisms Smokers SNP SNPs subsequent suggested Support synthetic tissue transfer Variability variant variants while
[DOI] 10.1371/journal.pgen.1003585 PMC 바로가기 [Article Type] Research Article