[Potential therapies for COVID-19 cardiovascular complications using artemisinin and its derivatives intervene based on its cardiovascular protection]Article Published on 2020-12-012023-07-12 Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of [Category] SARS, [키워드] 2019-nCoV Artemisinin artemisinin derivatives cardiovascular disease COVID-19 Drug repurposing Heart injury [DOI] 10.19540/j.cnki.cjcmm.20200828.601
Artificial intelligence in COVID-19 drug repurposingCOVID-19 약물 용도 변경의 인공 지능Review Published on 2020-12-012022-09-11 Journal: International Journal of Environmental Research an [Category] SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] accelerate AI approach AI approaches approach artificial intelligence COVID-19 COVID-19 pandemic disease Diseases drug Drug repurposing example human disease information medication offer Precision provide reduced repositioning review target targets technique therapeutic Therapeutics timeline treat [DOI] 10.1016/S2589-7500(20)30192-8 PMC 바로가기 [Article Type] Review
Interferon-inducer antivirals: Potential candidates to combat COVID-19Review Published on 2020-12-012022-10-04 Journal: International immunopharmacology [Category] MERS, SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome adverse effect Antibiotics Antiviral antiviral agent Antiviral effect antivirals approach benefit candidate category Compound compounds coronavirus Coronavirus disease 2019 COVID-19 database Defense disease drug drug candidate Drug repurposing effective evaluated examined help immune response immune system immunosuppressants induce infective interferon lack management mechanism non-steroidal anti-inflammatory drug pandemic Potential risk SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Side effects signaling pathway Structure synergistic the interferon treating COVID-19 Treatment treatment for COVID-19 triggering Type type I interferon urgency [DOI] 10.1016/j.intimp.2020.107245 PMC 바로가기 [Article Type] Review
Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2Article Published on 2020-12-012023-07-13 Journal: International journal of biological macromolecules [Category] SARS, [키워드] 3CL-protease Activity inhibition Drug repurposing [DOI] 10.1016/j.ijbiomac.2020.08.166 PMC 바로가기
Artemisinins as a novel anti-cancer therapy: Targeting a global cancer pandemic through drug repurposingReview article Published on 2020-12-012022-10-05 Journal: Pharmacology & therapeutics [Category] 신약개발, [키워드] Anti-cancer therapy antimalarial drug Artemisinin artemisinins artesunate Cancer class clinical trial daily dose death disease Drug repurposing greater income indicated majority middle occur oncology pandemic Pathways significantly targeting therapeutic Tolerability Treatment unique variety [DOI] 10.1016/j.pharmthera.2020.107706 [Article Type] Review article
One year update on the COVID-19 pandemic: Where are we now?Review Published on 2020-11-282023-05-31 Journal: Acta tropica [Category] MERS, SARS, 조류인플루엔자, [키워드] coronavirus COVID-19 Drug repurposing outbreak pandemic Pathogenesis SARS-CoV-2 Therapeutics Vaccines [DOI] 10.1016/j.actatropica.2020.105778 PMC 바로가기 [Article Type] Review
Decoding information on COVID–19: Ontological approach towards design possible therapeuticsReview article Published on 2020-11-272022-10-05 Journal: Informatics in Medicine Unlocked [Category] 신약개발, 치료제, [키워드] “cytokine storm” accelerate Antiviral approach caused Characteristics Comorbidities country COVID-19 curative Decoding drug Drug repurposing effective effective vaccine Factor globe Host host-pathogen interaction identification immune response information Intervention less medical intervention Mortality mortality rate mutant virus ontological Ontology pathogen Prevalence researcher respiratory SARS CoV-2 significantly spread to target protein targets the disease therapy unique Vaccine variations virus [DOI] 10.1016/j.imu.2020.100486 [Article Type] Review article
Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In VitroArticle Published on 2020-11-262022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome Analysis Antiviral antiviral activity Box Calu-3 candidate drug Care cell line Combined Compound compound screen confirmed case coronavirus deaths Drug repurposing FIVE Health human lung identification in vitro inhibited inhibiting initial multiple cell line occur pandemic pandemic response box Prophylactic Remdesivir response Retro-2.1 SARS-CoV-2 SARS-CoV-2 replication screened selected therapeutic intervention These data Vero E6 Vero E6 cell viral replication [DOI] 10.3390/microorganisms8121872 PMC 바로가기 [Article Type] Article
A ligand-based computational drug repurposing pipeline using KNIME and Programmatic Data Access: case studies for rare diseases and COVID-19Educational Published on 2020-11-252022-10-31 Journal: Journal of Cheminformatics [Category] COVID-19, [키워드] accelerate Analysis antiviral drug application application programming interface approach ChEMBL Chemical Computational drug COVID 19 COVID-19 data access data curation Data integration Data mining deficiency Developed disease Drug discovery Drug repurposing DrugBank GLUT-1 deficiency syndrome Guide-to-pharmacology in silico include increasingly information interface KNIME workflow Open targets platform PDB platform provide provided PubChem rare disease researcher resource SARS-CoV-2 Scientific community service Substructure search syndrome transporter Type UniProtKB [DOI] 10.1186/s13321-020-00474-z PMC 바로가기 [Article Type] Educational
Comparative transcriptome analysis of SARS-CoV, MERS-CoV, and SARS-CoV-2 to identify potential pathways for drug repurposingComparative Study Published on 2020-11-242023-06-14 Journal: Computers in biology and medicine [Category] MERS, SARS, [키워드] coronavirus COVID-19, coronavirus disease-2019 drug candidates Drug repurposing MERS-CoV, Middle East respiratory syndrome Meta-analysis SARS-CoV-2 SARS-COV-2, severe acute respiratory syndrome coronavirus-2 SARS-CoV, severe acute respiratory syndrome Transcriptome [DOI] 10.1016/j.compbiomed.2020.104123 PMC 바로가기 [Article Type] Comparative Study