New Metrics for Evaluating Viral Respiratory PathogenesisResearch Article Published on 2015-06-262022-10-28 Journal: PLoS ONE [Category] Coronavirus, 신종인플루엔자, [키워드] change changes in clinically connection evaluate Evaluating highlight human disease Infection marker Measures methodology Metrics mice New Pathogenesis Pulmonary function respiratory Respiratory function respiratory viral infections respiratory virus responses SARS-CoV severe systemic disease utility viral pathogenesis virus was used [DOI] 10.1371/journal.pone.0131451 PMC 바로가기 [Article Type] Research Article
The clinical impact of coronavirus infection in patients with hematologic malignancies and hematopoietic stem cell transplant recipientsArticle Published on 2015-04-152023-06-15 Journal: Journal of Clinical Virology [Category] MERS, [키워드] coronavirus Hematologic malignancy Hematopoietic stem cell transplant respiratory virus [DOI] 10.1016/j.jcv.2015.04.012 PMC 바로가기 [Article Type] Article
Overview of the 3rd isirv-Antiviral Group Conference – advances in clinical managementMeeting Report Published on 2015-01-152022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] Coronavirus, [키워드] Antiviral antivirals approved Clinical management Conference current group highlight Immunocompromised Immunocompromised patient Influenza Influenza virus MERS-CoV pandemic respiratory respiratory infection respiratory syncytial virus respiratory virus rhinovirus RSV Treatment Vaccine [DOI] 10.1111/irv.12293 PMC 바로가기 [Article Type] Meeting Report
Detection of respiratory viruses in gargle specimens of healthy childrenArticle Published on 2015-01-132022-11-01 Journal: Journal of Clinical Virology [Category] Coronavirus, [키워드] acute respiratory illness addition Adenovirus ADV, adenovirus asked Asymptomatic asymptomatic infection children children’s health circulation Clinical outcome clinical symptom Coinfection collected conditions coronavirus coronavirus 229E detect detection disease EV, enterovirus Factor Fever FluV, influenza virus gargle Gargle specimen HBoV, human bocavirus hCoV OC43 HCoV, human coronavirus Health status healthy children HKU1 hMPV, human metapneumovirus Host hPeV, human parechovirus immune system Infection objective OC43 other respiratory virus parainfluenza parent PCR PCR positivity PCR, polymerase chain reaction PIV, parainfluenza virus polymerase chain reaction Prevalence Real-time PCR respiratory respiratory syncytial virus respiratory virus respiratory viruses Result rhinovirus RSV RSV, respiratory syncytial virus RT, reverse transcription RV, rhinovirus RVA, rhinovirus genogroup A RVB, rhinovirus genogroup B RVC, rhinovirus genogroup C sensitivity specimen Symptom symptomatic Symptoms tested viral infection virus viruses without symptoms [DOI] 10.1016/j.jcv.2015.01.006 PMC 바로가기 [Article Type] Article
Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown virusesOriginal Articles Published on 2015-01-042022-10-30 Journal: Influenza and Other Respiratory Viruses [Category] Coronavirus, [키워드] air–liquid interface Airway epithelial cultures airway epithelium analyzed Antibody detection can be used Cell cell tropism clinical sample convalescent serum Culture detect Ex vivo experiment Genome HAE human airway epithelial Human airway epithelium human coronavirus OC43 identify indicated infected cell influenzavirus B molecular Next-generation sequencing primary cell progeny provide Replication respiratory virus respiratory viruses Result sequence Sequencing tested the patient tracheobronchial VIDISCA-454 viral genome sequence virus virus discovery was used were infected were stained [DOI] 10.1111/irv.12297 PMC 바로가기 [Article Type] Original Articles
Development of SPR biosensor for simultaneous detection of multiplex respiratory virusesArticle Published on 2015-01-012023-06-25 Journal: Bio-medical materials and engineering [Category] 신종인플루엔자, [키워드] gene chip high throughput Label-free respiratory virus SPR [DOI] 10.3233/BME-151526
Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolatesResearch Article Published on 2014-12-222022-10-28 Journal: BMC Genomics [Category] Coronavirus, [키워드] Activation acute respiratory syndrome Amino acid Analysis analyzed approach Atypical Calu-3 caused Cell cell line changes changes in clinical Clustering Computational topology coronavirus Cytokine simulation differential expression epithelial Extracellular feature filtered Gene Expression highly pathogenic homology host response human airway epithelial human Calu-3 humans IFN IL-1α in viral include Infection innate immune Innate immunity isolate kinetic magnitude MERS MERS-CoV MERS-CoV infection Middle East modulate Novel coronavirus pathogenic patients performed persistence Pneumonia post infection pro-inflammatory pro-inflammatory responses progressive respiratory failure Protein respiratory virus responses Result SARS-CoV Signaling STAT3 statistical analysis strain Strains supplementary material syndrome TNF transcriptional transcriptional change transcriptional difference transcriptomics zoonotic [DOI] 10.1186/1471-2164-15-1161 PMC 바로가기 [Article Type] Research Article
Respiratory viruses, such as 2009 H1N1 influenza virus, could trigger temporal trends in serotypes causing pneumococcal disease호흡기 바이러스, 예를 들어 2009 H1N1 인플루엔자 바이러스는 폐렴구균 질환을 유발하는 혈청형의 일시적인 경향을 유발할 수 있다.journal-article Published on 2014-12-012024-08-04 Journal: Clinical Microbiology and Infection [Category] 폐렴구균 감염증, [키워드] Influenza pneumococcal disease respiratory virus serotypes Streptococcus pneumoniae [DOI] 10.1111/1469-0691.12744 [Article Type] journal-article
Is There Still Room for Novel Viral Pathogens in Pediatric Respiratory Tract Infections?Research Article Published on 2014-11-202022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Adding addition ambulatory patient approach Bacteria children clinically deep sequencing Diagnosis Diagnostic method DNA DNA library Hospitalized hospitalized patients in both groups Infection less metagenomic Nasopharyngeal swab novel novel virus outpatients pathogen pathogenic pathogenic bacteria patient group PCR pediatric Pneumonia Population positive respiratory Respiratory disease respiratory infection respiratory sample respiratory syncytial virus respiratory virus rhinovirus room sequenced Sequencing Still tract upper respiratory tract virus viruses [DOI] 10.1371/journal.pone.0113570 PMC 바로가기 [Article Type] Research Article
Human coronaviruses: Viral and cellular factors involved in neuroinvasiveness and neuropathogenesisReview Published on 2014-10-022022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] Affect Asthma Autoimmunity Cell cellular Central nervous system CNS CNS infection colds coronavirus demonstrated described disease distress Encephalitis etiology Factor Health hematogenous Host Host immune response Human human coronavirus humans individuals induce Infants infect infecting Infection Invasion involved Lower respiratory tract mice neurodegeneration neuroinvasion Neuroinvasive neurologic Neurological diseases Neurological disorders Neuron pathogen pathogenic processe Pathogens Pneumonia populations problems Regulation reported respiratory pathogen respiratory tract respiratory viral infection respiratory virus respond Spread suggested susceptible individual syndrome target cell triggering upper respiratory tract viral invasion viral replication virus Virus life cycle viruses [DOI] 10.1016/j.virusres.2014.09.011 PMC 바로가기 [Article Type] Review