Evaluation of sixteen ELISA SARS-CoV-2 serological tests16개의 ELISA SARS-CoV-2 혈청 검사 평가Article Published on 2021-09-012022-09-12 Journal: Journal of Clinical Virology [Category] SARS, 진단, [키워드] antibody Complete COVID-19 COVID-19 pandemic cross-reactivity defined ELISA evaluated Evaluation excluded exclusion criteria expression heterogeneity IgA IgG IgM independent investigated Patient positive positive RT-PCR post-symptom onset reactive respiratory viruses SARS-CoV-2 sensitivity sera serological serological test specificity specimen viral infections were excluded [DOI] 10.1016/j.jcv.2021.104931 PMC 바로가기 [Article Type] Article
TOP-Plus Is a Versatile Biosensor Platform for Monitoring SARS-CoV-2 Antibody DurabilityTOP-Plus는 SARS-CoV-2 항체 내구성 모니터링을 위한 다목적 바이오센서 플랫폼입니다Article Published on 2021-09-012022-09-12 Journal: Clinical Chemistry [Category] SARS, 진단, [키워드] acute respiratory syndrome antibody Antibody avidity Antibody titer biosensor comparable coronavirus coronavirus disease correlated COVID-19 COVID-19 vaccination described evaluated examined IgG IgM IgM antibody level Immunity include individual infected individual infected with SARS-CoV-2 Infection initial Interaction Interferometry monitoring neutralization activity neutralizing antibody Patient platform raised SARS-CoV-2 sera serological Serological assay significantly test-on-a-probe biosensors the antibody response undetectable vaccinated individual vaccination Vaccine [DOI] 10.1093/clinchem/hvab069 PMC 바로가기 [Article Type] Article
Nine Cases of SARS-CoV-2-PCR-positive Samples Showed No Increase of Antibodies Against SARS-CoV-2SARS-CoV-2-PCR 양성 샘플 9건에서 SARS-CoV-2에 대한 항체 증가 없음Article Published on 2021-09-012022-09-12 Journal: In vivo (Athens, Greece) [Category] SARS, 진단, [키워드] absence activating adaptive affecting Against analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibodies Care collected coronavirus 2 COVID-19 hospital IgG immune reaction increase innate immune Innate immunity Japan Nurse outbreak PCR-positive provide respiratory RT-qPCR Sample SARS-CoV-2 sera serum sample Showed virus [DOI] 10.21873/invivo.12587 PMC 바로가기 [Article Type] Article
Comparable endemic coronavirus nucleoprotein-specific antibodies in mild and severe Covid-19 patients경증 및 중증 Covid-19 환자에서 유사한 풍토성 코로나바이러스 핵단백질 특이적 항체Article Published on 2021-09-012022-09-12 Journal: Journal of medical virology [Category] SARS, 진단, [키워드] antibodies antibody Asymptomatic comparable contribute coronavirus COVID-19 Critical cross-reactive immune response death disease disease severity Endemic Endemic coronaviruses healthy Immunity Infection Mild nucleoprotein-specific antibodies. Patient Potential Respiratory disease SARS-CoV-2 SARS-COV-2 infection sera severe symptoms severity Severity of disease subjects Variability [DOI] 10.1002/jmv.27038 PMC 바로가기 [Article Type] Article
Preliminary evidence of blunted humoral response to SARS-CoV-2 mRNA vaccine in multiple sclerosis patients treated with ocrelizumab오크렐리주맙으로 치료받은 다발성 경화증 환자에서 SARS-CoV-2 mRNA 백신에 대한 체액 반응 둔화의 예비 증거Article Published on 2021-09-012022-09-11 Journal: Neurological Sciences [Category] MERS, SARS, 진단, 치료기술, [키워드] all subject all subjects Anti-spike anti-Spike IgG Antibody Units baseline BAU binding antibody units BNT162b2 Case series case sery collected COVID-19 COVID-19 infection develop DiaSorin disease expand first dose geometric geometric mean health-care healthy subject healthy subjects humoral Humoral response IgG antibodies IgG antibody immunogenicity Infection International international standard majority mounted mRNA mRNA vaccine Multiple multiple sclerosis Ocrelizumab patients treated preliminary evidence relapsing SARS-CoV-2 SARS-CoV-2 mRNA vaccine SARS-CoV-2 spike protein SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARSCoV-2 second dose second dose of vaccine sera serum sample serum samples Spike protein tested Therapies treated unit Vaccine were expressed [DOI] 10.1007/s10072-021-05397-7 PMC 바로가기 [Article Type] Article
Cytokine Profiles Associated With Worse Prognosis in a Hospitalized Peruvian COVID-19 Cohort입원한 페루 COVID-19 코호트에서 더 나쁜 예후와 관련된 사이토카인 프로필Immunology Published on 2021-09-012022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 진단, [키워드] 95% confidence interval 95%CI activated adaptive analyses Analysis analyzed anti-Spike IgG anti-spike IgG antibodies Anti-spike IgG antibody antibody concentration baseline Biomarker Biomarkers C-reactive protein chemokine chemokines clinical parameter Clinical parameters Cohort Concentration correlated COVID-19 COVID-19 patient creatinine criteria CRP cytokine Cytokines D-dimer D-dimer levels death determine died discharge disease severity e parameters ELISA enrolled evaluated exacerbated expression expression profile fatal COVID-19 form Frequency GM-CSF groups growth factor Growth factors hazard ratio hemoglobin hospital Hospitalization Hospitalized hospitalized COVID-19 patients identify IL-10 IL-12p70 IL-15 IL-5 IL-6 IL-8 IL1RA Immune cell immune cells Inflammation laboratory-confirmed Laboratory-confirmed COVID-19 Logistic regression longitudinal longitudinal analysis longitudinal samples lymphocyte Lymphocytes MCP-1 MIP-1α moderate disease Mortality multivariable analysis Neutrophils obesity outcome outcomes parameter Patient patient information patients with moderate Peripheral blood pro-inflammatory cytokines profile Prognosis proinflammatory Protein Quantitative Result risk factor SARS-CoV-2 IgG SARS-CoV-2 infected patient SARS-CoV-2 infected patients SARS-COV-2 infection sera severe disease severity Significant significant difference significant differences spike IgG Stratification TNFα worse prognosis [DOI] 10.3389/fimmu.2021.700921 PMC 바로가기 [Article Type] Immunology
BNT162b2 SARS-CoV-2 Vaccination Elicits High Titers of Neutralizing Antibodies to Both B.1 and P.1 Variants in Previously Infected and Uninfected SubjectsBrief Report Published on 2021-08-292022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] B.1 B.1 variant baseline BNT162b2 Cohort correlated cross-neutralization Diagnosis driven by HCW Health care worker health care workers healthy highlighting infected individual Lineage live virus neutralization median Neutralizing antibodies Neutralizing antibody titer P.1 P.1 variant P.1 variants previously infected and uninfected subjects receiving SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 variant sera significantly significantly higher strain subject subjects tested titer uninfected vaccination vaccine dose variant [DOI] 10.3390/life11090896 PMC 바로가기 [Article Type] Brief Report
Antibody-Mediated Neutralization of Authentic SARS-CoV-2 B.1.617 Variants Harboring L452R and T478K/E484QL452R 및 T478K/E484Q를 보유한 정통 SARS-COV-2 B.1.617 변이체의 항체-매개 중화Communication Published on 2021-08-262022-09-01 Journal: Viruses [Category] MERS, SARS, 변종, 진단, [키워드] B.1 B.1.617 B.1.617.1 B.1.617.2 BNT2b2 Casirivimab Cell Cell culture circulating combination therapy convalescent convalescent sera Corona virus Delta effective Efficiency Epsilon Factor greater Imdevimab infections Kappa L452R less mAb mAbs monoclonal antibodies monoclonal antibody mRNA1273 neutralization Neutralization assay neutralize no difference performed reduced reduction SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera susceptibility susceptible T478K vaccination variant [DOI] 10.3390/v13091693 PMC 바로가기 [Article Type] Communication
Performance comparison of micro-neutralization assays based on surrogate SARS-CoV-2 and WT SARS-CoV-2 in assessing virus-neutralizing capacity of anti-SARS-CoV-2 antibodiesShort Communications Published on 2021-08-262022-10-28 Journal: Access Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibody characterized coronavirus COVID-19 enzyme immunoassay Laboratory microneutralization neutralization Neutralization assay neutralizing capacity offer performance PRNT SARS CoV-2 SARS-CoV-2 sera serology virus virus-neutralizing wild-type WT SARS-CoV-2 [DOI] 10.1099/acmi.0.000257 PMC 바로가기 [Article Type] Short Communications
Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals회복기 개인의 SARS-CoV-2 감염에 대한 성 격차 및 중화항체 내구성Research Article Published on 2021-08-252022-09-12 Journal: mSphere [Category] MERS, SARS, 진단, [키워드] age antibodies antibody Antibody titer association binding antibody cardiometabolic caused clinical parameter Clinical parameters Cohort collected Comorbidities Comorbidity convalescent coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19-convalescent individual COVID-19-convalescent individuals death discrepancy disparity Donor evaluated expand female functional functional antibody response functional antibody responses human antibody response immunology individual Infection longitudinal samples magnitude male Male sex morbidity and mortality Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses Neutralizing antibody titer pandemic positive RBD reason reason for Receptor binding domain responses robust SARS-CoV-2 SARS-CoV-2 antigen sera serum antibodies Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus Sex significantly Support Symptom symptom onset [DOI] 10.1128/mSphere.00275-21 PMC 바로가기 [Article Type] Research Article