Influenza vaccination during the coronavirus pandemic: intention to vaccinate among the at-risk population in the Central Catalonia Health Region (VAGCOVID)Research Published on 2021-05-012022-10-28 Journal: BMC Family Practice [Category] COVID-19, SARS, [키워드] age Attitudes coronavirus Coverage COVID-19 determine Express Factor groups had no health knowledge Human influenza IMPROVE individual Influenza influenza infection influenza vaccination influenza vaccines Influenza virus Intention not express pandemic participant Perceived risk Practice predictor promote public health Region Result risk risk factor SARS-CoV-2 pandemic seasonal Seasonal influenza severe complication SIV supplementary material the SARS-CoV-2 Transmission vaccinate vaccination vaccination coverage Vaccination refusal Vaccine [DOI] 10.1186/s12875-021-01434-8 PMC 바로가기 [Article Type] Research
SARS-CoV-2 infection of Chinese hamsters (Cricetulus griseus) reproduces COVID-19 pneumonia in a well-established small animal model중국 햄스터(Cricetulus griseus)의 SARS-CoV-2 감염은 잘 정립된 작은 동물 모델에서 COVID-19 폐렴을 재현합니다Article Published on 2021-05-012022-09-12 Journal: Transboundary and emerging diseases [Category] SARS, 진단, [키워드] accompanied animal model applied Body weight loss bronchitis caused Chinese hamster Clinical symptoms coronavirus COVID-19 Cricetulus demonstrated experimental animal models feature Genome griseus Histopathology Infection Lower respiratory tract medical intervention molecular pandemic Pathogenesis Pneumonia pre-clinical testing Research robust SARS-COV-2 infection SARS-CoV-2 pandemic susceptible the disease Therapies therapy Transcriptome vaccination Vaccine virus replication [DOI] 10.1111/tbed.13837 PMC 바로가기 [Article Type] Article
[How does one die from SARS-CoV-2 infection? Analysis of the death process in patients admitted to an acute hospital]Observational Study Published on 2021-05-012022-10-05 Journal: Journal of healthcare quality research [Category] SARS, 임상, [키워드] Admission analysed Care Characteristics collected Coma coronavirus Costa del Sol cross-sectional Cuidados paliativos death died effort End End of life English Final de la vida Gripe Health Health Service Influenza intensive care limitation material mortality rate OMS palliative Palliative care Pandemia pandemic Patient patients positive Quality SARS-CoV-2 SARS-CoV-2 pandemic Sedation Sin Spanish susceptible therapeutic variable were recorded WHO World Health Organization [DOI] 10.1016/j.jhqr.2020.11.006 PMC 바로가기 [Article Type] Observational Study
Exploring insights of hydroxychloroquine, a controversial drug in Covid-19: An updateCovid-19에서 논란의 여지가 있는 약물인 하이드록시클로로퀸에 대한 통찰력 탐색: 업데이트Review Published on 2021-05-012022-09-11 Journal: Food and chemical toxicology : an international jo [Category] 신약개발, 치료제, [키워드] analysed article Asymptomatic Chloroquine clinical clinical trial conducted COVID-19 COVID-19 patients Efficacy extreme HCQ health worker higher risk Hydroxychloroquine include management mechanism Mild mild symptoms Neutral pandemic parameter Patient Pharmacodynamics pharmacokinetic pharmacokinetics Prophylactic regimen reported Research SARS-CoV-2 SARS-CoV-2 pandemic stages Symptoms the SARS-CoV-2 Toxicity Treatment Trial utility [DOI] 10.1016/j.fct.2021.112106 PMC 바로가기 [Article Type] Review
Understanding Laboratory Testing for SARS-CoV-2Opinion Published on 2021-04-292022-10-31 Journal: Children [Category] COVID-19, [키워드] Antibody testing approved Clinical diagnosis COVID Critical Drug administration Emergency use authorization environmental factor Epidemiology EUA FDA Host impacted IMPROVE limitations nucleic acid amplification test pandemic point-of-care test rapid antigen test RT-PCR SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 test serological test serology Testing therapeutic decision understanding [DOI] 10.3390/children8050355 PMC 바로가기 [Article Type] Opinion
The Unfolded Protein Response and Autophagy on the Crossroads of Coronaviruses Infections코로나바이러스 감염의 교차로에서 펼쳐진 단백질 반응과 자가포식Review Published on 2021-04-282022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, [키워드] addition autophagy autophagy machinery balance calcium cell death cellular cellular components cellular response Chloroquine component components conserved coronavirus Coronavirus infection CoV debatable debate Degradation drug Each Efficacy Endoplasmic reticulum environmental condition environmental conditions eukaryotic cell eukaryotic cells function functions generate highlighting homeostasis host-pathogen interaction in some include increasingly Infection infections instance integrated stress response involved matter mechanism modulate molecular interaction molecular mechanism molecular mechanisms niclosamide outcome pathway Pathways Perturbation perturbations promote Protein redox status replicative respond response SARS-CoV-2 pandemic signaling pathway spermine Stress suggested Support survival therapeutic options Topic Transcription translation unfolded protein response UPR Vesicle Viral viral infections viral replication virus viruses [DOI] 10.3389/fcimb.2021.668034 PMC 바로가기 [Article Type] Review
In Vitro Lung Models and Their Application to Study SARS-CoV-2 Pathogenesis and DiseaseReview Published on 2021-04-282022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] air–liquid interface application Cell culture cell culture system Coronaviruses COVID-19 develop disease Efficiency Ex vivo ex vivo lung globe help human airway epithelial cell culture human lung organoids in vitro in vitro lung model lung-on-a-chip mechanisms Model Replication SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 pathogenesis Spread Treatment vaccination [DOI] 10.3390/v13050792 PMC 바로가기 [Article Type] Review
Cigarette Smoke Exposure, Pediatric Lung Disease, and COVID-19Physiology Published on 2021-04-272022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] acute lung injury acute respiratory distress acute respiratory syndrome addition Adults Affect ARDS Asthma caused children children’s health chronic respiratory diseases cigarette cigarette smoke exposure complications contrary coronavirus Coronavirus disease 2019 COVID-19 COVID-19 case CSE death detrimental effect develop disease disorders E-cigarette Effect elevated exposure highlight Hospitalization incline Infant infected with SARS-CoV-2 Infection Inflammation Inflammatory likelihood lung Manifestations mechanical ventilation Mild outcome oxygen pediatric Population Premature Prevalence public health respiratory symptom risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic severe COVID-19 significantly smoke smoking spectrum of disease Spread susceptibility symptomatic infection syndrome vaping virus wheezing [DOI] 10.3389/fphys.2021.652198 PMC 바로가기 [Article Type] Physiology
Impact of SARS-CoV-2 Pandemic and Strategies for Resumption of Activities During the Second Wave of the Pandemic: A Report From Eight Paediatric Hospitals From the ECHO NetworkPublic Health Published on 2021-04-262022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] activities activity adopted Care children clinical activity component COVID-19 cross-sectional Diagnosis eight European evaluate Health hospital hospitals Impact impacted infected patients Infection inpatient admission Intensive management network pandemic Perspective preparedness provide report respiratory response restart routine SARS CoV-2 SARS-CoV-2 SARS-CoV-2 pandemic second Significant reduction Strategy Telemedicine tertiary care hospital the SARS-CoV-2 Wave were used [DOI] 10.3389/fpubh.2021.630168 PMC 바로가기 [Article Type] Public Health
From Multiplex Serology to Serolomics—A Novel Approach to the Antibody Response against the SARS-CoV-2 Proteome다중 혈청학에서 혈청학으로 - SARS-CoV-2 단백질체에 대한 항체 반응에 대한 새로운 접근Article Published on 2021-04-242022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] age Algorithm Analysis Antibody Response Antibody responses assays ccCoVs Cohort common cold common cold Coronaviruses Control Course COVID-19 case COVID-19 patient determine Disease progression dual E. coli ELISA enzyme-linked immunosorbent expressed fluorescent HEK293 cells hospitalized patient Ig isotype Ig isotypes immunofluorescence Immunoglobulin multiplex serology novel pathogen Pathogens Protein proteome Receptor-binding domain Research question response SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 epidemiology SARS-CoV-2 N SARS-CoV-2 pandemic SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 proteome SARS-CoV-2 research sensitivity Sensitivity and specificity Serological assay serological assays specificity Spike protein symptom onset the receptor-binding domain the SARS-CoV-2 the spike protein [DOI] 10.3390/v13050749 PMC 바로가기 [Article Type] Article