Modifications to the delivery of NHS face-to-face general practice consultations during the COVID-19 pandemic in EnglandBrief Report Published on 2021-11-012022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] Care clinical clinically conditions coronavirus COVID-19 COVID-19 pandemic delivery model diagnosed element England English face-to-face consultation face-to-face contact flexible General practice group Health identify Impact Local management Modification NHS offered pandemic Patient patients primary care Registered remote responsible SARS-CoV-2 separated Transmission transmission of SARS-CoV-2 virus were used [DOI] 10.12688/f1000research.52161.3 PMC 바로가기 [Article Type] Brief Report
Tocilizumab administration for the treatment of hospitalized patients with COVID-19: A systematic review and meta-analysis코로나19 입원환자 치료를 위한 토실리주맙 투여: 체계적 고찰 및 메타분석Review Published on 2021-11-012022-09-12 Journal: Respirology (Carlton, Vic.) [Category] MERS, SARS, 진단, [키워드] 95% CI administration Admission benefit clinically composite endpoint coronavirus coronavirus disease Corticosteroids COVID-19 Cytokine storm Effectiveness Efficacy evaluate Hospitalization hospitalized COVID-19 patients hospitalized patient ICU improved mortality IMV intensive care Invasive mechanical ventilation lower mortality management Meta-analysis Mortality nine non-ICU patient non-ICU patients observational studies observational study outcome Patient patients Randomized controlled trial RCT RCTs receiving reduction reduction in risk SARS-CoV-2 searched Secondary objective subgroup systematic review systemic corticosteroids Tocilizumab Treatment was reduced [DOI] 10.1111/resp.14152 PMC 바로가기 [Article Type] Review
Depressive Symptoms Among Older Adults Pre- and Post-COVID-19 PandemicObservational Study Published on 2021-11-012022-10-05 Journal: Journal of the American Medical Directors Associat [Category] SARS, 임상, [키워드] 95% CI Ageing Care center clinically conducted confidence interval COVID-19 COVID-19 pandemic Depression depressive symptom Effect Final Follow-up Health care system implication Improving incidence increase in large cohort longitudinal mental health mental health problem observational study Older pandemic Prevalence Prevent public health measure scale setting shielding significant increases in Symptom Symptoms were measured were used [DOI] 10.1016/j.jamda.2021.09.003 PMC 바로가기 [Article Type] Observational Study
City-level SARS-CoV-2 sewage surveillance도시 수준 SARS-CoV-2 하수 감시Article Published on 2021-11-012022-09-11 Journal: Chemosphere [Category] SARS, 치료기술, [키워드] Ashkelon can be used circulation city clinically COVID-19 COVID-19 pandemic Disease activity early warning economics epidemiological epidemiological surveillance Epidemiology expressed fecal green Healthcare systems in viral increase in indicated Infection load methodology morbidity Normalized viral load NVL outbreak Population population level Population monitoring recent resurgence SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Society Surveillance tested to define Viral load Viral RNA virus wastewater wastewater epidemiology [DOI] 10.1016/j.chemosphere.2021.131194 PMC 바로가기 [Article Type] Article
Treatment of ChAdOx1 nCoV-19 Vaccine-Induced Immune Thrombotic Thrombocytopenia Related Acute Ischemic StrokeChAdOx1 nCoV-19 백신 유발 면역 혈전성 혈소판 감소증 관련 급성 허혈성 뇌졸중의 치료Case Reports Published on 2021-11-012022-09-12 Journal: Journal of stroke and cerebrovascular diseases : t [Category] MERS, 진단, [키워드] 24 hour acute respiratory syndrome adenoviral vector vaccine antibody anticoagulation Brain ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinically complications coronavirus effective eligible feasible female first dose Hemorrhagic heparin-induced thrombocytopenia hypercoagulable immune initiated intravenous Intravenous immunoglobulin Ischemic Laboratory large vessel life-threatening Mechanical Mechanical thrombectomy mechanism occurred onset of symptoms Patient PF4 Platelet Presence presenting reported Restenosis SARS-CoV-2 stroke Surveillance thrombocytopenia thrombosis thrombotic Treatment vaccination VITT [DOI] 10.1016/j.jstrokecerebrovasdis.2021.106072 PMC 바로가기 [Article Type] Case Reports
Phase I study in healthy participants to evaluate safety, tolerability, and pharmacokinetics of inhaled nezulcitinib, a potential treatment for COVID-19Clinical Trial Published on 2021-11-012022-10-05 Journal: Clinical and translational science [Category] 임상, [키워드] acute lung injury administration All participant cell count clinically Cohort coronavirus disease COVID-19 dose double-blind evaluate evaluated expected healthy Inhaled inhibitor Jak lack matching placebo Mild moderate multiple ascending dose multiple dose natural killer nezulcitinib Part participant Participants pharmacological phase Phase I placebo-controlled plasma plasma concentration Potential treatment Primary outcome Randomized receive reductions in secondary outcome severity single ascending dose TD-0903 TEAE TEAEs Tolerability Treatment treatment-emergent adverse event [DOI] 10.1111/cts.13123 PMC 바로가기 [Article Type] Clinical Trial
Machine Learning-based Voice Assessment for the Detection of Positive and Recovered COVID-19 PatientsResearch article Published on 2021-11-012022-10-05 Journal: Journal of Voice [Category] 바이오마커, 진단, 치료기술, [키워드] Accuracy All study participant assessment Asymptomatic AUC binary classification carried clinically Comparisons conducted controls cough COVID COVID-19 COVID-19 patients COVID-19 symptom detectable detection determine diagnostic effective healthy individual healthy individuals healthy subjects identify individual Infection machine nasal swab outlined pandemic Patient patients Population positive positive COVID-19 provided recovered recovered COVID-19 patient recruited reported SARS-CoV-2 screening strategy screening test sensitivity Serological testing specificity Spread subject subjects subpopulation Surveillance sustained the disease Trial Variation virological test voice [DOI] 10.1016/j.jvoice.2021.11.004 [Article Type] Research article
Covid-19 and oral diseases: Crosstalk, synergy or association?코로나19와 구강질환: 누화, 시너지, 연관성?Review Published on 2021-11-012022-09-11 Journal: Reviews in Medical Virology [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Affect alterations angiotensin angiotensin-converting enzyme 2 association Bacterial Blister can not caused clinically cohort study coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Crosstalk Cytokines destruction disease Diseases dysfunction elevated Endothelial cell endothelial cells Endotheliitis erythematous Evidence exacerbating exhibit Express facilitate Gingiva gingivitis growth Gustatory Health human body hyperinflammation Immune-mediated impair Infection Infectious disease Inflammation Interaction lesion lesions Loss of Smell loss of smell and taste manifestation mechanism Multiple multiple organ multiple organs necrotic negative and positive oral cavity oral diseases. oral health oral infection oral manifestation oral tissue Pathogenesis Pathogens pathway Patient plaque plaques proinflammatory mediator proinflammatory mediators promote inflammation recent receptor reported salivary salivary gland SARS-CoV-2 severe acute respiratory syndrome Coronavirus Signs and symptoms subject subjects Symptom synergy Taste tissue homeostasis tissue inflammation viral entry viral infection viral replication virus virus spread [DOI] 10.1002/rmv.2226 PMC 바로가기 [Article Type] Review
Effect of Online 1-Day Cognitive Behavioral Therapy-Based Workshops Plus Usual Care vs Usual Care Alone for Postpartum Depression: A Randomized Clinical TrialRandomized Controlled Trial Published on 2021-11-012022-10-05 Journal: JAMA Psychiatry [Category] Fulltext, MERS, 임상, [키워드] 95% CI added addition Affect age Anxiety assigned baseline Behavior bonding Canada clinical clinically cognitive control group COVID-19 pandemic determine Edinburgh Effect effective eligible exhibiting form GAD-7 Generalized higher odd IMPROVE improvement Infant Odds ratio offspring Older outcome participant positive Postpartum Postpartum depression preference Primary outcome provide randomized clinical trial Randomly receive recruited reduced reducing reductions in Registered reported risk scale secondary significant decrease Support therapy Treatment treatment as usual Virtual care women workshop [DOI] 10.1001/jamapsychiatry.2021.2488 PMC 바로가기 [Article Type] Randomized Controlled Trial
Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 ReplicationArticle Published on 2021-10-302022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] β-apocarotenoic acid Anti-SARS-CoV-2 Activity antibacterial activity antibiotic Antiviral antiviral activity Antiviral effect approved bixin cathepsin B cathepsin L Cell clinically colorant Compound computational studies conjugate COVID-19 pandemic Crocetin drug Efficacy inhibitory action inhibitory activity involved modifications natural protease quantitative PCR ristocetin SARS-CoV-2 synthetic Teicoplanin VERO E6 cells viability viral replication Viral RNA was tested [DOI] 10.3390/ph14111111 PMC 바로가기 [Article Type] Article