Protective heterologous T cell immunity in COVID-19 induced by the trivalent MMR and Tdap vaccine antigens
3가 MMR 및 Tdap 백신 항원에 의해 유도된 COVID-19의 보호 이종 T 세포 면역
Clinical and Translational Article
[키워드] Abstract
Activation
acute respiratory syndrome
Administered
Analysis
Anti-viral immunity
Antibody titers
Antigen
antigen presenting cells
antigens
APC
assays
autologous
CD45RA
Cell
co-cultured
Cohort
Context
Control
coronavirus
coronavirus disease
correlation
COVID-19
COVID-19 patient
COVID-19 patients
COVID-19 vaccination
cross-reactive
death
disease severity
Donor
driving
Effect
effective
effector memory
elicit
ELISA
ELISPOT
ENhance
enzyme-linked immunospot
epitope
feature
Features
finding
flow cytometry
foundation
funding
Heterologous
heterologous immunity
IFN-γ
IL-15
Immunity
implicated
individual
individuals
Infection
interferon-γ
investigated
memory
memory T cells
microbe
mitigate
MMR
nucleocapsid
outcomes
overlapping
Participants
Pathogens
phenotype
promote
PROTECT
Protective
Protein
Reactivation
recognizing
reduced
required
response
risk prediction
SARS-CoV-2
SARS-CoV-2 antigen
scRNA-seq
severe COVID-19
Single-cell RNA sequencing
subset
supported
T cell
TCR
TCR repertoire
transcriptional
Transcriptome
trivalent
uninfected
vaccination
Vaccine
vaccine antigen
Vaccines
validation study
viral infection
with mild disease
[DOI] 10.1016/j.medj.2021.08.004 PMC 바로가기 [Article Type] Clinical and Translational Article
[DOI] 10.1016/j.medj.2021.08.004 PMC 바로가기 [Article Type] Clinical and Translational Article