48 hour – Page 5 – Communicable Diseases Research

Learning From Past Respiratory Infections to Predict COVID-19 Outcomes: Retrospective Study

Original Paper

Published on 2021-02-222022-10-30
Journal: Journal of Medical Internet Research [Category] COVID-19, MERS,

Observational study of haloperidol in hospitalized patients with COVID-19

코로나19로 입원한 환자를 대상으로 한 할로페리돌의 관찰 연구

Clinical Trial

Published on 2021-02-192022-08-13
Journal: PLoS ONE [Category] MERS, 임상, 치료제,

[키워드] 48 hour 48 hours 95% CI Admission Adult patients analyses Analysis antipsychotic Antiviral effect AP-HP assistance association baseline Characteristics Composite COVID-19 death defined discharge home discharged home dose endpoints examined finding Follow-up haloperidol Hospital admission hospitalized patient hospitals In-vitro Inpatient intubation multicenter observational study multiple sensitivity analyses multivariable Cox regression observational study occurred outcome over Paris Patient patients hospitalized patients with COVID-19 PCR test per day positive COVID-19 primary end-point primary endpoint Probability psychotropic medications receiving receptor receptor antagonist Result risk SARS-CoV-2 secondary endpoint Sensitivity analyses suggested survivor univariate Cox regression university Weighting with COVID-19
[DOI] 10.1371/journal.pone.0247122 PMC 바로가기 [Article Type] Clinical Trial

Covid-19 deaths in Africa: prospective systematic postmortem surveillance study

아프리카의 코비드-19 사망: 전향적 체계적인 사후 감시 연구

Article

Published on 2021-02-172022-09-11
Journal: The BMJ [Category] Fulltext, MERS, 치료기술,

[키워드] 48 hour 48 hours acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 African age AIDS alcohol Care Chain Reaction children Community Comorbidity coronavirus coronavirus disease Coronavirus disease 2019 cough Cycle threshold value death diabete diabetes died enrolled Fever FIVE HIV/AIDS hospital hypertension interquartile range location male median age MOST Nasopharyngeal swab nasopharyngeal swabs occurred outcome participant PCR polymerase chain polymerase chain reaction Positive test Postmortem presenting proportion Prospective Quantitative respiratory reverse transcriptase Risk factors SARS-CoV-2 Seven severe acute respiratory syndrome Coronavirus Sex Shortness of breath status stratified Surveillance Symptoms Teaching tested These data transcriptase Tuberculosis typical symptom typical symptoms university
[DOI] 10.1136/bmj.n334 PMC 바로가기 [Article Type] Article

An observational cohort study of bacterial co-infection and implications for empirical antibiotic therapy in patients presenting with COVID-19 to hospitals in North West London

Observational Study

Published on 2021-02-112022-10-05
Journal: Journal of Antimicrobial Chemotherapy [Category] 임상,

[키워드] 48 hour Admission age all-cause mortality Antibiotic therapy Antibiotic treatment Bacterial bacterial co-infection clinically Co-infection co-morbidities collected COVID-19 infection COVID-19 patient CRP Gender hospital Hospital admission hospitalized COVID-19 patient ICU ICU admission illnesses implication in-hospital mortality Infection Inflammatory marker inflammatory markers London majority neutrophil count no significant difference North Observational cohort study Patient patient age presenting Prevalence Result retrospective selected significantly higher specimen Treatment West white cell with COVID-19
[DOI] 10.1093/jac/dkaa475 PMC 바로가기 [Article Type] Observational Study

A Machine Learning Prediction Model of Respiratory Failure Within 48 Hours of Patient Admission for COVID-19: Model Development and Validation

Observational Study

Published on 2021-02-102022-10-04
Journal: Journal of Medical Internet Research [Category] MERS, 임상,

[키워드] 48 hour Accuracy Admission Admitted Patient age artificial intelligence Care characteristic clinical decision collected COVID-19 demographic characteristics Deterioration development died discharged disease Early warning score Emergency failure help highest hospital hour index Invasive mechanical ventilation laboratory data Logistic regression machine learning machine learning approach Metrics Model modeling morbidity and mortality objective oxygen pandemic Patient patients patients with COVID-19 predict prediction Predictive Predictive model predictor variable prognostic reduce resources respiratory Respiratory failure respiratory rate Result risk score serum lactate severe acute respiratory syndrome coronavirus 2 Support the patient validation variable with COVID-19
[DOI] 10.2196/24246 PMC 바로가기 [Article Type] Observational Study

Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: An observational prospective study

COVID-19 중환자에서 예후 마커로서 중부 프로아드레노메둘린(MR-proADM)의 효과: 관찰 전향 연구

Observational Study

Published on 2021-02-082022-08-13
Journal: PLoS ONE [Category] Biochemistry, MERS, 바이오마커, 임상,

[키워드] 48 hour 48 hours 95% confidence interval adjusted Admission age AUC best Biomarkers C-reactive protein cardiovascular disease characterized COVID-19 COVID-19 adult patient COVID-19 ICU-patients COVID-19 patients COVID-19-ICU-patients Critically ill CRP CRP level CRP levels cut-off D-dimer diabetes Diabetes Mellitus dying patient dying patients effective Effectiveness enrolled explain Gender group higher mortality characterized patients ICU ICU admission increase in Laboratory Laboratory test Lactate lactate dehydrogenase LDH log-rank test logistic regression model lymphocyte Lymphocytes lymphocytopenia mechanism mid-regional pro-adrenomedullin Mortality MR-proADM MR-proADM measurement non-survivor NT-pro-BNP objective Odds ratio overall mortality Patient patients PCT predict Predictive procalcitonin Prognostic marker Prospective Study receiver-operating characteristics curves Referral responsible Result significantly Support survival curve Survival curves surviving and non-surviving patients tested university hospital were measured
[DOI] 10.1371/journal.pone.0246771 PMC 바로가기 [Article Type] Observational Study

Microvascular flow alterations in critically ill COVID-19 patients: A prospective study

Research Article

Published on 2021-02-082022-10-28
Journal: PLoS ONE [Category] Coronavirus, MERS,

Management of Renin-Angiotensin-Aldosterone System blockade in patients admitted to hospital with confirmed coronavirus disease (COVID-19) infection (The McGill RAAS-COVID- 19): A structured summary of a study protocol for a randomized controlled trial

코로나바이러스 감염증(COVID-19) 감염이 확인된 병원에 입원한 환자의 레닌-안지오텐신-알도스테론 시스템 차단 관리(The McGill RAAS-COVID-19): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Study Protocol

Published on 2021-02-052022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] 1:1 48 hour 48 hours ACE inhibitor ACE2 Acute kidney injury Admission age aldosterone All participants Amendment Analysis Anticoagulants approach assigned baseline Biomarker Biomarkers blinded Blinding blockade blood pressure BNP C-reactive protein C-reactive protein (CRP calculated calibrated cardiovascular disease change Clinical improvement clinical trials collected comparator component Consent coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 patient creatinine creatinine) CRP database death diagnosis of COVID-19 died discharge dissemination domains doubling Effect EGFR Ejection fraction element eligible Endpoint enrolment Estimated Ethnicity evaluate event exclusion criteria feasibility Follow-up followed by General Hospital greater groups Health Health Organization heart failure high blood pressure highest hospital ICU ICU admission immunopathology include Inclusion inclusion and exclusion criteria increase increase in Increases indicate Infection inhibitor inhibitors initial initiated intervention arm intravenous invasive ventilation list Lower lowest lymphocyte Lymphocyte count lymphocyte counts mathematical mathematical model McGill University mean rank mechanical ventilation medical history medication medications meet Montreal Mortality number objective Older open open label Ordinal Scale outcome outcomes participant Participants past medical history Patient patient cohort PCR performed Prevent primary end point primary endpoint Protein protocol provided RAAS RAAS inhibitor random number generator randomised randomised controlled trial randomization Randomized Randomized controlled trial recruitment reduced Registration Renin required Sample Sample size SARS- CoV2 secondary secondary endpoint sensitivity sensitivity analysis serum creatinine Sex short term stability statistical power calculations status stroke study participant Study protocol subsequent supplementary material System table team the patient the primary endpoint therapy transfer transferred Treatment Trial troponin Version Victoria ward website were excluded WHO withdrawn World Health Organization
[DOI] 10.1186/s13063-021-05080-4 PMC 바로가기 [Article Type] Study Protocol

COVID-19 Encephalopathy in Adults

Internal Medicine

Published on 2021-02-012022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 48 hour Admission age angiotensin-converting enzyme 2 appear Asymptomatic Autoimmune baseline binding Care cause Cognitive impairment cognitive impairment in covid-19 COVID-19 COVID-19 illness Dementia Encephalopathy endothelial exhibited Fever groups Hospitalized hospitalized COVID-19 patient hypoxia influenza-like illness information ischemic injury Local Mild myalgia neurological manifestation neurological manifestations notable Pathogenesis pathophysiology Patient patients with COVID-19 PCR test polymerase chain positive presenting proinflammatory Remdesivir Respiratory illness respiratory symptom returned SARS-CoV-2 SARS-CoV-2 virus scale Symptom symptomatic the patient therapy thrombosis Treatment Vascular virus was done
[DOI] 10.7759/cureus.13052 PMC 바로가기 [Article Type] Internal Medicine

Characterization of pulmonary impairment associated with COVID-19 in patients requiring mechanical ventilation

Original Article

Published on 2021-01-012022-10-29
Journal: Revista Brasileira de Terapia Intensiva [Category] COVID-19,