Correlation of Immunogenicity and Reactogenicity of BNT162b2 and CoronaVac SARS-CoV-2 VaccinesBNT162b2와 CoronaVac SARS-CoV-2 백신의 면역원성과 반응성의 상관관계Article Published on 2022-04-272022-09-12 Journal: mSphere [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI 95% confidence interval adverse event AEs analyzed Antibody Response antibody response against BNT162b2 BNT162b2 vaccine CoronaVac correlation COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine Day Efficacy elicit female females Fever Frequency Gender geometric mean titer GMT headache Health help immunogenicity Infection injection site injection site pain itching joint Live virus local reaction male males men microneutralization Neutralizing Neutralizing antibodies neutralizing antibody of BNT162b2 Pain pandemic participant population immunity reactogenicity receiving recorded SARS-CoV-2 Side effect Side effects tiredness vaccination Vaccine Vaccine hesitancy Vaccines was determined while women [DOI] 10.1128/msphere.00915-21 PMC 바로가기 [Article Type] Article
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2Omicron SARS-CoV-2에 대한 BNT162b2 백신 2~3회 중화 및 내구성Article Published on 2022-04-132022-09-11 Journal: Cell Host & Microbe [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Antibody neutralization BNT162b2 BNT162b2 mRNA vaccine BNT162b2 vaccine dose effective geometric mean geometric mean titer GMT GMTs neutralization neutralization durability neutralize of BNT162b2 omicron Pfizer Pfizer vacine SARS-CoV-2 serum spike glycoprotein Support tested USA-WA1/2020 vaccinated individual vaccinated individuals Vaccination strategy variants virus viruses wild-type wild-type SARS-CoV-2 [DOI] 10.1016/j.chom.2022.02.015 PMC 바로가기 [Article Type] Article
Evaluation of Immunogenicity by Pseudovirus Neutralization Assays for SARS-CoV-2 Variants after Primary and Booster Immunization1차 및 추가 접종 후 SARS-CoV-2 변이체에 대한 슈도바이러스 중화 분석에 의한 면역원성 평가Article Published on 2022-04-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] baseline blood sample Blood samples booster booster dose collected COVID-19 COVID-19 vaccine determine disease dose Effectiveness enrolled evaluate Follow-up geometric mean geometric mean titer geometric mean titers GMT GMTs immune response immune responses immunization immunogenicity IMPROVE inactivated Inactivated COVID-19 vaccine instance NAb NAbs neutralization Neutralizing antibodies neutralizing antibody other variant other variants participant Participants peaked Primary and booster immunization Pseudovirus neutralization assay Pseudovirus neutralization assays reached Research SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants second dose seroconversion rate seroconversion rates Spike protein status strain the spike protein the vaccine titers vaccination variant variants were measured within 6 months Wuhan Wuhan-Hu-1 [DOI] 10.1016/j.ijid.2022.01.068 PMC 바로가기 [Article Type] Article
Sub-optimal neutralisation of omicron (B.1.1.529) variant by antibodies induced by vaccine alone or SARS-CoV-2 Infection plus vaccine (hybrid immunity) post 6-months6개월 후 백신 단독 또는 SARS-CoV-2 감염 + 백신(하이브리드 면역)에 의해 유도된 항체에 의한 오미크론(B.1.1.529) 변이체의 차선 중화Article Published on 2022-04-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Against Anti-RBD IgG antibody B.1.1.529 BBV152 Biotechnology ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine correlation Covaxin Covishield cross-sectional cross-sectional study demonstrated Department exhibited explain foundation four group four groups geometric mean geometric mean titre GMT group groups hybrid Hybrid immunity Immune escape Immunity inactivated India individual Infection limit Live virus Live-virus neutralisation Melinda Gate Melinda Gates moderate natural infection nCoV neutralisation neutralisation assay neutralisation test neutralisation titre Neutralisation titres neutralise neutralising ability omicron Omicron variant outcome Primary outcome quantification Rapid reduction reduction in SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 variant serum Significant Spread subjects tested titre USA vaccinated individual vaccinated individuals vaccination Vaccine variant virus Virus neutralisation [DOI] 10.1016/j.ebiom.2022.103938 PMC 바로가기 [Article Type] Article
Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials건강한 성인에서 코로나백 3차 접종의 면역원성 및 안전성, 2회 접종 일정의 면역 지속성: 2건의 단일 센터, 이중 맹검, 무작위, 위약 대조 임상 2상 임상 시험의 중간 결과Clinical Trial Published on 2022-04-012022-09-12 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 1:1 95% CI Abstract Administered Adverse reaction analysed antibody Antibody titre assigned Beijing booster dose China clinical trial clinical trials Cohort cohorts Concentration CoronaVac country Cutoff declined development dose doses double-blind eligible foundation GenBank accession number generate geometric geometric mean titre GMIs GMT GMTs groups healthy immune memory immune persistence immune response immunogenicity Inactivated vaccine increase increase in injection Jiangsu material natural neutralising antibody neutralising antibody titre Older outcome participant per-protocol population phase 2 trial Placebo placebo group placebo-controlled positive Program protocol amendment randomised Randomly recalled receive Registered reported resulting SARS-CoV-2 Science second dose Serious Adverse Event seropositive severity significantly increased technology threshold translation Trial vaccination vaccination against COVID-19 vaccination schedule Vaccine virus strain [DOI] 10.1016/S1473-3099(21)00681-2 PMC 바로가기 [Article Type] Clinical Trial
BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant RecipientsBNT162b2 3차 부스터 용량은 신장 이식 수혜자의 RBD IgG 및 중화 항체 모두에 의해 평가된 체액 반응을 상당히 증가시킵니다Article Published on 2022-03-212022-09-11 Journal: Transplant International [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Allograft antibody Antibody Response BNT162b2 BNT162b2 vaccine booster COVID-19 COVID-19 vaccine develop Diabetic diabetic nephropathy Dilution domain dose effective ESRD geometric mean geometric mean titer geometric mean titers GMT GMTs group had no humoral Humoral response IgG Immunosuppression increase independent predictor independent predictors mycophenolic acid negative and positive nephropathy Neutralizing antibodies neutralizing antibody non-responder non-responders of BNT162b2 Patient positive predictor pseudo-virus RBD RBD IgG Receptor-binding domain recipient recipients remained renal Renal transplantation Responder responders response response rate SARS-CoV-2 secondary to seroconverted significant increase stratified systemic systemic AEs the vaccine Transplant Vaccine were recorded [DOI] 10.3389/ti.2022.10239 PMC 바로가기 [Article Type] Article
Immune response to one dose of BNT162b2 mRNA Covid-19 vaccine followed by SARS-CoV-2 infection: An Italian prospective observational studyObservational Study Published on 2022-03-152022-10-05 Journal: Vaccine [Category] COVID19(2023년), SARS, 임상, [키워드] anti-SARS-CoV-2 Antibody Response Biological biological risk BNT162b2 mRNA vaccine carried categories control group COVID-19 dose European country first dose geometric mean titer GMT HCW HCWs Health healthcare worker Healthcare workers immunization immunized individual Infection initiated Italian Italy mRNA Observational cohort study of BNT162b2 positive PPE prospective observational study risk SARS-CoV-2 serological statistically significant difference surveillance data tested the antibody response the vaccine Two-arm vaccination Vaccinations Vaccine vaccine group was determined were infected [DOI] 10.1016/j.vaccine.2022.02.002 PMC 바로가기 [Article Type] Observational Study
Three doses of an inactivation-based COVID-19 vaccine induces cross-neutralizing immunity against the SARS CoV-2 Omicron variant비활성화 기반 COVID-19 백신의 3회 용량은 SARS CoV-2 Omicron 변이체에 대한 교차 중화 면역을 유도합니다Coronaviruses Published on 2022-03-032022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.1.529 collected coronavirus COVID-19 vaccine cross-neutralizing delta variant demonstrated dose enrolled fold geometric mean geometric mean titer geometric mean titers GMT immune Immunity immunization immunized induce natural infection neutralization activity Neutralizing activity neutralizing antibody omicron Omicron variant positive prototype pseudotyped Pseudotyped virus recipient reported respiratory SARS CoV SARS CoV-2 SARS-CoV-2 sera serum sample serum samples severe acute respiratory syndrome Coronavirus sustained the vaccine vaccination Vaccine variant was determined [DOI] 10.1080/22221751.2022.2044271 PMC 바로가기 [Article Type] Coronaviruses
Effect of an exercise bout before the booster dose of an inactivated SARS-CoV-2 vaccine on immunogenicity in immunocompromised patients비활성화된 SARS-CoV-2 백신의 추가 접종 전 운동 시합이 면역 저하 환자의 면역원성에 미치는 영향Randomized Controlled Trial Published on 2022-03-012022-09-12 Journal: Journal of applied physiology (Bethesda, Md. : 198 [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] anti-SARS-CoV-2 assigned booster booster dose comparable consecutive patient control group COVID-19 COVID-19 vaccine Effect ENhance exercise exhibited Frequency geometric mean titer GMT group homologous IgG immunized Immunocompromised patient immunogenicity Immunosuppression in both groups inactivated Inactivated vaccine intervention group NAb activity Neutralizing antibodies neutralizing antibody occurred Patient performed physical physical activity positive randomized controlled study remained resistance exercise resistance exercise. S1/S2 SARS-CoV-2 SARS-CoV-2 vaccine selected serology Sinovac-CoronaVac spondyloarthritis tested the vaccine vaccination [DOI] 10.1152/japplphysiol.00015.2022 PMC 바로가기 [Article Type] Randomized Controlled Trial
Association between physical activity and immunogenicity of an inactivated virus vaccine against SARS-CoV-2 in patients with autoimmune rheumatic diseasesClinical Trial Published on 2022-03-012022-10-05 Journal: Brain, behavior, and immunity [Category] SARS, 임상, [키워드] anti-SARS-CoV-2 ARD ARD patient ARD patients Autoimmune benefit cluster analysis coronavirus covariates defined ENhance exercise exhibited Frequency geometric mean titer GMT greater IgG Immunocompromised patients immunogenicity inactivated Inactivated vaccine inactive individual less lifestyle median Neutralizing activity neutralizing antibody Open-label Patient physical physical activity physically prospective cohort study questionnaire rheumatic disease S1/S2 SARS-CoV-2 SARS-CoV-2 vaccine Sedentary behavior seroconversion rate single-arm Trial vaccination Vaccine virus were assessed [DOI] 10.1016/j.bbi.2021.12.016 PMC 바로가기 [Article Type] Clinical Trial