Monitoring of SARS-CoV-2 seroprevalence among primary healthcare patients in the Barcelona Metropolitan Area: the SeroCAP sentinel network protocol바르셀로나 수도권의 1차 의료 환자 사이의 SARS-CoV-2 혈청 유병률 모니터링: SeroCAP 센티넬 네트워크 프로토콜Article Published on 2022-02-092022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] age age and sex Algorithm Analysis antibody approval Area association Barcelona biological sample biological samples blood sample Blood samples Characteristics Cluster cluster analysis collected confirmed case COVID-19 COVID-19 pandemic cross-sectional cross-sectional study Department distribution Epidemiology Ethical approval Ethics Factor Final final analysis Forming foundation framework Health care health department healthcare hospital Informed consent lab Logistic regression measure monitoring network Patient peer-reviewed performed primary care Primary Health Care protocol public health recommendation report required resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 seroprevalence SARS-CoV-2 trimeric spike protein Seroprevalence serum serum IgG antibodies serum IgG antibody Sex Spike protein submitted surrogate Trimeric spike protein university was obtained [DOI] 10.1136/bmjopen-2021-053237 PMC 바로가기 [Article Type] Article
Influence of the Delta Variant and Vaccination on the SARS-CoV-2 Viral LoadSARS-COV-2 바이러스 부하에 대한 델타 변종 및 예방 접종의 영향Article Published on 2022-02-042022-09-01 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] age and sex Alpha assays conducted COVID-19 Delta delta variant diagnosed dose doses Evolution Host Infection infections influence lead load nasopharyngeal Patient Prospective Study reducing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA single center Symptom symptom onset Symptoms the SARS-CoV-2 Thermo Fisher university vaccination Vaccination Status variant variants Viral Viral load viral spread virus were assessed were recorded [DOI] 10.3390/v14020323 PMC 바로가기 [Article Type] Article
T-cell immune response after mRNA SARS-CoV-2 vaccines is frequently detected also in the absence of seroconversion in patients with lymphoid malignanciesmRNA SARS-CoV-2 백신 후 T 세포 면역 반응은 림프 악성 종양 환자에서 혈청 전환이 없는 경우에도 자주 감지됩니다Clinical Trial Published on 2022-02-012022-09-12 Journal: British Journal of Haematology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] absence affected age and sex Analysis anti-cancer treatment anti-CD20 Anti-CD20 antibodies Anti-CD20 antibody anti-CD20 treatment antibody B-cell lymphoma cellular Chemotherapy treatment Complete conducted COVID-19 Diagnosis evaluated healthy subject Humoral response immune immune response Immunoglobulin increased mortality independent predictor lowest lymphoid lymphoid malignancies. lymphoma maintain malignancies malignancy Measures mRNA mRNA vaccination Multiple myeloma Patient Prospective Study Protective raise receiving Result SARS-CoV-2 vaccine Seroconversion seroconversion rate serological serological response seronegative patient subgroup of patient T-cell T-cell immune response T-cell Response Treatment vaccination [DOI] 10.1111/bjh.17877 PMC 바로가기 [Article Type] Clinical Trial
Access to eye care during the COVID-19 pandemic, IndiaResearch Published on 2022-02-012022-10-27 Journal: Bulletin of the World Health Organization [Category] COVID-19, [키워드] access age and sex assessment Care Community coronavirus disease COVID-19 COVID-19 pandemic Decline eye female finding First wave India less objective Older ophthalmic Outpatient pandemic proportion reduce required second wave significantly higher significantly lower used data [DOI] 10.2471/BLT.21.286368 PMC 바로가기 [Article Type] Research
Access to eye care during the COVID-19 pandemic, IndiaResearch Published on 2022-02-012022-10-27 Journal: Bulletin of the World Health Organization [Category] Coronavirus, COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] access age and sex assessment Care Community coronavirus disease COVID-19 COVID-19 pandemic Decline eye female finding First wave India less objective Older ophthalmic Outpatient pandemic proportion reduce required second wave significantly higher significantly lower used data [DOI] 10.2471/BLT.21.286368 PMC 바로가기 [Article Type] Research
Seek COVER: using a disease proxy to rapidly develop and validate a personalized risk calculator for COVID-19 outcomes in an international networkResearch Published on 2022-01-302022-10-28 Journal: BMC Medical Research Methodology [Category] COVID-19, Fulltext, SARS, [키워드] age and sex aggregate analyzed AUC calculator calibrated calibration Cancer chronic obstructive cohorts collected country covariate COVID-19 COVID-19 diagnosis COVID-19 patient COVID-19 patients data-driven database death demonstrated develop diabetes disease Diseases electronic medical record Estimated fatality Features flu-like symptom Hospital admission Hospitalization hyperlipidemia hypertension Influenza Intensive International investigated Kidney disease less Logistic regression outcome outcomes pandemic Patient Patient-level prediction modelling patients with influenza Pneumonia predictor pulmonary disease Research Result risk risk score South Korea Spain supplementary material symptom severity tested The United States transferred utility were used [DOI] 10.1186/s12874-022-01505-z PMC 바로가기 [Article Type] Research
Human genetic and immunological determinants of critical COVID-19 pneumoniaReview Published on 2022-01-282022-10-05 Journal: Nature [Category] 변종, 유전자 메커니즘, 진단, [키워드] age and gender age and sex auto-antibody autosomal cellular childhood COVID-19 Critical deficiencies determinant explained FIVE Genetic greater Host Human IFNs IFNα IFNβ Immunity immunological Inborn error individual Infection men molecular Neutralizing older patients Patient plasmacytoid dendritic cells Pneumonia proportion respiratory epithelial cell respiratory tract risk of death SARS-CoV-2 SARS-COV-2 infection Spread systemic inflammation TLR3 TLR7 Trigger Type I IFN type I interferon virus women younger patients [DOI] 10.1038/s41586-022-04447-0 [Article Type] Review
Is There a Crucial Link Between Vitamin D Status and Inflammatory Response in Patients With COVID-19?COVID-19 환자의 비타민 D 상태와 염증 반응 사이에 중요한 연관성이 있습니까?Clinical Trial Published on 2022-01-242022-09-12 Journal: Frontiers in Immunology [Category] 임상, 진단, [키워드] 25OHD 25OHD level 25OHD levels adjusted age and sex biochemical Clinical data cohort of patient Complete consecutive patient coronavirus disease correlation COVID-19 CRP Cytokine storm D-dimer Effect evaluate evaluated group hospital Hospitalization hypovitaminosis Hypovitaminosis D IL-10 IL-6 Infection Inflammatory marker inflammatory markers inverse correlation management marker non-survivor P/F ratio Patient patients Pneumonia poor prognosis prevalent response Result risk factor SARS-CoV-2 secondary endpoint severe ARDS severity significantly higher status suggested the disease TNF-α Vitamin D Vitamin D status with COVID-19 [DOI] 10.3389/fimmu.2021.745713 PMC 바로가기 [Article Type] Clinical Trial
Variation in excess all-cause mortality by age, sex, and province during the first wave of the COVID-19 pandemic in ItalyArticle Published on 2022-01-202022-10-29 Journal: Scientific Reports [Category] Coronavirus, SARS, [키워드] age age and sex all-cause mortality country COVID COVID-19 COVID-19 pandemic death develop diagnostic distribution Epidemiology Evidence Fatality rate First wave Infection Infectious diseases intensity Italy Mortality occurred pandemic Population public health rapid response Registered Sex Transmission [DOI] 10.1038/s41598-022-04993-7 PMC 바로가기 [Article Type] Article
B- and T-Cell Responses After SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis Receiving Disease Modifying Therapies: Immunological Patterns and Clinical ImplicationsClinical Trial Published on 2022-01-172022-10-04 Journal: Frontiers in Immunology [Category] 임상, 치료기술, [키워드] acute respiratory syndrome administration age and sex All the patient Analysis anti-S anti-S antibody Antibody detection Antibody titers B-lymphocyte blood lymphocyte count CD20 cell-mediated response characterized circulating clinical Cohort comparable coronavirus Coronavirus-2 correlation COVID COVID-19 disease dose effective enrolled evaluate fingolimod General population GraphPad Prism healthy donor help Humoral response IFN-gamma IGRA Immunological response increase in lymphocyte Modifying mRNA vaccine Multiple multiple sclerosis Natalizumab NK-cell Ocrelizumab Patient pattern peptide peptides peripheral Peripheral blood Population protective role raised reduced reduction reported response Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine sclerosis second dose severe COVID-19 Spread symptoms of COVID-19 T-cell T-cell Response T-cell responses T-lymphocyte Treatment Vaccination strategy Vaccine vaccine immunogenicity was performed were assessed while [DOI] 10.3389/fimmu.2021.796482 PMC 바로가기 [Article Type] Clinical Trial