CATH: increased structural coverage of functional spaceAcademicSubjects/SCI00010 Published on 2021-01-082022-10-31 Journal: Nucleic Acids Research [Category] Coronavirus, [키워드] addition annotation annotations assigned Cancer concomitant increase Coverage displaying domain domains driver family functional GO term identify increase information predicted Protein protein sequence provided SARS-CoV-2 proteins sequence significantly Structure subset Variation [DOI] 10.1093/nar/gkaa1079 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
Europe PMC in 2020AcademicSubjects/SCI00010 Published on 2021-01-082022-10-31 Journal: Nucleic Acids Research [Category] Coronavirus, MERS, [키워드] Abstract abstracts added annotation API article articles curated database Europe experimental protocols feature include offer peer-reviewed platform PMC PubMed abstract Research resource resources significantly unique website [DOI] 10.1093/nar/gkaa994 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
UniProt: the universal protein knowledgebase in 2021AcademicSubjects/SCI00010 Published on 2021-01-082022-10-31 Journal: Nucleic Acids Research [Category] Coronavirus, [키워드] adopted annotation automated Community Completeness contribute COVID-19 pandemic functional information Protein protein sequence proteome provided reduce Research resource sequence submission UniProt [DOI] 10.1093/nar/gkaa1100 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
The UCSC Genome Browser database: 2021 updateUCSC 게놈 브라우저 데이터베이스: 2021년 업데이트AcademicSubjects/SCI00010 Published on 2021-01-082022-09-10 Journal: Nucleic Acids Research [Category] MERS, 유전자 메커니즘, [키워드] added annotation Community coronavirus database display elements ENCODE feature gene annotation gene annotations Genome genome browser Genomics heatmap Improvements include Matched NCBI New outbreak promoter promoters provided RefSeq released required Research RNA the SARS-CoV-2 Trio UCSC Genome Browser VCF files [DOI] 10.1093/nar/gkaa1070 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
GENCODE 2021젠코드 2021AcademicSubjects/SCI00010 Published on 2021-01-082022-09-10 Journal: Nucleic Acids Research [Category] MERS, 유전자 메커니즘, [키워드] Analysis annotation automated bioinformatics completion convergence creation database Ensembl Genome high accuracy improvement Improvements resource SARS-CoV-2 SARS-COV-2 infection Structure Support supported transcript transcripts UCSC Genome Browser [DOI] 10.1093/nar/gkaa1087 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
ViruSurf: an integrated database to investigate viral sequencesViruSurf: 바이러스 서열을 조사하기 위한 통합 데이터베이스AcademicSubjects/SCI00010 Published on 2021-01-082022-09-10 Journal: Nucleic Acids Research [Category] MERS, 변종, [키워드] addition Amino acid annotation attribute attributes COG-UK collected complex condition curated database Dengue described dimensions Ebola example expressing faster GenBank heterogeneous humans IMPROVE MERS-CoV Metadata nucleotide offer outbreak pandemic populations RefSeq Research response resulting SARS-CoV SARS-CoV-2 selected sequence sequences subset threat variants Viral viral sequence viral sequences virus viruses [DOI] 10.1093/nar/gkaa846 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysisResearch Paper Published on 2021-01-012022-10-29 Journal: International Journal of Medical Sciences [Category] COVID-19, MERS, [키워드] A549 ACE2 acute respiratory distress acute respiratory syndrome alteration Analysis angiotensin-converting enzyme 2 annotation applied approach bioinformatics caused cells clinical manifestation complement contribute controls coronavirus CoV COVID-19 CoVs current diagnose disease distress dysregulation effective enrichment epithelial exacerbate Gene Expression Gene ontology gene signature Genetic host cell immune system in silico induce Infection Ingenuity Pathway Analysis interferon kill Lung epithelial cells medication NHBE overexpression pandemic pathogenic coronavirus pathway Pathways performed receptor signaling Research response RNA-sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cell severely ill patients syndrome target upregulated gene Venn diagram Visualization were infected [DOI] 10.7150/ijms.52256 PMC 바로가기 [Article Type] Research Paper
The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humansSARS-CoV-2 ORF10은 인간의 시험관 내 또는 생체 내에서 필수적이지 않습니다.Research Article Published on 2020-12-102022-08-13 Journal: PLoS Pathogens [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] accessory proteins analyses annotation appear Author can not coding region debate described disease downstream Evidence expressed expression Genome genomic genomic sequence Human humans hypothetical hypothetical protein in vitro in vitro study in vivo include infected with SARS-CoV-2 Initially Innate immunity Laboratory laboratory analyses mRNA mRNAs N gene observation Open reading frame open reading frames ORF10 ORF10 protein ORFs Pathogenesis Patient positioned produced Protein protein-coding gene Proteins related virus related viruses replicated Replication required SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variant SARS-CoV-2 variants sequence homology sequence similarity strain Strains structural protein structural proteins subgenomic mRNA subgenomic mRNAs the SARS-CoV-2 genome Transmissibility treated two patients variant Viral Viral proteins viruses while [DOI] 10.1371/journal.ppat.1008959 PMC 바로가기 [Article Type] Research Article
An Educational Bioinformatics Project to Improve Genome AnnotationMicrobiology Published on 2020-12-072022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] Amino acid Analysis annotation approach automated Bacterial binding bioinformatics can be used cells cellular characterization classroom Complete Course database detect determine Differential gene expression domains education Enough Evidence example experimental evidence functions Genome genome annotation help hypothetical hypothetical protein identify IMPROVE include knowledge lack ligands mRNA expression Open reading frame Phylogenetic predict Program Protein Proteins provide random resource sequence sequence similarity student Support training video Undergraduate variety while X-ray crystallography YouTube [DOI] 10.3389/fmicb.2020.577497 PMC 바로가기 [Article Type] Microbiology
The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactionsBioGRID 데이터베이스: 선별된 단백질, 유전 및 화학적 상호작용의 포괄적인 생물의학 자원Tools for Protein Science Published on 2020-11-232022-09-10 Journal: Protein Science : A Publication of the Protein Soc [Category] MERS, SARS, 변종, [키워드] acute respiratory syndrome addition annotation BioGRID Biological biological network Biomedical research build can be used captures carried Cas9 cause cell lines cellular chemical interaction Community Complex network Complex networks COVID‐19 COVID‐19 CRISPR CRISPR screen CRISPR Screens curated database dataset datasets disease drug target drugs example experimental evidence extension facilitate generate Genetic genetic interaction genetic interactions genetic screens Health Human include Interaction interactions Modification mouse open organism phenotype post‐translational modification Protein protein interaction Regulation resource respiratory SARS‐CoV‐2 virus Screen Severe acute respiratory syndrome single mutant small molecule Small molecules species specific disease ubiquitin‐proteasome system worm yeast [DOI] 10.1002/pro.3978 PMC 바로가기 [Article Type] Tools for Protein Science