Nanomechanical analysis of SARS-CoV-2 variants and predictions of infectiousness and lethalityArticle Published on 2022-08-102022-11-16 Journal: Soft matter [Category] SARS, 변종, [키워드] Alpha variant Analysis approach B.1.351 B.1.617.2 Beta cause circulation COVID-19 D614G D614G mutation delta variant Effect epidemiological estimate explain higher infectivity interactions less Lineage Lineage B.1.1.7 molecular mutate Mutation offer pathogen pathway predict predicted Predictive Prevalence SARS-CoV-2 variant spike mutation Spike protein Spread strain variant variants virus virus spike protein viruses [DOI] 10.1039/d1sm01181b PMC 바로가기
Characterization of the SARS-CoV-2 B.1.621 (Mu) variantSARS-CoV-2 B.1.621(Mu) 변종 특성화Article Published on 2022-08-102022-09-11 Journal: Science Translational Medicine [Category] SARS, 변종, 진단, [키워드] Antibody neutralization Antibody titer Antibody titers B.1.351 B.1.351, Beta B.1.621 Beta Beta variant characterization convalescent serum hamster hamsters Health Organization immune response individual Infection Live virus Moderna mRNA vaccines neutralization Neutralization assay neutralized Neutralizing antibody titer Pfizer/BioNTech reduced reduction SARS-CoV-2 second vaccination sensitivity serum serum sample serum samples subsequent the SARS-CoV-2 variant World Health Organization [DOI] 10.1126/scitranslmed.abm4908 PMC 바로가기 [Article Type] Article
Interferon resistance of emerging SARS-CoV-2 variants새로운 SARS-CoV-2 변이체의 인터페론 내성Article Published on 2022-08-092022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제, [키워드] (Alpha) (Beta) Alpha B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta Course COVID-19 COVID-19 pandemic Critical driving ENhance exhibited FIVE highlight implication include infections Innate immunity interferon interferon response interferons isolates lethality limit lineages Mutation neutralizing antibody outbreak P.1 Pathogenesis potency responses SARS-CoV-2 SARS-CoV-2 evolution SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants spike spike mutations subtype the interferon Transmissibility Treatment Vaccine variant variants variants of concern Viral viral gene viral genes viral lineage virus infectivity while [DOI] 10.1073/pnas.2203760119 PMC 바로가기 [Article Type] Article
A pyrosequencing protocol for rapid identification of SARS-CoV-2 variantsSARS-CoV-2 변이체의 신속한 식별을 위한 파이로시퀀싱 프로토콜Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] (Alpha) (Beta) acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha B.1.1 B.1.1.529 B.1.1.7 B.1.351 B.1.525 B.1.617.1 B.1.617.2 B.1.621 Beta circulating circulating variant circulating variants confidence Coronaviridae coronavirus costly Delta differentiation distribution effort Epsilon Eta Gamma geographical regions information Iota lineages MONITOR monoclonal antibody monoclonal antibody therapies monoclonal antibody treatment Mutation Next-generation sequencing NGS omicron Patient protocol pyrosequencing reported respiratory reverse transcription SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 variant Sequencing Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Spike protein Surveillance the United State therapy time-consuming United States variant variants [DOI] 10.1002/jmv.27770 PMC 바로가기 [Article Type] Article
Early detection and surveillance of SARS-CoV-2 genomic variants in wastewater using COJACCOJAC을 사용한 폐수 내 SARS-CoV-2 게놈 변이체의 조기 탐지 및 감시Article Published on 2022-08-012022-09-11 Journal: Nature Microbiology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Alpha Alpha variant application B.1.1.7 B.1.351 Beta bioinformatics clinical samples computational analysis delta variant detect Early detection epidemiological epidemiological surveillance estimate fitness Gamma genomic sequencing genomic variant Local local spread MONITOR Mutation National outbreak P.1 population level Precision Prevalence quantification replicate reported robust SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Sequencing sequencing data Spread Surveillance Switzerland Transmission variant variants variants of interest variants of SARS-CoV-2 wastewater while [DOI] 10.1038/s41564-022-01185-x PMC 바로가기 [Article Type] Article
Neutralizing antibody activity against 21 SARS-CoV-2 variants in older adults vaccinated with BNT162b2BNT162b2 백신을 접종한 노인의 21개 SARS-CoV-2 변이체에 대한 항체 활성 중화Article Published on 2022-08-012022-09-11 Journal: Nature Microbiology [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] Adults analysed antibody Antibody responses antigenic Antiviral B.1.1.529 B.1.351 B.1.617.2 Beta BNT162b2 Booster vaccine booster vaccines change clinically Cohort COVID-19 disease cross-protection Delta detectable disease domain dose Effectiveness elicit enzyme enzyme-linked immunosorbent assays examined group individual individuals median mitigate neutralization Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses neutralizing antibody titre neutralizing antibody titres of BNT162b2 Older Older adults omicron Pfizer-BioNTech pseudotype RBD responsible SARS-CoV-2 SARS-CoV-2 immunity SARS-CoV-2 neutralizing antibody SARS-CoV-2 variant SARS-CoV-2 variants sera serious COVID-19 Spike protein Spike proteins spike variants titre Vaccine vaccine dose variant variants wildtype [DOI] 10.1038/s41564-022-01163-3 PMC 바로가기 [Article Type] Article
Epidemiological profile of COVID-19 in the French overseas department Mayotte, 2020 to 2021Article Published on 2022-08-012022-11-16 Journal: Eurosurveillance [Category] SARS, 변종, 치료기술, [키워드] Admission B.1.351 Beta Beta variant COVID-19 COVID-19 outbreak COVID-19 pandemic Critical epidemiological Epidemiology First wave French Health hospital hospitalisation ICU incidence rate increase in Indian Ocean Inflammatory Laboratory Local Mayotte measure Mortality multi-systemic inflammatory syndromes National New pangolin patients PCR peaked positive SARS-CoV-2 second wave Seven Severe case severity Surveillance Testing Transmissibility variant Virological [DOI] 10.2807/1560-7917.ES.2022.27.34.2100953 PMC 바로가기
Comparative characterization of antibody responses induced by Ad5-vectored spike proteins of emerging SARS-CoV-2 VOCs신흥 SARS-CoV-2 VOC의 Ad5 벡터 스파이크 단백질에 의해 유도된 항체 반응의 비교 특성화Comparative Study Published on 2022-07-292022-09-11 Journal: Signal Transduction and Targeted Therapy [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] administration Alpha analyzed antibody Antibody Response Antibody responses B.1.351 B.1.429 B.1.617.2 Beta booster Characteristics Comparative cross-neutralizing antibody cross-reactivity Delta Effects elicit elicited Epsilon Gamma Heterologous immune response immune responses Lineage mice Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing antibody responses omicron other variant other variants pandemic produced provided regimens responses against SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Single-dose spike Spike protein Spike proteins Spread stimulate the SARS-CoV-2 the vaccine unique vaccination Vaccination strategy Vaccine Vaccine development variants VoC VOCs [DOI] 10.1038/s41392-022-01065-0 PMC 바로가기 [Article Type] Comparative Study
Six-Month Follow-Up of Immune Responses after a Rapid Mass Vaccination against SARS-CoV-2 with BNT162b2 in the District of Schwaz/AustriaSchwaz/Austria 지역에서 BNT162b2를 사용한 SARS-CoV-2에 대한 신속한 대량 백신 접종 후 면역 반응의 6개월 추적Article Published on 2022-07-272022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] age Analysis antibody Antibody Response B-cell response B.1.351 Beta BNT162b2 carried correlated COVID-19 detect District enrolment evaluate immune response immune responses Infection mass mass vaccination natural infection new SARS-CoV-2 no correlation outbreak participant participated preserved provide Rapid reduction in response robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections second dose Seropositivity Serum level serum levels specific antibodies spring study participant subject Support T cell T cell response T cell responses T-cell Response the District the SARS-CoV-2 vaccination variant waned was measured [DOI] 10.3390/v14081642 PMC 바로가기 [Article Type] Article
SARS-CoV-2’s Variants of Concern: A Brief CharacterizationSARS-CoV-2의 우려 변종: 간략한 특성Review Published on 2022-07-262022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha angiotensin angiotensin-2 converting enzyme B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta Cell Characteristics characterization coronavirus COVID-19 COVID-19 vaccination Defense Delta Gamma Genetic Host host cell host cell receptor Immune escape immune responses immunogenic modify Mutation N-terminal new SARS-CoV-2 omicron pandemic coronavirus promote raise RBD S protein SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus Spike protein variant variants variants of concern viral immune escape. virus virus transmissibility VoC VOCs [DOI] 10.3389/fimmu.2022.834098 PMC 바로가기 [Article Type] Review