C 60 fullerene against SARS-CoV-2 coronavirus: an in silico insightSARS-CoV-2 코로나바이러스에 대한 C 60 풀러렌: 실리코에 대한 통찰력Article Published on 2021-09-072022-09-10 Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 치료제, [키워드] 3CLpro accomplishment Analysis Applied mathematics binding binding mechanism binding pocket block carbon catalytic complex complexes computational method Computational methods Computational study coronavirus COVID-19 disease deaths Factor functions globe in silico inhibitory activity initial interact mechanisms molecular dynamics Molecular dynamics simulation Molecular medicine new SARS-CoV-2 pandemic potential mechanism Prevent protein targets RdRP RNA synthesis SARS-CoV-2 SARS-CoV-2 protein shown stability virus inhibition WHO widespread [DOI] 10.1038/s41598-021-97268-6 PMC 바로가기 [Article Type] Article
The Serum Metabolome of Moderate and Severe COVID-19 Patients Reflects Possible Liver Alterations Involving Carbon and Nitrogen MetabolismArticle Published on 2021-09-022022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] affecting alteration amino acid metabolism Analysis carbon Cohort complex coronavirus COVID-19 COVID-19 patient deaths disease severity dysregulation form hospitalized COVID-19 patients include Infection involved Involving lactic acid liver mass spectrometry metabolic pathway metabolism metabolome metabolomic analysis metabolomics Mild moderate nitrogen pandemic pathophysiology progression SARS-CoV-2 SARS-CoV-2 coronavirus serum serum cytokines Serum level Spread systemic effect the disease Variation [DOI] 10.3390/ijms22179548 PMC 바로가기 [Article Type] Article
Carbon nanomaterials as promising substrates in the design of sensors for SARS-CoV-2 and new emerging viral infectionsCommentary Published on 2021-08-252022-10-30 Journal: Nanomedicine [Category] COVID-19, MERS, SARS, [키워드] biosensors carbon carbon nanomaterials Carbon nanotube COVID-19 electrochemical Graphene Graphene oxide immunosensor optical nanosensor SARS-CoV-2 substrate viral infection [DOI] 10.2217/nnm-2021-0154 PMC 바로가기 [Article Type] Commentary
Recent Insights into the Measurement of Carbon Dioxide Concentrations for Clinical Practice in Respiratory MedicineReview Published on 2021-08-212022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, [키워드] Accuracy alveolar assessment Bland–Altman analysis Blood blood gas analysis capillary blood carbon carbon dioxide change children clinical Clinical practice Concentration dioxide end-tidal end-tidal partial pressure Endotracheal intubation estimate Frequency Gas exchange gold standard insight measure measurement mechanical ventilation Medicine metabolism Non-invasive obesity oxygen performed Practice provide Quotient recent reflect Regulation respiratory sleep apnea syndrome sleep disorders These data transcutaneous partial pressure Ventilation [DOI] 10.3390/s21165636 PMC 바로가기 [Article Type] Review
Medical conferences in the era of environmental conscientiousness and a global health crisis: The carbon footprint of presenter flights to pre-COVID pediatric urology conferences and a consideration of future options환경 의식과 글로벌 보건 위기 시대의 의료 컨퍼런스: 발표자가 코로나19 이전 소아 비뇨기과 컨퍼런스에 참석한 탄소 발자국과 미래 옵션에 대한 고려Review Published on 2021-08-012022-09-11 Journal: Journal of pediatric surgery [Category] SARS, 치료기술, 치료제, [키워드] Annual Canada carbon Carbon footprint Climate Climate change collected conferences COVID-19 COVID-19 pandemic detect distance ecological Ecological Footprint Europe Evidence generate global pandemic greenhouse gas emissions Health IQR knowledge Level majority median Medical conference medium meeting MOST North America Pairwise comparison pairwise comparisons pediatric pediatric urology presenter presenting reducing Research statistical significance the median Travel Urology USA variable was performed [DOI] 10.1016/j.jpedsurg.2020.07.013 PMC 바로가기 [Article Type] Review
Antiviral performance of graphene-based materials with emphasis on COVID-19: A reviewReview Article Published on 2021-05-252023-08-30 Journal: Medicine in Drug Discovery [Category] E형 간염, [키워드] carbon coronavirus COVID-19 Graphene surface interaction [DOI] 10.1016/j.medidd.2021.100099 PMC 바로가기 [Article Type] Review Article
Identification of tuna protein-derived peptides as potent SARS-CoV-2 inhibitors via molecular docking and molecular dynamic simulation분자 도킹 및 분자 역학 시뮬레이션을 통한 강력한 SARS-CoV-2 억제제로서의 참치 단백질 유래 펩타이드 식별Article Published on 2021-04-162022-09-11 Journal: Food chemistry [Category] SARS, 치료제, [키워드] ACE2 ACE2 binding Analysis Antiviral binding carbon Cys145 docking electrostatic interaction electrostatic interactions elicit GLN189 Glu166 Gly143 HIS164 His41 hydrogen Hydrogen bond hydrogen bonds identification identify inhibiting inhibitor inhibitory Interaction M pro M(pro) mechanism molecular molecular docking molecular docking analysis peptide peptides Protein Protein supplementation. receptor receptor ACE2 residue residues SARS-CoV-2 target targets Thr190 THR26 Virtual screening vital role vital roles was performed [DOI] 10.1016/j.foodchem.2020.128366 PMC 바로가기 [Article Type] Article
Identification of Anti-SARS-CoV-2 Compounds from Food Using QSAR-Based Virtual Screening, Molecular Docking, and Molecular Dynamics Simulation AnalysisArticle Published on 2021-04-132022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] Analysis carbon complementary Compound Consensus correlation COVID-19 development docking Dynamics food Genetic identification identify inhibitory inhibitory activity machine learning molecular molecular docking motif MPro nitrogen novel molecule protease provided QSAR QSAR-based virtual screening Quantitative R 2 Regression relationship SARS-CoV SARS-CoV-2 Screening similarity Simulation Simulation study stability statistical variant Virtual screening [DOI] 10.3390/ph14040357 PMC 바로가기 [Article Type] Article
Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patientsResearch Published on 2021-04-062022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] adopted applied carbon caused clinical cohort study collected Compliance conducted COVID-19 COVID-19 pandemic defined died dioxide Effect had more ICU ICU admission intensive care unit Intubated Invasive mechanical ventilation invasively ventilated patient Italian Limited majority mechanical ventilation mechanically ventilated patient Mild moderate Mortality multicentre National no difference Older outcome Oxygenation pandemic PaO Patient patients prone Prone position prone positioning Refractory hypoxemia Respiratory failure Respiratory system Result resulting severe ARDS severe disease severe respiratory failure significant increase significantly more subset supplementary material treat Ventilation ventilatory was collected was performed was reduced [DOI] 10.1186/s13054-021-03552-2 PMC 바로가기 [Article Type] Research
Estimating the minimum number of SARS-CoV-2 infected cases needed to detect viral RNA in wastewater: To what extent of the outbreak can surveillance of wastewater tell us?폐수에서 바이러스 RNA를 감지하는 데 필요한 SARS-CoV-2 감염 사례의 최소 수 추정: 폐수 감시를 통해 발병 정도를 알 수 있습니까?Article Published on 2021-04-012022-09-11 Journal: Environmental research [Category] SARS, 치료기술, 치료법, 치료제, [키워드] activated Activated sludge tank average carbon Community correlation COVID-19 Degradation detect detection Detection sensitivity early stage early stages Epidemiology Frequency hospital Hospitalized hospitalized patient hospitalized patients infected case instance instances knowledge Log reduction N1 and N2 Nucleocapsid gene outbreak parameter per day positive qPCR Quantitative quantitative PCR reduced required Reverse transcription quantitative PCR RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 RNA septic septic tank Surveillance TANK the SARS-CoV-2 total organic carbon Transcription treated Treatment Viral RNA virus wastewater Wastewater-based epidemiology water water quality [DOI] 10.1016/j.envres.2021.110748 PMC 바로가기 [Article Type] Article