Photoresponsive Inorganic Nanomaterials in OncologyReview Published on 2023-08-072024-09-05 Journal: Technology in cancer research & treatment [Category] update2024, [키워드] carbon magnetic hyperthermia Nanoparticles noble metals photodynamic therapy photothermal therapy Radiotherapy sonodynamic therapy [DOI] 10.1177/15330338231192850 PMC 바로가기 [Article Type] Review
Novel approach based on GQD-PHB as anchoring platform for the development of SARS-CoV-2 electrochemical immunosensorArticle Published on 2022-11-012022-11-15 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] addition analyzed antibodies antibody approach Blood carbon Carbon nanomaterial Concentration conditions coronavirus spike protein decrease develop domain Dot DPV Electrochemical devices Fever functional Graphene human serum Immunosensors construction. Interaction investigated matrix effect Modification novel PBS performed platform probe Protein provided pulse quantum RBD SARS-CoV-2 selective SEM serum shown was tested was used [DOI] 10.1016/j.aca.2022.340442 PMC 바로가기
Predicting Airborne Infection Risk: Association Between Personal Ambient Carbon Dioxide Level Monitoring and Incidence of Tuberculosis Infection in South African Health WorkersArticle Published on 2022-10-122022-11-15 Journal: Clinical Infectious Diseases: An Official Publicat [Category] 진단, [키워드] African ambient analyzed Annual baseline Cape carbon carbon dioxide monitoring CO2 coronavirus disease decrease demonstrated dioxide dose-dependent evaluate Health health worker health workers healthcare facility help hospital IGRA implication incidence increase in Increasing Infection infection control infection risk interferon-γ Intervention less Level likelihood Logistic regression median monitoring occur Odds ratio positive PPM Predictive QuantiFERON Quantitative random risk South South Africa subset threshold town Transmission Tuberculosis tuberculosis infection control (TB-IC). Ventilation worker [DOI] 10.1093/cid/ciac183 PMC 바로가기
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antiviralsSARS-CoV-2 항바이러스제로서의 알데히드 기반 트리펩티딜 주요 프로테아제 억제제의 다각적 평가Article Published on 2022-10-052022-09-11 Journal: European journal of medicinal chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] 293T cell 293T cells active site aldehyde Amino acid amino acids Antiviral antiviral potency binding carbon cellular complexes conducted covalent inhibitors COVID-19 crystal structure cysteine cytotoxicity develop enzyme exhibited expressed flexible high potency in vitro inhibit inhibitor inhibitors interact low potency M pro main protease N-terminal pathogen Previous studies previous study Pro protease Protease inhibitor residue residues SARS-CoV-2 selected Structural variation structures tolerable Toxicity Treatment treatment of COVID-19 Tripeptides. unnatural Variation X-ray [DOI] 10.1016/j.ejmech.2022.114570 PMC 바로가기 [Article Type] Article
Chalcone-amide, a privileged backbone for the design and development of selective SARS-CoV/SARS-CoV-2 papain-like protease inhibitors선택적인 SARS-CoV/SARS-CoV-2 파파인 유사 프로테아제 억제제의 설계 및 개발을 위한 특권적인 백본인 Chalcone-amideReview Published on 2022-10-052022-09-11 Journal: European journal of medicinal chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] active site acute respiratory syndrome acute respiratory syndrome coronavirus amide antiviral immune responses backbone binding carbon caused chalcone Chalcone amide (N-benzylbenzamide) complex Compound coronavirus COVID-19 COVID-19 pandemic Critical crystal structure effort functional Genetic Host immune responses in some increase Infection inhibitor inhibitors inhibitory potency introduced maturation methyl group Papain Papain-like protease Papain-like protease (PLpro) performed PLPro polyproteins protease Protein Regulation Replication reported Research SAR SARS-CoV SARS-CoV-2 Screening selective shown similarity Structure therapeutic agent therapeutic agents Treatment treatment of COVID-19 understanding unique X-ray X-ray crystal structure. [DOI] 10.1016/j.ejmech.2022.114572 PMC 바로가기 [Article Type] Review
Sensitive SARS-CoV-2 detection in wastewaters using a carbon nanodot-amplified electrochemiluminescence immunosensor탄소 나노도트 증폭 전기화학발광 면역센서를 사용한 폐수 내 민감한 SARS-CoV-2 검출Article Published on 2022-09-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, [키워드] antibody can be used carbon caused circulation Concentration construction contribute COVID-19 demonstrated detect ECL Electrochemiluminescence feasible functional group immunosensor limit of detection pandemic platform promote PROTECT Protein Public health interventions S1 protein SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 detection SARS-CoV-2 spike SARS-CoV-2 spike S1 protein sensitive specificity spike stability Support the SARS-CoV-2 utility virus virus detection wastewater [DOI] 10.1016/j.talanta.2022.123543 PMC 바로가기 [Article Type] Article
Carbon dioxide rises beyond acceptable safety levels in children under nose and mouth covering: Results of an experimental measurement study in healthy childrenRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: Environmental research [Category] 임상, [키워드] age ambient Appropriate automated average baseline breathing breathing frequency carbon carbon dioxide children CO(2) country covariate COVID-19 determine European face Face masks Health healthy children Inhaled Linear model Mask nose not significant pandemic physiological PPM provided pulse raise Randomized Randomized study. resting position Result seated sequence significant effect Spa Standard deviation surgical variables Ventilation was measured wearing were measured [DOI] 10.1016/j.envres.2022.113564 PMC 바로가기 [Article Type] Randomized Controlled Trial
Ultrasensitive SARS-CoV-2 diagnosis by CRISPR-based screen-printed carbon electrodeCRISPR 기반 스크린 인쇄 탄소 전극으로 초고감도 SARS-CoV-2 진단Article Published on 2022-08-152022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] carbon CeO(2) nanorods cleavage COVID-19 CRISPR CRISPR/Cas12a detection Detection sensitivity detection system Diagnosis diagnosis of SARS-CoV-2 reporter required SARS-CoV-2 SARS-CoV-2 detection Screen Screen-printed carbon electrode. ssDNA Viral load [DOI] 10.1016/j.aca.2022.340120 PMC 바로가기 [Article Type] Article
Determination of rSpike Protein by Specific Antibodies with Screen-Printed Carbon Electrode Modified by Electrodeposited Gold Nanostructures전착된 금 나노구조에 의해 변형된 스크린 인쇄된 탄소 전극이 있는 특정 항체에 의한 rSpike 단백질의 측정Article Published on 2022-08-032022-09-11 Journal: Biosensors [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 albumin antibodies antibody antigen–antibody complex applicability binding Blood bovine bovine serum albumin carbon changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cyclic voltammetry (CV) Determination differential pulse voltammetry (DPV) DPV electrochemical immunosensor electrochemical impedance spectroscopy (EIS) electrode electron transfer evaluated exhibit gold gold nanostructures (AuNS) heterogeneous Interaction L-cysteine limit limit of detection nanostructure nonspecific Patient Protein pulse quantification rate constant Research respiratory SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 virus self-assembled monolayer (SAM) serum serum albumin severe acute respiratory syndrome Coronavirus solution Specific specific antibodies specific antibody specificity spike Spike protein spike protein (Spike). Spike proteins surface area was performed was used were assessed [DOI] 10.3390/bios12080593 PMC 바로가기 [Article Type] Article
Label-free electrochemical aptasensor for rapid detection of SARS-CoV-2 spike glycoprotein based on the composite of Cu(OH) 2 nanorods arrays as a high-performance surface substrate고성능 표면 기판으로서 Cu(OH) 2 나노로드 어레이의 합성물을 기반으로 한 SARS-CoV-2 스파이크 당단백질의 신속한 검출을 위한 무표지 전기화학 앱타센서Article Published on 2022-08-012022-09-11 Journal: Bioelectrochemistry (Amsterdam, Netherlands) [Category] SARS, 치료기술, 치료제, [키워드] addition aptamer Aptamer-based sensors carbon Chain Reaction characterized Combination complexes copper Copper hydroxide nanorods COVID-19 cross-reactivity decrease Detection limit diffraction dynamic range Efficiency electrode electron microscopy electron transfer evaluated exhibited feasibility glycoprotein healthy individual high stability hydroxide immobilization lAbel Microscopy PCR polymerase chain polymerase chain reaction probe provided repeatability reproducibility Saliva SARS-CoV-2 SARS-CoV-2 spike glycoprotein Screen sensitivity sick spike spike glycoprotein transport medium Viral transport medium VTM was used X-ray X-ray diffraction [DOI] 10.1016/j.bioelechem.2022.108106 PMC 바로가기 [Article Type] Article