Flattening the Curve of COVID-19 Vaccine Rejection—An International OverviewArticle Published on 2021-01-132022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] anticipated China coronavirus disease coronavirus vaccine country COVID-19 COVID-19 vaccine Curve Czech Republic effort flattening General population herd immunity Immunity individual International mandatory much higher National normality Russia Safe supported the vaccine Turkey vaccination Vaccine hesitancy Vaccines [DOI] 10.3390/vaccines9010044 PMC 바로가기 [Article Type] Article
MicroRNAs and SARS-CoV-2 life cycle, pathogenesis, and mutations: biomarkers or therapeutic agents?MicroRNA와 SARS-CoV-2 수명 주기, 병인 및 돌연변이: 바이오마커 또는 치료제?Review Published on 2021-01-012022-09-11 Journal: Cell cycle (Georgetown, Tex.) [Category] MERS, SARS, 바이오마커, 변종, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral antiviral agent antiviral drug antiviral drugs applied binding Biomarker candidate cell proliferation complementary coronavirus coronavirus disease Coronavirus disease 2019 coronavirus vaccine COVID-19 COVID-19 therapy database databases determine differentiation drug Drug administration Efficacy Emergency use authorization food genomic genomic mutations Google Scholar involved life cycle metabolism microRNA miRNA miRNAs mRNA degradation mutations Pathogenesis pathological conditions pathophysiology patients patogenecity physiological protein synthesis respiratory RNAs SARS-CoV-2 SARS-CoV-2 life cycle searched severe acute respiratory syndrome Coronavirus shown single-stranded Stage target mRNA the SARS-CoV-2 the United State therapeutic therapy United States United States Food and Drug Administration untranslated region UTR Vaccine virus Web of Science [DOI] 10.1080/15384101.2020.1867792 PMC 바로가기 [Article Type] Review
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses Research Published on 2020-12-172022-10-05 Journal: Nature Medicine [Category] SARS, 유전자 메커니즘, 임상, [키워드] Activation acute respiratory syndrome animal Anti-spike antibody Antibody Response approach AZD1222 boost booster dose Booster vaccine cell activation cellular ChAdOx1 ChAdOx1 nCoV-19 clinical trials complement coronavirus coronavirus vaccine dose doses evaluated exploratory facilitate function functional antibody responses healthy homologous humoral immunogenicity data induce Infection Interim report magnitude multifunctional natural killer neutralizing antibody neutralizing antibody titers Open-label outcome phagocytosis phase Phase 3 Prevent preventing infection priming Randomized controlled trial receive reported Safe SARS-CoV-2 vaccine serology subgroup Support T cell response the vaccine Trial vaccination Vaccine viral spike protein Viral vector Volunteer [DOI] 10.1038/s41591-020-01179-4 [Article Type] Research
Deducing the N- and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2Article Published on 2020-12-092023-07-13 Journal: Glycobiology [Category] SARS, [키워드] coronavirus vaccine COVID-19 S1 S2 glycosylation SARS-CoV-2 glycosylation Spike protein [DOI] 10.1093/glycob/cwaa042 PMC 바로가기
Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidateResearch Paper Published on 2020-11-212023-06-14 Journal: EBioMedicine [Category] MERS, SARS, [키워드] coronavirus vaccine Intramuscular administration Live COVID-19 vaccine mouse-adapted SARS-CoV-2 Neutralizing antibodies Viral vector vaccine [DOI] 10.1016/j.ebiom.2020.103132 PMC 바로가기 [Article Type] Research Paper
Adjuvants for Coronavirus VaccinesImmunology Published on 2020-11-062022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] adjuvant adjuvants aluminum aluminum salt assist component coronavirus coronavirus disease Coronavirus disease 2019 coronavirus vaccine Coronavirus vaccines COVID-19 COVID-19 vaccines Critical Effect Efficacy and safety Evidence immune response Inactivated vaccine induce lack long-lasting MERS-CoV Middle East pandemic platform profile reported robust SARS-CoV SARS-CoV-2 subunit tested the SARS-CoV-2 TLR agonists Vaccine [DOI] 10.3389/fimmu.2020.589833 PMC 바로가기 [Article Type] Immunology
A review of COVID-19 vaccines in development: 6 months into the pandemic개발 중인 COVID-19 백신에 대한 검토: 전염병 발생 6개월Review Published on 2020-10-052022-08-31 Journal: The Pan African Medical Journal [Category] MERS, 비임상, 신약개발, 임상, [키워드] advent approach breath candidate clinical testing clinical trial clinical trials CLOCK conducted coronavirus coronavirus vaccine Coronavirus vaccines COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines develop DNA drugs expected expert humans inactivated market Medicine mRNA vaccines pandemic pre-clinical testing Spread subunit vaccines thematic analysis Vaccine vaccine candidate vaccine candidates Vaccine development virus [DOI] 10.11604/pamj.2020.37.124.24973 PMC 바로가기 [Article Type] Review
Induction of the Antiviral Immune Response and Its Circumvention by CoronavirusesReview Published on 2020-09-182022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory symptom antigen-presenting cells antiviral drugs antiviral immune response cascades catastrophic caused characterized circumvent coronavirus coronavirus vaccine Coronaviruses Cytokine storm early phase epidemic disease evade global pandemic highly pathogenic Host hosts Human immune immune evasion Impact induction Infection information innate immune Interaction interferon signaling intestinal tract knowledge lymphopenia Modification Novel coronavirus Pneumonia public health Replication response RNA SARS-CoV-2 shielding Surveillance viral tissue tropism virus zoonotic [DOI] 10.3390/v12091039 PMC 바로가기 [Article Type] Review
Mitigating Coronavirus Induced Dysfunctional Immunity for At-Risk Populations in COVID-19: Trained Immunity, BCG and “New Old Friends”Immunology Published on 2020-09-042022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Mycobacterium obuense animal anti-SARS-CoV-2 vaccine BCG Characteristics Combined contagious coronavirus SARS-CoV-2 coronavirus vaccine Coronaviruses COVID-19 cytokine dysfunctional immune response effective effort hallmark help high risk highly pathogenic IMM-101 immune cells immune response Immunity immunological immunopathological induced infectious agents knowledge Mycobacterium Novel coronavirus observation overcome pandemic patients with COVID-19 Population PROTECT representing Respiratory illness response risk Safe SARS severe COVID-19 disease Spread systemic level trained immunity Vaccine Vaccine development Vaccines [DOI] 10.3389/fimmu.2020.02059 PMC 바로가기 [Article Type] Immunology
Vaccination against SARS-CoV-2 and disease enhancement – knowns and unknownsOther Published on 2020-08-242022-10-31 Journal: Expert review of vaccines [Category] COVID-19, MERS, [키워드] accelerated Area clinical development coronavirus coronavirus vaccine Coronaviruses COVID-19 COVID-19 pandemic disease disease enhancement drastic effective Epidemic Evidence expert identify in vivo individual infectious disease outbreak Influenza knowledge measure MERS-CoV Protecting risk Safe SARS-CoV SARS-CoV-2 Spanish Spread tested theoretical risk vaccinated individual vaccination Vaccine vaccine candidate vaccine candidates vaccine safety while [DOI] 10.1080/14760584.2020.1800463 PMC 바로가기 [Article Type] Other