Micro-Fourier-transform infrared reflectance spectroscopy as tool for probing IgG glycosylation in COVID-19 patientsCOVID-19 환자에서 IgG 글리코 실화를 조사하기위한 도구로서 마이크로 푸리에 변환 적외선 반사 분광 광경.Article Published on 2022-03-112022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] Activation Adaptive immune response Anti-spike antibody Antibody Response Asymptomatic Biophotonics Blood Brazil carbonyl chemiluminescent immunoassay CLIA correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill Cutoff detection rate diagnosed with COVID-19 Diagnostic markers disease dissemination ELISA excessive inflammatory response extension glycosylation healthcare worker healthy helping IgA IgG IgG antibodies IgG1 IgM immune response Immunoglobulin indicated individual individuals with COVID-19 Infection marker Mild Optics and photonics Other photonics outcome Patient patients Physiology positive probe Quantitative RBD reported SARS-CoV-2 SARS-CoV-2 viral load serum sample serum samples severity signal specificity Viral Viral antigen Volunteer worsening [DOI] 10.1038/s41598-022-08156-6 PMC 바로가기 [Article Type] Article
Clinical findings, viral load, and outcomes of COVID-19: Comparison of patients with negative and positive initial chest computed tomographyCOVID-19의 임상 소견, 바이러스 부하 및 결과: 초기 흉부 컴퓨터 단층 촬영 음성 및 양성 환자의 비교Comparative Study Published on 2022-03-032022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] addition Admission age AUC characteristic Chest computed tomography Chest CT clinical Clinical characteristics Clinical data Clinical findings confidence interval COVID-19 CRP level Ct value Cutoff Diagnosis Efficacy evaluated examined Fever help Hospital stay initial intensive care intensive care unit admission male mean hospital stay negative and positive Odds ratio Older outcome Patient patients Pneumonia positive receiver operating characteristic report ROC significantly significantly higher tested the mean therapy threshold value Viral load viral loads [DOI] 10.1371/journal.pone.0264711 PMC 바로가기 [Article Type] Comparative Study
Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2Article Published on 2022-03-032022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] Antibody titer Antibody titers binding convalescent convalescent patient Cutoff detect diagnostic ELISA ELISAs evaluate exhibited FIVE Genscript individual IQR median Neutralizing antibodies neutralizing antibody plaque reduction neutralization population immunity pre-vaccination PRNT required SARS-CoV-2 Sensitivity and specificity serum samples sVNT vaccinated individuals vaccine trial Virology virus neutralization test [DOI] 10.1038/s41598-022-07597-3 PMC 바로가기 [Article Type] Article
Telehealth Management and Risk Stratification of Older Patients With Chronic Heart Failure During COVID-19 Pandemic: Prognostic Evaluation of the TeleHFCovid19-ScoreObservational Study Published on 2022-03-012022-10-05 Journal: Journal of the American Medical Directors Associat [Category] SARS, 임상, [키워드] 95% CI activities Administered age Analysis baseline Care characteristic chronic composed coronavirus disease COVID-19 Cutoff death diuretics Dyspnea edema effort evaluate failure groups heart heart failure High-dose Hospitalization identify less loop diuretics management Older older patient outcome Outpatient pandemic Patient Prospective Study questionnaire reported risk risk stratification SARS-CoV-2 setting significantly lower specificity subjects telehealth Telemedicine was obtained weighed women worsening [DOI] 10.1016/j.jamda.2021.12.024 PMC 바로가기 [Article Type] Observational Study
Humoral serological response to the BNT162b2 vaccine is abrogated in lymphoma patients within the first 12 months following treatment with anti-CD2O antibodiesBNT162b2 백신에 대한 체액 혈청학적 반응은 항-CD2O 항체 치료 후 첫 12개월 이내에 림프종 환자에서 폐지됩니다.Article Published on 2022-03-012022-09-12 Journal: Haematologica [Category] MERS, SARS, 진단, [키워드] Abbott abrogated administration Analysis anti-CD20 antibody blood sample BNT162b2 vaccine CD20 COVID-19 cross-sectional Cutoff develop dose enrolled Factor generate humoral identify IgG Immunity injection lymphoma monoclonal antibodies monoclonal antibody morbidity and mortality of BNT162b2 Patient patients Pfizer positive response predictors second dose serological response the SARS-CoV-2 therapy treated Treatment vaccination schedule Vaccine vaccine dose were measured while [DOI] 10.3324/haematol.2021.279216 PMC 바로가기 [Article Type] Article
Neutralizing Antibodies and Cytokines in Breast Milk After Coronavirus Disease 2019 (COVID-19) mRNA VaccinationContents Published on 2022-02-282022-10-28 Journal: Obstetrics and gynecology [Category] COVID-19, COVID19(2023년), SARS, [키워드] acute respiratory syndrome Anti-RBD antibody anti-RBD IgA Anti-RBD IgG antibody B.1.1.7 B.1.351 Beta Blood Breast breast milk Breastfeeding Cellular immune response cohort study collected controls coronavirus coronavirus disease correlated COVID-19 COVID-19 vaccination Cutoff cytokine D614G domain Dried blood spots driven by enrolled enzyme-linked immunosorbent evaluate expressed first dose Gamma IgG immune response Immunoglobulin Infant Infants interferon-γ lactating women Level milk mother mRNA mRNA-based mRNA-based COVID-19 vaccine mRNA-based vaccine neutralize neutralized neutralizing antibody P.1 passive immunity positive provided RBD reflected SARS-CoV-2 second dose second vaccination Side effects Stool Stool sample tested transfer transferred vaccination Vaccine variant variants of concern were measured were used women [DOI] 10.1097/AOG.0000000000004661 PMC 바로가기 [Article Type] Contents
T Cell Response After SARS-CoV-2 Vaccination in Immunocompromised Patients with Inflammatory Bowel Disease염증성 장 질환이 있는 면역 저하 환자에서 SARS-CoV-2 백신 접종 후 T 세포 반응Article Published on 2022-02-232022-09-11 Journal: Journal of Crohn's & colitis [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence age analysed anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody titres blood sample Blood samples Cell cellular cellular and humoral immune response Cellular immune response cellular immunity close monitoring comparable Control controls COVID19 Cutoff detect dose of vaccination Efficacy first dose group healthy healthy control healthy controls humoral immune response IBD IFN-γ immune response immune responses Immunity Immunocompromised Immunosuppression immunosuppressive infection with SARS-CoV-2 Inflammatory bowel disease one patient Patient patients PROTECT recruited regimens response SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 vaccination second dose slight increase T cell T cell response Th cells TNF TNF-α Total university vaccination [DOI] 10.1093/ecco-jcc/jjab147 PMC 바로가기 [Article Type] Article
Global Longitudinal Strain to Predict Respiratory Failure and Death in Patients Admitted for COVID-19-Related DiseaseArticle Published on 2022-02-152022-11-16 Journal: The American journal of cardiology [Category] 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory distress Admission cardiovascular system center Complete consecutive patient continuous variable COVID Cutoff death decrease detect early treatment enrolled evidence of failure fraction hazard ratio help high-risk patient higher risk Hospitalization intubation longitudinal mechanical ventilation Mortality outcome oxygen P/F Patient patients patients with COVID-19 remained respiratory Respiratory function Risk factors risk stratification secondary outcome severe disease significantly strain syndrome ventricular was performed worsening [DOI] 10.1016/j.amjcard.2021.10.046 PMC 바로가기
Evaluation of the Potential Risk of Mortality from SARS-CoV-2 Infection in Hospitalized Patients According to the Charlson Comorbidity IndexArticle Published on 2022-02-122022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] calculated calculator carried CCI Charlson Comorbidity Index Charlson index clinical collected Comorbidity COVID-19 COVID-19 complication Cutoff death died evaluate evaluated global public health hospitalized patient identify increased the risk intubation measure Mortality obesity Odds ratio pandemic of COVID-19 Patient patients hospitalized patients who survived positive Potential predictor presence of comorbidity reflected ROC Curve SARS-CoV-2 SARS-COV-2 infection sensitivity specificity study population the patient with COVID-19 [DOI] 10.3390/healthcare10020362 PMC 바로가기 [Article Type] Article
Role of a lower cutoff of high sensitivity troponin I in identification of early cardiac damage in non-severe patients with COVID-19중증이 아닌 COVID-19 환자에서 조기 심장 손상을 식별하는 데 있어 고감도 트로포닌 I의 더 낮은 컷오프의 역할Article Published on 2022-02-112022-09-10 Journal: Scientific Reports [Category] MERS, 바이오마커, 임상, 치료기술, [키워드] bilateral pneumonia Biomarkers cardiac cardiac damage Cardiology cardiovascular clinical coronavirus disease Coronavirus disease 2019 COVID-19 CRP Cutoff detectable Diseases four groups hospital Hospital admission incidence IQR lymphocyte Lymphocyte count manifestation Manifestations non-severe patient non-severe patients Pathogenesis Patient patients patients with COVID-19 Pneumonia proportion radiological role sensitivity significantly higher symptoms onset three group troponin I with COVID-19 [DOI] 10.1038/s41598-022-06378-2 PMC 바로가기 [Article Type] Article