Do Elevated Levels of Inflammatory Biomarkers Predict the Risk of Occurrence of Ischemic Stroke in SARS-CoV2 ?: An Observational Study염증성 바이오마커 수치 상승이 SARS-CoV2에서 허혈성 뇌졸중 발생 위험을 예측합니까?: 관찰 연구Observational Study Published on 2021-11-012022-09-11 Journal: Journal of stroke and cerebrovascular diseases : t [Category] 바이오마커, 임상, [키워드] absence age Analysis association binary Characteristics clinical Clinical characteristics collected Control Conventional COVID Covid stroke COVID-19 cut-off CVD D-dimer diabetes Diabetes Mellitus dimer elevated ESR Gender greater hypertension IBM identify independent Inflammatory biomarker inflammatory biomarkers Ischemic Ischemic Stroke Laboratory parameters Level material Multivariate analysis multivariate logistic regression Occurrence outcome Patient patients positive positive patient Predictive Predictive value predictor reported Risk factors RT- PCR SARS-CoV2 SARS-CoV2 infection severity stroke stroke risk the strongest was used [DOI] 10.1016/j.jstrokecerebrovasdis.2021.106063 PMC 바로가기 [Article Type] Observational Study
Targeting Macrophage Dysregulation for Viral Infections: Novel Targets for ImmunomodulatorsImmunology Published on 2021-11-012022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] activated Activation Antiretroviral therapy ART cardiovascular disease CD4+ cell death cells Central nervous system Chikungunya CNS co-morbidity Comorbidities Comorbidity CVD Disease progression driving dysregulation event HIV-1 Human immunodeficiency virus immune dysregulation immunomodulators immunomodulatory Infection Inflammation Influenza initial Macrophage myeloid cell myeloid cells Neurological deficit novel Pathogenesis persist persistence PLWH resulting SARS-CoV-2 survival systemically target targeting tissue undergo viral infection viral infections viral replication kinetics Viral reservoir viruses [DOI] 10.3389/fimmu.2021.768695 PMC 바로가기 [Article Type] Immunology
COVID-19: The Cause of the Manifested Cardiovascular Complications During the PandemicCardiovascular Medicine Published on 2021-10-282022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] affected affecting blind cardiac cardiovascular cardiovascular complication cause clinical recovery Cohort Complication Course COVID-19 CVD decrease disease driven by Effect health care systems healthy heart immunization Impact impacted individuals Infection Inflammation Manifestations Measures morbidities myocardial damage National pandemic Pandemics pediatric question reported SARS-CoV-2 significantly Spread stability subsequent Surveillance the disease virus [DOI] 10.3389/fcvm.2021.744482 PMC 바로가기 [Article Type] Cardiovascular Medicine
Serum Neurofilament Light is elevated in COVID-19 Positive Adults in the ICU and is associated with Co-Morbid Cardiovascular Disease, Neurological Complications, and Acuity of IllnessArticle Published on 2021-10-202022-11-01 Journal: Cardiology and cardiovascular medicine [Category] COVID-19, [키워드] Acuity Alzheimer’s disease blood chemistry cardiovascular cardiovascular disease Co-Morbid Cardiovascular Disease cognitive consequence correlated COVID-19 COVID-19 patients COVID-19 positive patient Critically ill CVD Dementia demographics diabete diabetes disease dysfunction elevated examined healthy control ICU ICU patient illness increase in Inflammation Injury intensive care Level LIGHT log measure nervous system neurofilament neurological Neurological complication Neurological complications neuronal Organ failure Patient positive Prevent Primary outcome Protein risk SARS-CoV-2 serum Serum Neurofilament severe COVID-19 disease significantly higher SOFA SOFA score subject survivor systemic inflammatory systemic inflammatory disease t-test therapy understanding while [DOI] 10.26502/fccm.92920221 PMC 바로가기 [Article Type] Article
Acute Myocardial Injury and Rhabdomyolysis in COVID-19 Patients: Incidence and MortalityCardiology Published on 2021-10-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] ACE2 Angiotensin converting enzyme 2 (ACE2) angiotensin-converting enzyme 2 benefit binding Cardiomyopathy cardiovascular disease caused cohort study coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 patient COVID-19 patients creatine kinase (ck) Critical CVD defined elevated enzyme female fiber fibrosis Frequency greater higher risk Hospitalized hospitalized COVID-19 patient hospitalized patients Host hyperinflammatory cytokine storm hypoxic immune in-hospital mortality incidence indirect mechanism Injury ischemic injury male material Mortality mortality rate muscle myocardial injury myocardial ischemia type 2(mi type 2) myocarditis Necrosis Odds ratio outcome pathophysiology Patient patients with COVID-19 Primary outcome Result retrospective rhabdomyolysis SARS-CoV-2 virus serum Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) significantly higher Skeletal muscle Stress systemic cytokine Troponin-T [DOI] 10.7759/cureus.18899 PMC 바로가기 [Article Type] Cardiology
Excess deaths from all causes and by COVID-19 in Brazil in 2020Original Article Published on 2021-10-182022-10-29 Journal: Revista de Saúde Pública [Category] COVID-19, MERS, SARS, [키워드] age Brazil cardiovascular disease cause cause of death causes COVID-19 CVD death deaths Evidence excess expected FIVE groups heterogeneous Impact in some increase in individual individuals measure men Mortality mortality rate neoplasm Neoplasms, mortality occurred Older opposite Racial reduction reduction in mortality reductions in Respiratory disease respiratory diseases risk of death selected Sex System were used women [DOI] 10.11606/s1518-8787.2021055004137 PMC 바로가기 [Article Type] Original Article
Preventing the Next Pandemic: The Case for Investing in Circulatory Health – A Global Coalition for Circulatory Health Position PaperInvited Editorial Published on 2021-10-122022-10-31 Journal: Global Heart [Category] COVID-19, MERS, SARS, [키워드] addition addressed approach build cardiovascular disease Care Chronic kidney disease Circulatory Circulatory Health co-morbidity Coalition Community Consequences COVID-19 COVID-19 pandemic COVID-19 patients CVD death determinant diabetes disease Emergency emotional equity explicit form framework globe greater Health Health Emergency Preparedness health systems healthcare Healthcare system hypertension indicate Investing Kidney disease member Mental NCD noncommunicable disease obesity Older age pandemic paper patients physical Policy position prevalent Preventing provide public health resulting risk robust state stroke Support sustainable development goal syndemic thrombotic complication Vaccine WHO [DOI] 10.5334/gh.1077 PMC 바로가기 [Article Type] Invited Editorial
The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients돼지에서 대사 증후군의 심장 분자 설정은 질병 감수성을 나타내며 환자에서 Covid-19 결과를 악화시키는 메커니즘을 제안합니다.Article Published on 2021-10-052022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] aggregation Analysis animal model Arterial thrombosis association Blood blood test blood tests capture cardiovascular disease cardiovascular diseases change Comorbidity Complement pathway component components computational analysis COVID-19 CVD deregulation develop diabete diabetes disease elevated enriched pathway enzyme exacerbate expressed greater hallmark hallmarks hypertension identity immune response investigated mechanism metabolic syndrome metabolite metabolites metabolomics molecular Myocardial Myocardium obese obesity outcome overexpressed pathophysiology Patient patients patients with COVID-19 PIGS Platelet platelet aggregation pro-inflammatory pro-inflammatory markers Protein proteomics reveal risk risk factor Risk factors RNA methylation susceptibility syndrome Therapeutic approach thrombosis transcriptomics virus viruses while [DOI] 10.1038/s41598-021-99143-w PMC 바로가기 [Article Type] Article
Association of pre-existing comorbidities with mortality and disease severity among 167,500 individuals with COVID-19 in Canada: A population-based cohort study캐나다에서 COVID-19를 가진 167,500 명의 사망률 및 질병 심각성과 기존 동반 합병증의 협회 : 인구 기반 코호트 연구Research Article Published on 2021-10-052022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] 30-Day mortality 95%CI addition adjust age Arthritis association Asthma Canada Cancer cardiovascular disease Chronic kidney disease chronic obstructive chronic obstructive pulmonary disease chronic obstructive pulmonary disease (COPD) Cohort studies collected Comorbidities Comorbidity conducted COPD coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis Cox proportional hazard CVD database death Dementia diabete diabetes diagnosed disease severity elevated Evidence examined FIVE follow-up period General population group groups Health higher risk highlight HIV Hospitalization Hospitalized hypertension include individual individuals individuals with COVID-19 Kidney disease limitation logistic regression model logistic regression models median mental illness Mortality multiple comorbidities Novel coronavirus novel coronavirus disease number of comorbidity obstructive pulmonary disease Older age outcome outcomes population-based cohort predictor predominant previous study Primary outcome pulmonary disease Racial Regression model Result retrospective cohort study rheumatoid arthritis risk risk factor Risk factors secondary outcome severity Significant solid organ solid organ transplant stratified vaccination variable variables variants of concern world population [DOI] 10.1371/journal.pone.0258154 PMC 바로가기 [Article Type] Research Article
Neurological complications of COVID-19 in hospitalized patients: The registry of a neurology department in the first wave of the pandemicObservational Study Published on 2021-10-012022-10-05 Journal: European journal of neurology [Category] SARS, 임상, [키워드] acute respiratory syndrome Cerebrovascular disease Cohort complications complications of COVID-19 conducted coronavirus COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 patient COVID-19 symptoms CVD diagnose disorder disorders early phase Encephalopathy Evidence First wave groups hospital Hospitalized hospitalized patient Invasion involved mechanism Mortality nervous system neurological Neurological complication Neurological complications occurred pandemic Patient patients hospitalized polymerase chain Prevalence Prospective Study required SARS-CoV-2 Seizure Spain suffered syndrome [DOI] 10.1111/ene.14748 PMC 바로가기 [Article Type] Observational Study