The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa고도로 다형적인 CYP6M7 사이토크롬 P450 유전자는 방향적으로 선택된 CYP6P9a 및 CYP6P9b 유전자와 함께 아프리카 말라리아 매개체인 Anopheles funestus에서 피레스로이드 저항성의 전선을 확장합니다.Research Article Published on 2014-09-272024-08-13 Journal: BMC Genomics [Category] 말라리아, [키워드] Anopheles funestus CYP6M7 cytochrome P450 directional selection Insecticide resistance malaria Pyrethroids [DOI] 10.1186/1471-2164-15-817 PMC 바로가기 [Article Type] Research Article
DDT and pyrethroid resistance in Anopheles arabiensis from South Africa남아프리카의 Anopheles arabiensis에서 DDT 및 피레스로이드 저항성Research Published on 2013-08-082024-08-13 Journal: Parasites & Vectors [Category] 말라리아, [키워드] cytochrome P450 Deltamethrin glutathione S-transferase Insecticide resistance Microarrays Permethrin South Africa [DOI] 10.1186/1756-3305-6-229 PMC 바로가기 [Article Type] Research
Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study흡입 코르티코스테로이드 처방을 받은 환자들의 대상 연구에서 대상포진 발병 위험.Research Article Published on 2011-12-162023-05-22 Journal: BMC Pulmonary Medicine [Category] Fulltext, 대상포진, 두창, 수두, 홍역, [키워드] adverse drug effects cytochrome P450 herpes zoster inhaled corticosteroids observational studies [DOI] 10.1186/1471-2466-11-59 PMC 바로가기 [Article Type] Research Article
Genetic Variation of the Human α-2-Heremans-Schmid Glycoprotein (AHSG) Gene Associated with the Risk of SARS-CoV InfectionResearch Article Published on 2011-08-172022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] 95% CI 95% confidence interval adjusted odds ratio affected After age and sex AHSG Analysis AOR association Beijing Cohort cohort study Concentration CYP4F3 cytochrome P450 demonstrated family found Gene Genotype genotype data genotyped Guangzhou HCW healthy control Human human neutrophil inflammation-associated gene Inflammatory investigated leukotriene Linkage disequilibrium liver LTB4 Macrophage nucleocapsid protein polymorphism promoter Protein regulated Regulation required SARS Coronavirus SARS virus SARS-CoV SARS-CoV infection selected serum Serum level significantly SNP statistical analysis supported susceptibility the patient transcriptional activity variant [DOI] 10.1371/journal.pone.0023730 PMC 바로가기 [Article Type] Research Article
Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids현장에서 포착된 퍼메트린 내성 Anopheles gambiae CYP6P3, 피레스로이드를 대사하는 P450 과발현Research Article Published on 2008-11-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] A. gambiae adaptive adaptive mechanism adaptive mechanisms Alpha alpha-cyano Anopheles gambiae anopheline mosquitoes Author bioassays compounds Critical CYP6P3 cytochrome P450 detect disease spread Efficacy ENCODE enzyme Enzymes Evolution facilitate found Frequency Gene Gene Expression Genetic Health health problem identify individual insect insecticide insecticides Insects involved lead low frequencies malaria malaria vector malaria vector control mechanism Messenger RNA Metabolic resistance metabolise Molecular assay molecular mechanism molecular mechanisms MONITOR natural selection overexpressed P450 pesticide pesticides phenotyped populations public health pyrethroid Pyrethroids receiving recessive allele reducing resistance significantly sub-Saharan Africa Survivors sustainability trait transcript level translated Transmission undergo [DOI] 10.1371/journal.pgen.1000286 PMC 바로가기 [Article Type] Research Article