PrimedSherlock: a tool for rapid design of highly specific CRISPR-Cas12 crRNAs
Article
[키워드] assays
automated
benefit
bioinformatics
Cas12 nuclease assay
Cas12a
Combination
conserved
CRISPR
CRISPR-Ca
CRISPR-Cas12
Critical
demonstrated
Dengue
diagnostic
diagnostics
Efficiency
facilitated
FDA approval
field
Field forward diagnostics
flavivirus
genomes
genomic
HIV
In-vitro
Intensive
isothermal
isothermal amplification
manual curation
Nile
nucleases
nucleic acid
offer
parameter
Pathogens
platform
polymorphism
PrimedRPA
PrimedSherlock
primer
primer pair
Primers
qRT-PCR
regions
RNA
robust
SARS-CoV-2
Serological assay
serotype
SHERLOCK
significantly
specificity
strain
Strains
target
targets
Vector-borne disease
West
West Nile
wildtype
Zika
Zika.
[DOI] 10.1186/s12859-022-04968-5 PMC 바로가기
[DOI] 10.1186/s12859-022-04968-5 PMC 바로가기