Using the Newcomb–Benford law to study the association between a country’s COVID-19 reporting accuracy and its developmentArticle Published on 2021-11-252022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, SARS, [키워드] Accuracy association country Coverage COVID-19 COVID-19 pandemic cumulative death developmental deviate Epidemiology expenditures healthcare highlight independent indicate Infectious diseases less measure OLS regression Pandemics provide reported robust Statistical methods surveillance data treated [DOI] 10.1038/s41598-021-02367-z PMC 바로가기 [Article Type] Article
“Watch Me Grow- Electronic (WMG-E)” surveillance approach to identify and address child development, parental mental health, and psychosocial needs: study protocol“아동 발달, 부모의 정신 건강 및 심리 사회적 요구를 식별하고 해결하기위한“성장하는 전자식 (WMG-E)”감시 접근법 : 연구 프로토콜Study Protocol Published on 2021-11-172022-09-10 Journal: BMC health services research [Category] MERS, SARS, 비임상, 임상, [키워드] acceptability approach assessment breath Care Child development children closure CONSORT CONSORT statement continuity Continuity of care Controlled COVID-19 pandemic developmental Developmental surveillance Digital solution effective Electronic platform engage expand expected Families feasibility Health health organisation health organisations Health promotion health promotion program identify impacted implementation implication increased risk intervention group management mental health MONITOR Online health service pandemic parent Parent mental health parental parents platform Population Psychosocial needs Psychosocial stress Randomly RCT receive recommendation recommendations recruited Registered registration number resource resulting risk Screening Service navigation Study protocol Support Surveillance Trial Trial registration Version Virtual care [DOI] 10.1186/s12913-021-07243-0 PMC 바로가기 [Article Type] Study Protocol
Randomized Controlled Study to Test the Effectiveness of Developmental Network Coaching in the Career Advancement of Diverse Early-Stage Investigators (ESIs): Implementation Challenges and Lessons LearnedRandomized Controlled Trial Published on 2021-11-162022-10-04 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 임상, [키워드] added Adding advancement affected African Americans Algorithms Analysis Asian assistant Associate Blinding career career development challenge Characteristics Coaching Cohort Controlled COVID-19 COVID-19 pandemic demographics developmental developmental networks distribution Diversity early-stage investigators ENhance ESI foundation grant writing group implementation Intervention Latinx lesson mechanism mentorship mock study section National Research Mentoring Network (NRMN) nested cluster randomization network NIH outcomes pandemic participant predictor Professor randomization recruit recruited Research Resolution Sample size Science Section Sex significantly Study design Support Test [DOI] 10.3390/ijerph182212003 PMC 바로가기 [Article Type] Randomized Controlled Trial
Machine learning and network medicine approaches for drug repositioning for COVID-19Article Published on 2021-11-092022-10-04 Journal: Patterns [Category] 신약개발, 치료제, [키워드] Abstract Algorithm antiviral drugs approach broad-spectrum antiviral broad-spectrum antivirals cellular processe Clinical use compassionate use complementary connectivity COVID-19 developmental drug Drug repurposing Effectiveness experiment explorer Factors FDA-approved drug graph graph visualization Host host protein hypothese Hypothesis IMPROVE include indicated induce information kernels on graphs machine machine learning approach Map methodology network medicine non-negative matrix factorization online tool Perturbation pharmacological predict predicted Protein reduced SARS- CoV-2 SARS-CoV-2 significantly transcriptomics Treatment viral disease while [DOI] 10.1016/j.patter.2021.100396 PMC 바로가기 [Article Type] Article
SARS-CoV-2 vaccine testing and trials in the pediatric population: biologic, ethical, research, and implementation challenges소아 집단에 대한 SARS-CoV-2 백신 테스트 및 시험: 생물학적, 윤리적, 연구 및 구현 과제Article Published on 2021-11-012022-09-11 Journal: Pediatric Research [Category] SARS, 임상, [키워드] accelerate adaptive addressed Adolescence Adults Affect affected allocation approach biologic Care changes in childhood children chronic conditions chronic disease clinical trial clinical trials Community conditions COVID-19 COVID-19 disease COVID-19 pandemic developmental developmental disorder developmental disorders Diseases Effect effective Effectiveness enrolled equity ethical concerns Health health inequities health system immune immune system Immunity implementation include innate and adaptive immunity knowledge majority maturation nation other disease other diseases pediatric populations rationale required Research risk SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines symptomatic threshold Trial unique vaccination Vaccinations Vaccine Vaccine hesitancy variety weighed [DOI] 10.1038/s41390-021-01402-z PMC 바로가기 [Article Type] Article
An mCARE study on patterns of risk and resilience for children with ASD in BangladeshArticle Published on 2021-11-012022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] aggression ASD assessment average Behavior Care cascade Cell children control group COVID-19 daily living detrimental developmental disorder evaluate future risk Health Human behaviour inactive lockdown mitigate outcome parameter platform problems Resilience risk Risk factors sensitivities Support was collected were assessed [DOI] 10.1038/s41598-021-00793-7 PMC 바로가기 [Article Type] Article
Mental Health and Substance Use Associated with Hospitalization among People with COVID-19: A Population-Based Cohort StudyCovid-19를 가진 사람들의 입원과 관련된 정신 건강 및 약물 사용 : 인구 기반 코호트 연구Article Published on 2021-10-312022-09-01 Journal: Viruses [Category] MERS, 진단, [키워드] 95% CI adjusted age alcohol Analysis aRR Asthma Cancer chronic condition chronic conditions Chronic kidney disease Cohort studies Comorbidities COVID-19 COVID-19 case deaths developmental developmental disabilities developmental disability diabete diabetes Diabetes Mellitus disorder disorders drugs emergency room evaluated Factor group Hospital admission Hospitalization hospitalizations Hospitalized hypertension Immunosuppression increased risk increasing age injection insulin intellectual disability Kidney disease Male sex mental health multivariable Older age Poisson regression Pregnancy registries reproductive risk Risk factors risk ratio robust error variance Schizophrenia substance Substance use substance-related disorders treated used data women [DOI] 10.3390/v13112196 PMC 바로가기 [Article Type] Article
Data Linkage in Australia: The First 50 YearsReview Published on 2021-10-282022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] Anomaly Australia Australian Community complex contributed COVID-19 pandemic cross-jurisdiction data linkage developmental Health Impact linkage National overcome provide Support Year [DOI] 10.3390/ijerph182111339 PMC 바로가기 [Article Type] Review
K 2P 18.1 translates T cell receptor signals into thymic regulatory T cell developmentArticle Published on 2021-10-262022-10-04 Journal: Cell Research [Category] 신약개발, [키워드] Activation Autoimmune Autoimmunity Calcium signalling cell fate Clinical outcome developmental disorders dominant-negative driving expression facilitated gain-of-function identify in vitro in vivo increase in intracellular calcium Ion channel signalling Loss lymphoproliferative mice Mild Missense modulated modulation multiple sclerosis Mutation NF-κB Patient phenotype potassium channel provided reduced Regulatory Regulatory T cell selection process sustained T cell T cell receptor TCR therapeutic thymic thymic emigrant thymocyte transcription factor translate Treg upregulation urinary tract infections variant [DOI] 10.1038/s41422-021-00580-z PMC 바로가기 [Article Type] Article
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19Article Published on 2021-10-232022-10-30 Journal: iScience [Category] COVID-19, [키워드] Abstract Atypical autoantibody Autoimmunity B cell B cell response B cells BCR blunting CD11c CD80 cellular COVID-19 developmental disease severity identify IGHV4-34 IL-4 immunology immunopathology Intervention memory Neutralizing antibodies pathological response Patient plasmablast polyclonal Population provoke reaction response selected serological single-cell suppress Trajectories trajectory transcriptional transcriptomic transcriptomics viral infections Virology [DOI] 10.1016/j.isci.2021.103325 PMC 바로가기 [Article Type] Article