direct infection – Page 5 – Communicable Diseases Research

SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function

Article

Published on 2021-02-132022-10-29
Journal: Stem Cell Reports [Category] COVID-19, MERS, SARS,

The cytokine storm and thyroid hormone changes in COVID-19

코로나19의 사이토카인 폭풍과 갑상선 호르몬 변화

Review

Published on 2021-02-092022-09-10
Journal: Journal of Endocrinological Investigation [Category] MERS, 치료제,

Case Report: Myopathy in Critically Ill COVID-19 Patients: A Consequence of Hyperinflammation?

Neurology

Published on 2021-01-292022-11-01
Journal: Frontiers in Neurology [Category] COVID-19,

[키워드] ACE2 receptor Admission Affect amplitude Autoimmune C-reactive protein changes in clinical Complication compound muscle action potential duration consequence continuum COVID-19 Critical critical illness myopathy cytokine release described direct infection distal drugs elevated homeostatic hyperinflammation Ill Inflammatory cytokines intensive care treatment Interaction interleukin 6 Laboratory latency limbs median membrane metabolic pathway Motor nerve muscle muscular myalgia myopathic Myopathy Necrosis needle Pathogenesis pathophysiological Patient patients Pneumonia proximal proximal muscle reflect SARS-CoV-2 serum slow muscle fiber survived systemic inflammatory response the patient virus weakness
[DOI] 10.3389/fneur.2021.625144 PMC 바로가기 [Article Type] Neurology

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

K18-hACE2 마우스에서 SARS-CoV-2의 비강내 접종 후 신경 침범 및 뇌염

Article

Published on 2021-01-192022-09-10
Journal: Viruses [Category] 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Brain brains Cell cell death Central nervous system characterized chemokines CNS Coronavirus-2 correlated COVID-19 cytokine Cytokines declined direct infection Encephalitis exhibited hACE2 hallmark hemorrhage highest humans infect cell Infection Infectious virus Inflammatory response inoculation intranasal K18-hACE2 K18-hACE2 mice leukocyte leukocyte infiltration lung Lungs mice Mortality nasal nasal turbinate Neuroinflammation neuroinvasion Neurological disease neuronal olfactory olfactory bulb Onset Pathogenesis pathogenesis of SARS-CoV-2 plaque-forming unit plaque-forming units respiratory SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 neuroinvasion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe disease Viral virus titer virus titers
[DOI] 10.3390/v13010132 PMC 바로가기 [Article Type] Article

Granulomatous interstitial nephritis in a patient with SARS-CoV-2 infection

SARS-CoV-2 감염 환자의 육아종성 간질성 신염

Case Reports

Published on 2021-01-082022-09-01
Journal: BMC Nephrology [Category] 진단,

[키워드] acute kidney failure Acute kidney injury acute respiratory distress acute respiratory distress syndrome adjust Admission AKI Autopsy Case report case reports causes Clinical diagnosis clinical disease Collapsing coronavirus coronavirus disease Corticosteroid Corticosteroids COVID-19 Critically ill critically ill patients decision dialysis differential diagnose direct infection discharged Evidence evidence of glomerulopathy Granulomatous interstitial nephritis hemodynamic instability Hemolysis Infection Injury intensive care intensive care unit Interstitial nephritis kidney Kidney diseases Kidney failure Kidney function Kidney injury maculopapular rash management medication medications morbidity morbidity and mortality Most patients multi-organ failure Necrosis Other outcome over pathology Patient patient with COVID-19 patient with SARS-CoV-2 patients with COVID-19 peripheral smear positive presentation Rash rehabilitation facility required respiratory distress SARS-CoV-2 Sepsis severe acute respiratory distress syndrome severe coronavirus disease severe COVID-19 subsequent syndrome the patient therapy thrombotic thrombotic microangiopathy transfusion treatable was performed
[DOI] 10.1186/s12882-020-02213-w PMC 바로가기 [Article Type] Case Reports

Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain

31

Published on 2021-01-072022-10-28
Journal: Pain Reports [Category] COVID-19,

The COVID-Kidney Controversy: Can SARS-CoV-2 Cause Direct Renal Infection?

COVID-신장 논쟁: SARS-CoV-2가 직접 신장 감염을 일으킬 수 있습니까?

Review

Published on 2021-01-012022-09-12
Journal: Nephron [Category] MERS, 진단,

Deposition distribution of the new coronavirus (SARS-CoV-2) in the human airways upon exposure to cough-generated droplets and aerosol particles

Article

Published on 2020-12-312022-10-29
Journal: Scientific Reports [Category] COVID-19, MERS, SARS,

[키워드] ACE2 acute respiratory syndrome addition airway airways angiotensin-converting enzyme 2 applied binding bystander Cell cellular entry Clinical deterioration coronavirus cough coughs COVID-19 deposition direct infection disease distribution droplet effort expressed Fluid dynamics form human airway infect infected patient infected with SARS-CoV-2 Infection initial symptom less majority Mild Model nasal New coronavirus non-specific oral mucosa pandemic parameter Particle Particles pathogen Pathogenesis Pneumonia Probability produced progression quarantine receptor reducing Respiration respiratory droplet SARS-CoV-2 SARS-COV-2 infection significantly sneezes Spread stochastic Symptom target target cells the disease thought tissue Transport Treatment upper airway upper airways upper respiratory tract viral infection Viral load virus while
[DOI] 10.1038/s41598-020-79985-6 PMC 바로가기 [Article Type] Article

Endothelium Infection and Dysregulation by SARS-CoV-2: Evidence and Caveats in COVID-19

SARS-CoV-2에 의한 내피 감염 및 조절 장애: COVID-19의 증거 및 주의 사항

Review

Published on 2020-12-262022-09-10
Journal: Viruses [Category] MERS, SARS, 치료제,

[키워드] ACE2 acute respiratory syndrome ADAM17 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 binding bradykinin–kallikrein pathway caused cellular receptor clinical development Complication contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Deleterious direct infection downregulation dysfunction Endothelial cell endothelial cells Endothelial dysfunction Endothelium event Evidence evidence of exacerbate global public health human lung immunothrombosis include infect Inflammatory lead manifestation Neurological diseases pandemic parameter pericyte Protein RAAS recent renal respiratory Respiratory illness SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 replication severe COVID-19 severe disease spike Spike protein therapeutic agent therapeutic agents Therapeutics thrombotic Viral viral spike protein
[DOI] 10.3390/v13010029 PMC 바로가기 [Article Type] Review

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes

SARS-CoV-2는 인간 심근세포를 감염시키고 세포독성 효과를 유도합니다

Article

Published on 2020-12-012022-09-11
Journal: Cardiovascular Research [Category] MERS, SARS, 진단, 치료기술, 치료법, 치료제,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antiviral drug Apoptosis blocked Caco-2 cardiac injury cardiomyocyte Cardiosphere Cardiotoxicity cathepsin cathepsin-dependent Cathepsins caused cell lines Concentration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytotoxic effect demonstrated dependent on direct infection double-stranded Effect elevated enzyme expression global pandemic glycoprotein heart Heart slice higher risk in vitro Increasing induce infect Infection infection with SARS-CoV-2 infections Inflammation inhibited Injury interferon lead Lung injury marker Mortality oxygen Particle pathway Pathways Patient reactive oxygen Remdesivir respiratory RNA sequencing SARS-CoV-2 SARS-COV-2 infection secondary to severe acute respiratory syndrome Coronavirus spike glycoprotein Spike protein strain Stress supernatant supernatants tissue transcriptional response up-regulation Viral viral infection viral particle Viral particles Viral RNA viral spike viral spike protein
[DOI] 10.1093/cvr/cvaa267 PMC 바로가기 [Article Type] Article