Aktueller Stand der Impfung gegen SARS-CoV-2Hot Topics Published on 2021-02-022022-10-28 Journal: Zeitschrift Fur Rheumatologie [Category] COVID-19, MERS, SARS, [키워드] BNT162b2 Cambridge COVID-19 EMA Impfung Mainz Moderna mRNA vaccination mRNA Vakzine New York City Pfizer SARS-CoV-2 SARS-CoV‑2 Stand STIKO Empfehlung STIKO recommandation union USA vaccination [DOI] 10.1007/s00393-021-00966-9 PMC 바로가기 [Article Type] Hot Topics
Challenges and Adaptation of a European Influenza Vaccine Effectiveness Study Platform in Response to the COVID-19 Emergence: Experience from the DRIVE ProjectArticle Published on 2021-01-252022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, [키워드] adaptation affected Analysis build challenge circulation component COVID-19 COVID-19 pandemic COVID-19 vaccine development Effectiveness element EMA Europe European European Medicines Agency expected experience feasibility Guidance impacted Influenza influenza vaccine initiated initiative joint limit lockdown policy Medicine overlapped pandemic platform public health reached response Social distancing measure subsequent test-negative design vaccination Vaccine vaccine effectiveness [DOI] 10.3390/ijerph18031058 PMC 바로가기 [Article Type] Article
Cluster analysis of insomnia symptoms during COVID-19 pandemic: a general population web-based survey in IranOriginal Article Published on 2021-01-012022-10-28 Journal: Sleep Science [Category] COVID-19, [키워드] Administered age Analysis association cluster analysis conducted Coronavirus infections COVID-19 cross-sectional defined EMA enrolled fear female female gender General population higher risk increase in individual Insomnia Iran ISI Material and Method objective outbreak participant Participants phenotype Prevalence prevalent problem Quality of life questionnaire Result SARS-CoV-2 severity Sleep Sleep Initiation and Maintenance Disorders Symptom were excluded [DOI] 10.5935/1984-0063.20200087 PMC 바로가기 [Article Type] Original Article
Capsid integrity quantitative PCR to determine virus infectivity in environmental and food applications – A systematic reviewFull Paper Published on 2020-12-092022-10-28 Journal: Water Research X [Category] COVID-19, [키워드] (6) azo dye Abstract Activation approach Azo dye benefit capsid causes Concentration condition conditions COVID-19 pandemic Dengue fever determine disease effective Efficacy EMA Endemic False negative genomic help higher efficiency identify Image inactivated include Infectious virus infectious viruses less limit measure Microbial contamination molecular Outbreaks PCR assay peer-reviewed study PMA protocol protocols provided qPCR quantitative PCR recommendation reduction risk systematic review temperature Transmission Variation viability viral outbreak virus virus infectivity water quality [DOI] 10.1016/j.wroa.2020.100080 PMC 바로가기 [Article Type] Full Paper
Hepatic Disorders With the Use of Remdesivir for Coronavirus 2019코로나바이러스 2019에 렘데시비르를 사용한 간 장애Multicenter Study Published on 2020-11-012022-09-11 Journal: Clinical gastroenterology and hepatology : the off [Category] Coronavirus, SARS, 비임상, [키워드] Adverse drug reaction adverse event adverse events Aminotransferase antiviral activity available data Bilirubin breath broad spectrum Cell culture cell cultures clinical development clinical trials Cohort studies cohort study compassionate-use coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients disorder double-blind drug drug reaction Drug-induced liver injury elevated EMA European Medicines Agency FDA food healthy volunteer healthy volunteers hepatic hepatic enzyme hepatic enzymes hepatotoxicity hospital human coronavirus increase Infection Intravenous remdesivir investigator investigators Liver injury mouse model Mouse models nucleotide Patient patients hospitalized patients with COVID-19 Placebo placebo recipient placebo recipients placebo-controlled clinical trial proportion raised Randomized recipient Remdesivir reported respiratory safety profile Severe acute respiratory syndrome Severe Acute Respiratory Syndrome-associated Coronavirus 2 severe coronavirus disease severe COVID-19 treated Treatment [DOI] 10.1016/j.cgh.2020.07.050 PMC 바로가기 [Article Type] Multicenter Study
Elements of Regulatory Dissonance: Examining FDA and EMA Product Labeling of New Vaccines (2006–2018)Article Published on 2020-10-132024-09-04 Journal: Vaccine [Category] 대상포진, [키워드] EMA FDA harmonisation immunisation Regulatory Vaccines [DOI] 10.1016/j.vaccine.2020.09.067 PMC 바로가기 [Article Type] Article
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?Pharmacology Published on 2020-09-232022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] adjuvant Allium benefit/risk assessment Clinical data collected conditions coronavirus (2019-nCoV) COVID-19 COVID-19 pandemic COVID-19 patient current disease drug drugs Echinacea Efficacy and safety EMA Eucalyptus globulus evaluated Evidence expected Fever flu Frame glycyrrhiza healthy Hedera helix Herbal herbal medicine herbal medicines IMPROVE include indicated Magnolia Medicine Mikania Mild offer Paracetamol Patient Pelargonium positive Preclinical Prevent recommendation respiratory diseases Result safety margin Sambucus selected Self-isolation Self-management Symptom the WHO therapeutic approaches Treatment underlying conditions while widespread Zingiber [DOI] 10.3389/fphar.2020.581840 PMC 바로가기 [Article Type] Pharmacology
Sleep quality and mood symptoms in conscripted frontline nurse in Wuhan, China during COVID-19 outbreak A cross-sectional study5000 Published on 2020-06-262022-10-30 Journal: Medicine [Category] COVID-19, [키워드] Anxiety anxiety symptom anxiety symptoms Comprehensive conducted coronavirus disease COVID-19 COVID-19 outbreak cross-sectional Depression EMA GAD-7 Generalized hypnotics IMPROVE latency measure nightmare Nurse Nurses participant patients with COVID-19 PHQ-9 Pittsburgh Prevalence Prevent problems reported scale significantly Sleep sleep quality suffered Symptom Symptoms were measured Wuhan Wuhan, China [DOI] 10.1097/MD.0000000000020769 PMC 바로가기 [Article Type] 5000
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccinesGuest Editorial Published on 2020-05-232022-10-28 Journal: Archives of Toxicology [Category] COVID-19, MERS, SARS, [키워드] accelerated antibody approach approaches biological processe carcinogenicity country COVID-19 Critical drug Drug discovery Efficacy EMA epitope European Medicines Agency feature Health Laboratory limitation Molecular biology Organoid pandemic pathogen predict resource SARS-CoV2 supplementary material Vaccine virus virus infectivity [DOI] 10.1007/s00204-020-02787-2 PMC 바로가기 [Article Type] Guest Editorial
Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell lineArticle Published on 2013-11-192023-06-24 Journal: Vaccine [Category] 신종인플루엔자, [키워드] 1:2 dilution at toi 1:2dil 50% tissue culture infective dose A/PR/8 A/Puerto Rico/8/34 carcinoembryonic antigen-related cell adhesion molecule 6 CEACAM6 EMA European Medicines Agency FDA FITC flow cytometry fluorescein isothiocyanate Food and Drug Administration Glasgow minimum essential medium GMEM HA Haemagglutinin hours post infection hpi Influenza MAD Madin–Darby canine kidney MDCK MDCK suspension cells median of absolute deviation Medium exchange MOI multiplicity of infection phosphatidylinositide 3-kinase PI3K TCID(50) TdT dUTP nick end labelling time of infection toi Trypsin activity TUNEL Vaccine w/oME with medium exchange without medium exchange. wME [DOI] 10.1016/j.vaccine.2013.09.051