Glycolysis – Page 5 – Communicable Diseases Research

Metabolic requirements of NK cells during the acute response against retroviral infection

Article

Published on 2021-09-102022-10-29
Journal: Nature Communications [Category] Coronavirus, SARS,

2‐Deoxy‐ d ‐glucose exploits increased glucose metabolism in cancer and viral‐infected cells: Relevance to its use in India against SARS‐CoV ‐2

Article

Published on 2021-09-022023-06-15
Journal: Iubmb Life [Category] MERS, SARS,

[키워드] 2‐deoxy‐d‐glucose or 2‐DG Cancer cellular glucose metabolism ER stress Glycolysis SARS‐CoV‐2 viruses
[DOI] 10.1002/iub.2546 PMC 바로가기

Host metabolic reprogramming in response to SARS-CoV-2 infection: A systems biology approach

SARS-CoV-2 감염에 대한 숙주 대사 재프로그래밍: 시스템 생물학 접근법

Article

Published on 2021-09-012022-09-11
Journal: Microbial pathogenesis [Category] SARS, 신약개발, 유전자 메커니즘,

[키워드] alteration Amino acid amino acid metabolism Analysis analyzed Antiviral approach Bronchoalveolar lavage fluid cell line change COVID-19 dysregulation effective expression pattern glutathione glutathione metabolism Glycolysis Host host-pathogen interaction hypothese hypotheses immunomodulation in vitro study lipid metabolism lung lung biopsy metabolic gene metabolic genes metabolism metabolite mitochondrial mitochondrial metabolism mononuclear cells Nasopharyngeal swab network model nucleotide Pathogenesis pathogenesis of SARS-CoV-2 Pathways Patient Peripheral blood Peripheral blood mononuclear cells polyamine Polyamine metabolism polyamine synthesis redox Redox homeostasis reducing Replication reporter resource SARS-CoV-2 SARS-COV-2 infection survival Systems biology transcriptomic data transcriptomics Treatment strategies understanding viral titer viral titers Warburg effect.
[DOI] 10.1016/j.micpath.2021.105114 PMC 바로가기 [Article Type] Article

Immunometabolic signatures predict risk of progression to sepsis in COVID-19

Research Article

Published on 2021-08-302022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] 95%CI amino acid metabolism Analysis AUC chemokines Clinical finding correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill patients diabetes Diagnosis disease dysregulation early diagnosis Glycolysis help hyperinflammation IL-6 implementation In-hospital individuals Inflammatory cytokines lipid metabolism metabolism metabolite metabolomics Mild mild patient mitochondrial metabolism Mortality multisystemic neutrophil activation NLR Non-COVID-19 patients who survived plasma sample polyamine synthesis predict Prognosis progression quantified risk sensitivity Sepsis sepsis patient septic septic patients Severe patient severity specificity Treatment Type
[DOI] 10.1371/journal.pone.0256784 PMC 바로가기 [Article Type] Research Article

A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19

Public Health

Published on 2021-07-282022-10-31
Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS,

[키워드] accelerate ACE2 ACE2 receptor Affect aggravate airways alveolar cells article ASL blood glucose carbohydrates Cell cell damage cell death cells Combination Complication computational modeling Concentration condition COVID-19 Critical care Cytokine storm database diagnostic disease disease severity dysregulated dysregulation Effect elevated Elevation evade Evidence explain facilitate feasibility Glucose glycemia glycemic control Glycolysis glycosylation hyper-inflammation hyperglycemia Hypothesis immune defense inactivation induce Infection infection process infections Inflammation information innate immune system involved Ketogenic diet knowledge Level lung Lungs machine learning model MOST multi-organ failure multiple mechanism pandemic potential treatments progression proportion provide pulmonary inflammatory response Quantitative reached replicate Replication Research risk role SARS-CoV-2 Severe case severe COVID-19 severity subsequent Symptoms tested the cytokine storm the disease the patient the SARS-CoV-2 Thrombotic events treatment strategy View viral infection Viral load virus weakened
[DOI] 10.3389/fpubh.2021.695139 PMC 바로가기 [Article Type] Public Health

Intragastric and atomized administration of canagliflozin inhibit inflammatory cytokine storm in lipopolysaccharide-treated sepsis in mice: A potential COVID-19 treatment

Research article

Published on 2021-07-012022-10-05
Journal: International immunopharmacology [Category] SARS, 치료법,

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

Research Article

Published on 2021-06-212022-10-31
Journal: eLife [Category] COVID-19, MERS, SARS,

Energy sources that fuel metabolic processes in protruding finger-like organelles

Review

Published on 2021-06-012023-07-13
Journal: The Febs Journal [Category] SARS,

[키워드] ATP-shuttle cilium COVID-19 flagellum Glycolysis Mitochondria olfactory sensory neuron oxidative phosphorylation photoreceptor sperm.
[DOI] 10.1111/febs.15620 [Article Type] Review

Glycolytic Metabolism Is Critical for the Innate Antibacterial Defense in Acute Streptococcus pneumoniae Otitis Media

당의 대사 경로는 급성 폐렴구균 중이염에서 선천적인 항균 방어에 중요하다.

Original Research

Published on 2021-04-192024-07-30
Journal: Frontiers in immunology [Category] 폐렴구균 감염증,

[키워드] Glycolysis hypoxia inducible factor-1α Innate immunity Neutrophils otitis media
[DOI] 10.3389/fimmu.2021.624775 PMC 바로가기 [Article Type] Original Research

Single-Cell RNA Sequencing Analysis of the Immunometabolic Rewiring and Immunopathogenesis of Coronavirus Disease 2019

2019년 코로나바이러스 질병의 면역대사 재배선 및 면역병인에 대한 단일 세포 RNA 시퀀싱 분석

Immunology

Published on 2021-04-142022-09-11
Journal: Frontiers in Immunology [Category] MERS, 바이오마커, 유전자 메커니즘, 진단,

[키워드] antibody secretion ATP13A3 ATP6V1B2 biological processe CD14 Cell cell population cell survival change contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Degradation differentiation elevated exacerbated expressed feature Glycolysis hyperinflammation Immune cell immune cells immune dysfunction Inflammation inhibit investigated involved KMT2E LDHA lead lysine mechanism memory B cell memory B cells metabolic changes mild patients mono monocyte Monocytes mononuclear cell mononuclear cells NSD1 Pathways Patient PBMCs Peripheral blood Peripheral blood mononuclear cells PGD PKM Plasma cell Plasma cells plasmablast plasmablasts progression promoted reduced RNA sequencing data SETD2 severe COVID-19 severe disease Severe patient severe patients signaling pathways Single-cell RNA sequencing survival TKT Transcription
[DOI] 10.3389/fimmu.2021.651656 PMC 바로가기 [Article Type] Immunology