Granzyme B Cleaves Multiple Herpes Simplex Virus 1 and Varicella-Zoster Virus (VZV) Gene Products, and VZV ORF4 Inhibits Natural Killer Cell Cytotoxicity그랜자임 B는 여러 가지 단순 포진 바이러스 1 및 수두-대상포진 바이러스(VZV) 유전자 산물을 절단하며, VZV ORF4는 자연 살해 세포의 세포독성을 억제한다.Article Published on 2019-10-292023-05-31 Journal: Journal of Virology [Category] Fulltext, 대상포진, 두창, 수두, 홍역, [키워드] granzyme B Herpes simplex virus (HSV) natural killer (NK) cells. Varicella zoster virus (VZV) [DOI] 10.1128/JVI.01140-19 PMC 바로가기
STAT3 directly regulates NKp46 transcription in NK cells of HBeAg-negative CHB patientsArticle Published on 2019-10-012023-06-19 Journal: Journal of leukocyte biology [Category] B형 간염, [키워드] CD107a CHB granzyme B IFN-γ Natural killer cells NKp46 perforin STAT3 [DOI] 10.1002/JLB.2A1118-421R
Activated cytotoxic T cells within zoonotic cutaneous leishmaniasis lesionsOriginal Research Published on 2019-04-172023-05-31 Journal: Immunity, Inflammation and Disease [Category] Fulltext, 조류인플루엔자, [키워드] Cytotoxic Cells granulysin granzyme B IFN‐γ Leishmania major Leishmaniasis lesion [DOI] 10.1002/iid3.240 PMC 바로가기 [Article Type] Original Research
Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector FunctionImmunology Published on 2019-04-102022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, [키워드] ameliorated caused CD11b Cell cytokine cytotoxicity deficiency degranulation development domain effector evidenced exhibited expressed expression fulminant hepatitis function granzyme B Hepatitis hepatitis B homologous identify IFN-γ Immune-mediated in vitro Infection investigated Kctd9 knockout mice Lineage liver Liver damage manifested maturation mechanism mice murine hepatitis virus natural natural killer NK cell NK cell function NK cells Patient phenotype potassium channel progression proliferative proportion reduction in Regulation selective supported survival transcription factors tumor cell wild-type [DOI] 10.3389/fimmu.2019.00744 PMC 바로가기 [Article Type] Immunology
Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of ProtectionOriginal Research Published on 2018-11-132023-05-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] Fulltext, 조류인플루엔자, [키워드] Correlate of protection granzyme B Leishmania major Re-infection specific-cytotoxicity [DOI] 10.3389/fcimb.2018.00397 PMC 바로가기 [Article Type] Original Research
M2SR, a novel live Single Replication influenza virus vaccine, provides effective heterosubtypic protection in miceArticle Published on 2016-09-232023-06-23 Journal: Vaccine [Category] 신종인플루엔자, [키워드] CD8 T cell granzyme B IFN-γ M2-deficient mucosal antibody single replication sterilizing immunity universal influenza vaccine [DOI] 10.1016/j.vaccine.2016.08.061 PMC 바로가기 [Article Type] Article