healthy individuals – Page 5 – Communicable Diseases Research

Application and Validation of SARS-CoV-2 RBD Neutralizing ELISA Assay

SARS-CoV-2 RBD 중화 ELISA 분석의 적용 및 검증

Article

Published on 2022-02-282022-09-11
Journal: Archives of Razi Institute [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

Increased Expression of Tim-3 Is Associated With Depletion of NKT Cells In SARS-CoV-2 Infection

Tim-3의 발현 증가는 SARS-CoV-2 감염에서 NKT 세포의 고갈과 관련이 있습니다

Immunology

Published on 2022-02-162022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis Apoptosis binding caspase caused CD147 CD26 Cell circulating coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients CTLA-4 DCs decrease demonstrated dendritic cell dendritic cells Depletion disease severity dysfunction expressed expression expression level Genes healthy individuals IFN-γ IL-10 IL-12 IL-4 immune responses Immunopathogenesis implication Increased increased expression LAG-3 large cohort mechanism mitochondrial mitochondrial gene mitochondrial genes natural killer NKT NKT cell NKT cells outcome patients with COVID-19 PD-1 positively correlated Prognosis progression stage promote receptor receptors respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike scRNA-seq secrete secreted Sequencing analysis severe acute respiratory syndrome Coronavirus severity and prognosis Single-cell RNA sequencing stages therapeutic strategy TIM-3 up-regulated
[DOI] 10.3389/fimmu.2022.796682 PMC 바로가기 [Article Type] Immunology

Bean Extract-Based Gargle for Efficient Diagnosis of Active COVID-19 Infection Using Rapid Antigen Tests

신속한 항원 테스트를 사용하여 활성 COVID-19 감염의 효율적인 진단을 위한 콩 추출물 기반 가글

Research Article

Published on 2022-02-162022-09-10
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] Ag-RDT Ag-RDTs Alpha alpha and delta variants alternative analyzed Antigen Asymptomatic Bean canavalin clinical trial Concentration COVID-19 COVID-19 cases COVID-19 patient COVID-19 patients Delta delta variant Delta variants Detachment Detection sensitivity diagnostic diagnostic test domain early diagnosis efficient ENhance evaluated Evidence gargle hACE2 healthy individual healthy individuals ingredient initial intermolecular interaction intermolecular interactions less management Mass screening Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs oral virus Patient patients hospitalized Physicochemical properties Rapid Rapid diagnostic test RDTs RT-PCR saliva specimen saliva specimens salivary SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike proteins SARS-CoV-2 variant screening process sensitivities sensitivity significantly Specificities specificity Spike proteins symptomatic symptomatic and asymptomatic Test tested the SARS-CoV-2 variants Viral Viral detection virus
[DOI] 10.1128/spectrum.01614-21 PMC 바로가기 [Article Type] Research Article

Response to Vaccines in Patients with Immune-Mediated Inflammatory Diseases: A Narrative Review

Review

Published on 2022-02-152022-10-28
Journal: Vaccines [Category] COVID-19,

[키워드] activating acute respiratory syndrome Affect antibody appear attenuate B-cell biologic Biologic therapy coronavirus CTLA-4 described dose Efficacy evaluated fusion protein healthy individuals IL-17 IL-6 immune response immune system Immune-mediated inflammatory disease Immune-mediated inflammatory diseases immunosuppressants immunosuppressive immunosuppressive drugs impair increased risk Infection Inflammatory bowel disease inhibitor inhibitors integrin Interleukins knowledge limit Live attenuated vaccine narrative Necrosis pathogenic Patient patients patients receiving treatment patients treated protective immune response protective response recommendation reduced replicate response responses review rheumatoid arthritis risk of infection Safe SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 vaccine severe disease Therapies therapy TNF treat Treatment vaccination Vaccine vaccine response Vaccines
[DOI] 10.3390/vaccines10020297 PMC 바로가기 [Article Type] Review

Diagnostic performance and clinical feasibility of a novel one-step RT-qPCR assay for simultaneous detection of multiple severe acute respiratory syndrome coronaviruses

다중 심각한 급성 호흡기 증후군 코로나 바이러스의 동시 검출을위한 새로운 1 단계 RT-QPCR 분석의 진단 성능 및 임상 적 타당성

Original Article

Published on 2022-02-092022-09-10
Journal: Archives of Virology [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, 치료기술, 치료제,

[키워드] Acute respiratory infection acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis can be used caused cell culture supernatants Chain Reaction circulating variant clinical outcomes clinical sample coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CoVs Critical cross-reaction Diagnosis early diagnosis evaluated event feasibility genes encoding healthy individuals human CoV human CoVs humans IMPROVE in vitro infect Laboratory laboratory diagnosis limit of detection majority membrane mild respiratory symptoms mRNA multiplex RT-qPCR nasal swab Other other coronaviruses Other respiratory viruses patients with COVID-19 polymerase chain polymerase chain reaction Protein qPCR assay Quantitative reaction respiratory respiratory infection Respiratory samples respiratory symptoms respiratory viruses reverse transcription RNA RT-qPCR SARS-CoV-2 SARS-like CoV SARS-like CoVs SARS-related CoV severe acute respiratory syndrome Coronavirus sputum samples supplementary material TCID Transmission zoonotic origin
[DOI] 10.1007/s00705-022-05383-0 PMC 바로가기 [Article Type] Original Article

NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals

NK 세포 빈도, 기능 및 BNT162b2 mRNA 항 SARS-CoV-2 예방 접종을 받은 건강하고 면역이 약한 개인에서 백신 결과와 상관 관계

Research Article

Published on 2022-02-082022-09-12
Journal: Molecular Medicine [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] adaptive immune responses anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies baseline BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination BNT162b2 mRNA vaccine Cancer characterized clinical material clinical trial Course COVID-19 Day description Effect EudraCT frequencies Frequency healthy healthy individuals immune cells immune response immune responses Immunocompromised immunocompromised individual Immunocompromised patient Immunocompromised patients in healthy individual Innate immune cells Innate immunity mRNA mRNA vaccination mRNA vaccine mRNA-based NK cell NK cells NKG2C non-randomized Open-label outcome Peripheral blood Phenotypes positive correlation preserved Prospective clinical trial Registered Result SARS-CoV-2 supplementary material Trial registration vaccination Vaccine vaccine trial viral infections
[DOI] 10.1186/s10020-022-00443-2 PMC 바로가기 [Article Type] Research Article

Fungal Colonization and Infections—Interactions with Other Human Diseases

Review

Published on 2022-02-062022-10-28
Journal: Pathogens [Category] COVID-19,

Hidden fraction of Polish population immune to SARS-CoV-2 in May 2021

2021년 5월에 SARS-CoV-2에 면역된 폴란드 인구의 숨겨진 부분

Research Article

Published on 2022-02-032022-09-12
Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] ACE2 Anti-RBD IgG anti-SARS-CoV-2 antibodies Antigen antigens Asymptomatic can not collected convalescent COVID-19 COVID-19 pandemic cross-reactivity diagnosed estimation exclusion fraction HCoV HCoV 229E healthy individual healthy individuals herd immunity hospitalized COVID-19 patient hospitalized COVID-19 patients IgA IgA antibodies IgA antibody IgG immune Immunity individual Infection infections investigated Lower majority MERS-CoV modeling NL63 other coronaviruses pandemic Patient patients Population population immunity Population screening positive positive controls Protein public health Quantitative RBD Registered SARS-CoV SARS-CoV-2 SARS-CoV-2 antigens SARS-CoV-2-specific IgG sera serum sample serum samples spike subject tested vaccination vaccination against COVID-19 Vaccinations virus virus-neutralizing Virus-specific IgG
[DOI] 10.1371/journal.pone.0253638 PMC 바로가기 [Article Type] Research Article

Fingolimod impairs inactivated vaccine (CoronaVac)-induced antibody response to SARS-CoV-2 spike protein in persons with multiple sclerosis

Fingolimod는 다발성 경화증 환자에서 SARS-CoV-2 스파이크 단백질에 대한 불활성화 백신(CoronaVac) 유도 항체 반응을 손상시킵니다.

Article

Published on 2022-02-012022-09-12
Journal: Multiple sclerosis and related disorders [Category] COVID19(2023년), MERS, SARS, 진단,

Psychological Effects of Online-Based Mindfulness Programs during the COVID-19 Pandemic: A Systematic Review of Randomized Controlled Trials

코로나19 팬데믹 기간 동안 온라인 기반 마음챙김 프로그램의 심리적 효과: 무작위 통제 시험의 체계적인 검토

Review

Published on 2022-01-312022-09-10
Journal: International Journal of Environmental Research an [Category] SARS, 임상,