IFITM3 , TLR3 , and CD55 Gene SNPs and Cumulative Genetic Risks for Severe Outcomes in Chinese Patients With H7N9/H1N1 pdm09 InfluenzaArticle Published on 2017-07-012023-06-14 Journal: The Journal of Infectious Diseases [Category] Fulltext, 신종인플루엔자, [키워드] TLR3. IFITM3 Influenza outcomes SNP [DOI] 10.1093/infdis/jix235 PMC 바로가기
No Correlation of the Disease Severity of Influenza A Virus Infection with the rs12252 Polymorphism of the Interferon-Induced Transmembrane Protein 3 GeneArticle Published on 2017-01-012023-06-23 Journal: Intervirology [Category] 신종인플루엔자, [키워드] 2009 influenza A pandemic Epidemiology Genetic polymorphism H1N1 IFITM3 Interferon-induced transmembrane protein 3. [DOI] 10.1159/000479087
IFITM Proteins Inhibit Entry Driven by the MERS-Coronavirus Spike Protein: Evidence for Cholesterol-Independent MechanismsArticle Published on 2014-09-262022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] 293T cell 293T cells A549 cells Analysis antiviral activity blockade cellular cellular entry cholesterol circulating contribute coronavirus Coronavirus infection correlation defined Efficiency expression level host cell human coronaviruses 229E humans IFITM IFITM3 IFITMs Infection Influenza virus inhibit inhibited investigated less mechanism MERS MERS-CoV mice Middle East modulation NL63 Protein Proteins respiratory syndrome coronavirus retroviral vector SARS SARS-CoV spike susceptibility transmembrane viral entry viruses [DOI] 10.3390/v6093683 PMC 바로가기 [Article Type] Article
S -Palmitoylation and Ubiquitination Differentially Regulate Interferon-induced Transmembrane Protein 3 (IFITM3)-mediated Resistance to Influenza Virus *Article Published on 2012-06-012023-06-23 Journal: The Journal of Biological Chemistry [Category] 신종인플루엔자, [키워드] IFITM3 Influenza virus interferon Intramembrane Domain Membrane proteins protein palmitoylation ubiquitination [DOI] 10.1074/jbc.M112.362095 PMC 바로가기
Distinct Patterns of IFITM-Mediated Restriction of Filoviruses, SARS Coronavirus, and Influenza A VirusResearch Article Published on 2011-01-062022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, [키워드] Acidic Author bypasse bypassed cathepsin L Cell cellular cellular tropism circumvent compared Control cytoplasm described did not reduce Ebola Ebola virus Endocytic pathway ENhance example Express expression Factors Filovirus glycoprotein highly pathogenic IAV IFITM IFITM1 IFITM3 indicate Infection infectious influenza A virus inhibit inhibited innate immune system interfere late stage less limit lysosomal modulate murine observation pathogenic viruses pattern plasma membrane Protein Proteins pseudovirions receptor Replication restrict restriction restriction factor SARS Coronavirus SARS-CoV transmembrane transmembrane protein Treatment viral replication virion virus viruses [DOI] 10.1371/journal.ppat.1001258 PMC 바로가기 [Article Type] Research Article