Prognostic value of neutrophil-to-lymphocyte ratio, lactate dehydrogenase, D-dimer, and computed tomography score in patients with coronavirus disease 2019코로나 바이러스 질환 2019 환자에서 호중구 대 림프구 비율, 젖산 탈수소 효소, D- 이미머 및 컴퓨터 단층 촬영 점수의 예후 값Research Paper Published on 2021-09-152022-09-01 Journal: Aging (Albany NY) [Category] 진단, [키워드] Admission baseline baseline data Chest computed tomography Clinical outcome clinical outcomes collected Combination Combined Computed tomography coronavirus disease Coronavirus disease 2019 COVID-19 CT score D-dimer Diagnosis enrolled evaluated groups IMPROVE independent independent predictor independent predictors Laboratory laboratory findings laboratory-confirmed Laboratory-confirmed COVID-19 Lactate lactate dehydrogenase LDH Logistic regression lymphocyte multivariate logistic regression neutrophil Neutrophil-to-lymphocyte ratio NLR on admission Patient patients Prognosis sensitivity serum severe COVID-19 severe disease severity and prognosis severity of COVID-19 was used [DOI] 10.18632/aging.203501 PMC 바로가기 [Article Type] Research Paper
Immunological Profiling of COVID-19 Patients with Pulmonary Sequelae폐 후유증이 있는 COVID-19 환자의 면역학적 프로파일링Research Article Published on 2021-09-072022-09-10 Journal: mBio [Category] MERS, 바이오마커, [키워드] accumulation activated Alpha B cell B cells CD27 CD28 CD4 CD57 CD8 Cell cellular immunity Characteristics characterized comparable coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient discharge downregulation evaluated excessive secretion exhibited feature functional granzyme granzyme B IFN-γ IL-17A IL-2 IL-4 immune Immune cell immune cells Immunity immunological immunosuppressive independent predictor independent predictors interferon gamma interleukin intrinsically involved lesions marker multiparametric flow cytometry natural killer Necrosis NK cell NK cells NKT organ damage Patient perforin Profiling proportion pulmonary pulmonary sequelae radiological recruited rehabilitation secreting senescent short-lived survivor T cell T cells terminal differentiation TNF-α tumor necrosis tumor necrosis factor alpha two groups upregulation [DOI] 10.1128/mBio.01599-21 PMC 바로가기 [Article Type] Research Article
Oxidant and antioxidant balance in patients with COVID-19COVID-19 환자의 산화 및 항산화 균형Article Published on 2021-09-012022-09-11 Journal: Pediatric pulmonology [Category] SARS, 바이오마커, [키워드] Adults albumin albumin level analyzed antioxidant balance candidate caused children Clinical course coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 case COVID-19 group demographic characteristics Diagnosis disease severity Disulfide evaluate evaluated functional group groups healthy healthy children healthy controls immune system independent predictor independent predictors Ischemia mechanism Oxidant oxidative oxidative stress pandemic parameter patients with COVID-19 pediatric pediatrics predictor serum severe disease course severity significantly lower Stress thiol thiols. Viral viral infection with COVID-19 [DOI] 10.1002/ppul.25549 PMC 바로가기 [Article Type] Article
Outcomes of COVID-19 in Patients With Cancer: A Closer Look at Pre-Emptive Routine Screening Strategies암 환자의 COVID-19 결과: 선제적 정기 검진 전략 자세히 살펴보기Observational Study Published on 2021-09-012022-09-11 Journal: JCO oncology practice [Category] SARS, 임상, 치료기술, 치료제, [키워드] Absolute lymphocyte count acute respiratory syndrome Admission age all-cause mortality asymptomatic patient asymptomatic patients benefit Cancer center Chemotherapy clinical suspicion Cohort cohort of patient conducted coronavirus COVID-19 diagnosed diagnosed with COVID-19 FIVE groups Hospital admission Hospitalization independent predictor independent predictors Infection inpatient admission intensive care intensive care unit admission lymphocyte Mayo Clinic Mortality multisite multivariable analysis no significant differences not significantly different observational study Odds ratio outcome Patient Patients with cancer Primary outcome prospective observational study routine Screening secondary Secondary outcomes severe acute respiratory syndrome Coronavirus Strategy surgical therapy [DOI] 10.1200/OP.21.00177 PMC 바로가기 [Article Type] Observational Study
Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort—correlation with disease characteristics선택된 독일 환자 코호트에서 COVID-19 환자의 혈청학적 및 바이러스 유전적 특징 - 질병 특성과의 상관관계Original Article Published on 2021-09-012022-09-11 Journal: GeroScience [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, [키워드] affected age Analysis anti-N IgG anti-S Anti-S1 anti-S2 anti-SARS-CoV-2 antibody Anti-spike antibody average blood collection Blood Group cardiovascular change Characteristics characterized Clinical characteristics Cluster Clusters Cohort concomitant disease Coronavirus-2 correlation COVID-19 COVID-19 disease characteristics determined by disease ELISA feature Genetic Hospitalization host-virus interaction host-virus interactions humoral immune response IgG IgG and IgM IgG level IgM independent predictor independent predictors Infection investigated less Local Multiple regression Non-synonymous Nsp12 nucleocapsid protein nucleotide occurred ORF3a outbreak overweight pandemic Patient patients patients with COVID-19 Phylogenetic analysis prevalent reactivity representing SARS Coronavirus SARS-CoV-2 SARS-CoV-2 variants SARS-CoV-2-infected patient selected Sequencing sequencing data Serological testing serology significantly Single nucleotide variant supplementary material Viral genetics virus whole genome Whole genome sequencing [DOI] 10.1007/s11357-021-00443-w PMC 바로가기 [Article Type] Original Article
Liver involvement in children with SARS-COV-2 infection: Two distinct clinical phenotypes caused by the same virusSARS-COV-2 감염 아동의 간 침범: 동일한 바이러스로 인한 두 가지 뚜렷한 임상 표현형Article Published on 2021-09-012022-09-11 Journal: Liver international : official journal of the Inte [Category] SARS, 치료기술, [키워드] acute liver failure Acute liver injury acute liver injury and MISC acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Adults age Alanine alanine aminotransferase ALT association bivariate analysis black Black race C-reactive protein caused Characteristics children chronic liver disease clinical phenotype Cohort coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 ALI in children defined dysfunction elevated elevated ALT Gender Hispanic Hospitalization ICU Immunocompromised immunocompromised status increased risk independent predictors Infection Inflammatory liver Liver disease liver failure liver involvement in SARS-CoV2. male manifestation MIS-C Mortality Multiorgan dysfunction multivariable logistic regression obesity outcome Patient positive Protein regression models respiratory Retrospective study SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV2 Severe acute respiratory syndrome severe disease significantly higher transaminase virus with COVID-19 [DOI] 10.1111/liv.14887 PMC 바로가기 [Article Type] Article
High-Sensitivity Cardiac Troponin T for the Detection of Myocardial Injury and Risk Stratification in COVID-19COVID-19에서 심근 손상 및 위험 계층화 감지를 위한 고감도 심장 트로포닌 TObservational Study Published on 2021-08-052022-09-11 Journal: Clinical Chemistry [Category] SARS, 바이오마커, 임상, [키워드] 95% CI adjusted adverse event adverse events cardiac Cardiac arrest cardiac troponin Composite conducted COVID-19 COVID-19 patient cTnT detection facilitate high sensitivity cardiac troponin T higher risk Hospitalization Implications In-hospital increase independent predictor independent predictors Injury Limited mechanical ventilation Mortality MOST multicenter Myocardial Myocardial infarction myocardial injury Negative predictive value Patient Predictive value presenting Prognosis prognostic Respiratory failure retrospective risk stratification sensitivity Shock troponin T while [DOI] 10.1093/clinchem/hvab062 PMC 바로가기 [Article Type] Observational Study
Baseline characteristics and changes of biomarkers in disease course predict prognosis of patients with COVID-19질병 과정에서 바이오 마커의 기준 특성 및 변화 COVID-19 환자의 예후를 예측합니다.Observational Study Published on 2021-08-012022-08-31 Journal: Internal and Emergency Medicine [Category] MERS, 바이오마커, 임상, [키워드] age Analysis baseline baseline characteristics Biomarker Biomarkers blood cell C-reactive protein C-reactive protein (CRP change changes Characteristics characterized Clinical data collected coronavirus coronavirus disease Course COVID-19 COVID-19 patient CRP D-dimer declining disease course endpoints evaluate identify IL-6 IL-6 level IL-6 levels independent predictor independent predictors Inpatient Inpatients interleukin interleukin-6 laboratory data leukocyte Leukocyte count lymphocyte management marker multivariate Cox regression N-terminal neutrophil neutrophil counts Non-survivors Older age outbreak Patient patient death patients patients with COVID-19 peptide poor prognosis predict Predictive Predictive value predictor prognosis of patient Prognostic value Protein protein levels the disease TnI troponin troponin I Troponin I. WBC were used White blood cell with COVID-19 Wuhan Wuhan, China [DOI] 10.1007/s11739-020-02560-4 PMC 바로가기 [Article Type] Observational Study
Prognostic significance of cardiac injury in COVID-19 patients with and without coronary artery disease관상동맥 질환이 있거나 없는 COVID-19 환자에서 심장 손상의 예후적 의미Multicenter Study Published on 2021-08-012022-09-11 Journal: Coronary artery disease [Category] 바이오마커, [키워드] 95% CI 95% confidence interval Acute kidney injury acute respiratory distress acute respiratory distress syndrome Admission age Analysis CAD cardiac injury Characteristics clinical Clinical characteristics Clinical outcome collected consecutive patient consecutive patients Coronary artery Coronary artery disease COVID-19 COVID-19 patient COVID-19 patients CRP levels Diagnosis disease electronic medical records elevated Frequency high mortality hospitalized patient ICU independent predictor independent predictors Injury Laboratory laboratory findings male median age medical records Mortality mortality rate mortality risk Multivariate analysis on admission outcome Patient patients with COVID-19 predicted prognostic required respiratory distress Respiratory distress syndrome Retrospective study risk factor Risk factors subgroup analysis syndrome the median treated with COVID-19 [DOI] 10.1097/MCA.0000000000000914 PMC 바로가기 [Article Type] Multicenter Study
Global burden of acute myocardial injury associated with COVID-19: A systematic review, meta-analysis, and meta-regressionSystematic Review / Meta-analysis Published on 2021-07-282022-10-04 Journal: Annals of Medicine and Surgery [Category] 바이오마커, 진단, [키워드] article Case report Clinical outcome conducted Coronary artery correlation COVID-19 COVID-19 infection COVID-19 pandemic determinants determine diagnostic disease evaluated Evidence hypertension incidence independent independent predictor independent predictors Infection LILACS Meta-analysis meta-regression Methodological quality mitigating strategy Mortality Myocardial myocardial injury observational study outcome participant Patient patients with COVID-19 peer-reviewed Prevalence Prevent reliability Result Science Direct Seven sustained systematic review Topic were excluded [DOI] 10.1016/j.amsu.2021.102594 PMC 바로가기 [Article Type] Systematic Review / Meta-analysis