Interleukin-6 affects the severity of olfactory disorder: a cross-sectional survey of 148 patients who recovered from Omicron infection using the Sniffin’ Sticks test in Tianjin, ChinaArticle Published on 2022-10-012023-07-10 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), [키워드] COVID-19 interleukin-6 olfactory disorder omicron vaccination [DOI] 10.1016/j.ijid.2022.07.074
Kynurenine serves as useful biomarker in acute, Long- and Post-COVID-19 diagnosticsArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 치료기술, [키워드] Admission age Biomarker Blood Concentration concerning controls correlated COVID-19 COVID-19 monitoring CRP CRP value diagnosis and monitoring diagnostics disease Donor elevated group hospital Hospitalized hyperinflammation IL-6 immune system Inflammation inflammation diagnostics Inflammatory Inflammatory marker Inflammatory response innate immune response Innate immunity Inpatient interleukin-6 investigated involved Kynurenine kynurenine reference values. Long Long-COVID biomarkers long-lasting marker material P-value pathophysiology Patient patients with SARS-CoV-2 rehabilitation Saliva SARS-COV-2 infection sera serum significantly significantly higher subset Symptom syndrome the SARS-CoV-2 therapy were measured [DOI] 10.3389/fimmu.2022.1004545 PMC 바로가기
Immune-inflammatory biomarkers and the risk of cardiac injury in COVID-19 patients with diabetes: a retrospective cohort studyArticle Published on 2022-09-192022-11-15 Journal: Cardiovascular Diabetology [Category] 바이오마커, 진단, [키워드] 95% CI 95% confidence interval adjusted age Biomarker cardiac cardiac injury CD3 CD4 Clinical data collected Concentration conducted COVID-19 COVID-19 patient COVID-19 patients demographic data determine Diabetes Mellitus Diabetic diabetic patient diagnosed expected Gender Glucose high risk IgA IL-6 Immune-inflammatory biomarkers immunoglobulin A in-hospital mortality incidence independent risk factor induce Injury Inpatient Interaction interleukin-6 logistics Mortality myocardial damage outcomes parameter participant Patient plasma predictor regression analysis Renmin Hospital responses retrospective cohort study Retrospective study risk T cell university were assessed with COVID-19 Wuhan [DOI] 10.1186/s12933-022-01625-2 PMC 바로가기
A Dual-Encoded Bead-Based Immunoassay with Tunable Detection Range for COVID-19 Serum EvaluationArticle Published on 2022-09-122022-11-15 Journal: Angewandte Chemie (International ed. in English) [Category] 진단, [키워드] antigens Asymptomatic case C-reactive protein Circle Concentration Coronavirus 2019 COVID-19 COVID-19 antibody detection Disease progression help identify immunoassay Inflammatory biomarker interleukin-1β interleukin-6 magnitude Microfluidic Immunoassays multiplex Multiplexing nucleocapsid Patient procalcitonin Prognosis Range RCA Receptor binding domain Rolling Rolling circle amplification sensitivity serological treat Tunable Detection Range. [DOI] 10.1002/anie.202203706 PMC 바로가기
Different clinical features of children and adults in regional outbreak of Delta COVID-19Article Published on 2022-09-082022-11-16 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] Adult Adults analyzed Child children clinical clinical chemistry clinical feature collected college coronavirus disease COVID-19 Delta delta variant diarrhea Different clinical feature drug Hospitalized incidence Inflammatory Injury interleukin-6 less Liver injury Lymphocyte count Mild mild patient nasopharyngeal swabs no significant difference outbreak proportion SARS-CoV-2 serum creatinine significantly Symptom Symptom assessment Symptoms two groups Viral load [DOI] 10.1186/s12879-022-07707-6 PMC 바로가기
The impact of the COVID-19 pandemic on stress and other psychological factors in pregnant women giving birth during the first wave of the pandemicClinical Trial Published on 2022-09-052022-10-05 Journal: Reproductive Health [Category] SARS, 임상, [키워드] acute respiratory syndrome addition Administered affected Analysis Anxiety Anxiety Disorder anxiety level caused clinical collected concern coronavirus correlated correlation Course COVID-19 COVID-19 pandemic Department Depression disease Edinburgh Effect exceptional Factor First wave Germany Gynecology hormone Hospital admission Hospitalization IL-6 impairment increase in interleukin-6 loneliness Maternal Maternal bonding medium mental illness moderate Obstetric pandemic Patient Pregnancy pregnant women Psychological Psychosocial stress questionnaire recruited response resulting SARS-CoV-2 SARS-COV-2 infection scale Self-efficacy significant increase Sociodemographic Stress stress symptoms Trial registration university women [DOI] 10.1186/s12978-022-01493-9 PMC 바로가기 [Article Type] Clinical Trial
Lipoprotein(a) during COVID-19 hospitalization: Thrombosis, inflammation, and mortalityResearch article Published on 2022-09-012022-10-05 Journal: Atherosclerosis [Category] SARS, 바이오마커, [키워드] 1.26 adjusted hazard ratio Biomarker C-reactive protein Coronavirus disease 2019 COVID-19 COVID-19 hospitalization COVID-19 patients CRP D-dimer death discharge elevated hazard ratio hospital hospital discharge hypothese Inflammation Inflammatory biomarker interleukin-6 Mortality multivariable outcome Patient procalcitonin proinflammatory prothrombotic Result SARS-CoV-2 survival tested thrombotic university vaccination with COVID-19 [DOI] 10.1016/j.atherosclerosis.2022.07.015 [Article Type] Research article
A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation고염증을 동반한 COVID-19 폐렴의 치료를 위한 Clazakizumab의 무작위 이중 맹검 위약 대조 시험Clinical Trial Published on 2022-09-012022-09-12 Journal: Critical Care Medicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 1:1 accompanied added Bayesian benefit board changes Clazakizumab Clinical outcome clinical status Controlled COVID-19 COVID-19 disease Critical cumulative double-blinded dropped enrolled Frequency greater High-dose hospitalized patient hyperinflammation ICU ICU admission inhibitor Inpatient interleukin-6 intubation Logistic low-dose measurement monitoring Odds ratio outcome Patient patients patients hospitalized Placebo placebo-controlled Poisson regression model Primary outcome Randomized receiving recommendations risk Safety seamless secondary secondary outcome severe COVID-19 disease significantly suggested survival Trial Ventilation ventilator-free survival were used with COVID-19 [DOI] 10.1097/CCM.0000000000005591 PMC 바로가기 [Article Type] Clinical Trial
The predictive value of epicardial fat volume for clinical severity of COVID-19Research article Published on 2022-09-012022-10-05 Journal: Revista portuguesa de cardiologia [Category] 바이오마커, [키워드] adipose Admission age Analysis analyzed association C-reactive protein characteristic Clinical severity Computed tomography coronavirus disease COVID-19 CRP death disease severity Epicardial fat volume fat ferritin ferritin level hospitalized COVID-19 patients ICU ICU Patients IL-6 IL-6 level independent Inflammatory biomarker Inflammatory cytokine intensive care interleukin-6 male morbidity and mortality multivariate logistic regression objective occurred outcome Patient patients died patients with COVID-19 PCT positive correlation predict predicted Predictive primary composite endpoint procalcitonin Prognosis Result Retrospective study serum CRP severe complications significant level significantly higher tissue tomography Volume was determined were infected were measured with COVID-19 [DOI] 10.1016/j.repc.2021.05.016 [Article Type] Research article
Highlights of clinical and laboratory parameters among severe COVID-19 patients treated with tocilizumab: a retrospective observational studyArticle Published on 2022-09-012022-11-15 Journal: São Paulo medical journal = Revista paulista de medicina [Category] 진단, 치료기술, [키워드] Admission age Analysis analyzed C-reactive protein (CRP Chest Clinical characteristics Comparative conducted Coronavirus disease 2019 COVID-19 COVID-19 patient CRP CRP level CRS Cytokine release syndrome database died disease evaluate ferritin high mortality hospital Hospitalized IL-6 independent risk factor information interleukin-6 laboratory parameter Logistic regression analysis lymphocyte Mortality neutrophil no difference oxygen saturation Patient performed receiving Research retrospective severe COVID-19 patient Signal transduction significantly lower suppresse survival group survived the patient Tocilizumab tocilizumab administration treated Treatment Turkey WBC White blood cell [DOI] 10.1590/1516-3180.2021.0604.R1.23112021 PMC 바로가기