In Silico Analysis Predicts a Limited Impact of SARS-CoV-2 Variants on CD8 T Cell Recognition실리코 분석은 CD8 T 세포 인식에 대한 SARS-CoV-2 변이체의 제한된 영향을 예측합니다Article Published on 2022-04-272022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] Analysis antibody binding affinity bioinformatics bioinformatics & CD8 CD8 T cell CD8 T cell epitopes CD8 T cells Computational biology computational biology. Course COVID-19 pandemic Delta dominant variant epitope Epitopes HLA host immunity Immunity immunogenicity Impact infection with SARS-CoV-2 investigated Limited majority memory mutated Mutation new SARS-CoV-2 not altered pandemic predicted Protective raised Receptor binding Recognition reduced reported response SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants selection pressure sequence similarity specific mutation specific mutations Spike protein T cell T cell epitopes T cells the spike protein vaccination Vaccine variant variants [DOI] 10.3389/fimmu.2022.891524 PMC 바로가기 [Article Type] Article
Should routine risk reduction procedures for the prevention and control of pandemics become a standard in all oncological outpatient clinics? The prospective COVID-19 cohort study: protect-CoV전염병 예방 및 통제를 위한 일상적인 위험 감소 절차가 모든 종양 외래 환자 진료소에서 표준이 되어야 합니까? 전향적 COVID-19 코호트 연구: Protect-CoVArticle Published on 2022-04-102022-09-11 Journal: Medical oncology (Northwood, London, England) [Category] COVID19(2023년), SARS, 변종, [키워드] addition Asymptomatic Cancer cancer patient Care clinical care conducted COVID-19 COVID-19 case COVID-19 cohort COVID-19 pandemic early phase effective Effectiveness Epidemics hygiene immunology implementation Infusion Therapy investigated knowledge Limited measure outbreak Outpatient pandemic Pandemics Patient PCR testing positive pre-symptomatic prospective cohort prospective cohort study PROTECT protocol reduced risk of infection risk reduction Safe SARS-CoV-2 SARS-CoV-2 transmission therapy vulnerable population while [DOI] 10.1007/s12032-022-01700-4 PMC 바로가기 [Article Type] Article
The Effects of Migration and Limited Medical Resources of the Transmission of SARS-CoV-2 Model with Two Patches2개의 패치가 있는 SARS-CoV-2 모델 전파의 이주 및 제한된 의료 자원의 영향Article Published on 2022-04-042022-09-11 Journal: Bulletin of Mathematical Biology [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed Asymptomatic basic reproduction number Bifurcation Bifurcation and stability carried caused country detection rate disease Effect Elimination explain Human humans increase in initial introduced Limited Limited medical resources and migration Local mathematical mathematical model medical resource Medical resources Migration Model outbreak Prevalence Region regions SARS-CoV-2 SARS-CoV-2 model stability supply symptomatic the disease threshold value Transmission transmission of SARS-CoV-2 [DOI] 10.1007/s11538-022-01010-w PMC 바로가기 [Article Type] Article
Effectiveness of COVID-19 booster vaccines against COVID-19-related symptoms, hospitalization and death in England영국에서 COVID-19 관련 증상, 입원 및 사망에 대한 COVID-19 추가 백신의 효과Article Published on 2022-04-012022-09-11 Journal: Nature Medicine [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] Against all age group all age groups AstraZeneca BNT162b2 booster booster dose booster vaccination Booster vaccine Case-control ChAdOx1-S circulation coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19-related symptoms death delta variant dominant dose Effectiveness England Evidence evidence of Hospitalization individual Limited Messenger RNA Mild Moderna mRNA mRNA-1273 no evidence of of BNT162b2 offered Pfizer-BioNTech provide ranged second dose severe disease symptomatic symptomatic disease vaccination Vaccine [DOI] 10.1038/s41591-022-01699-1 PMC 바로가기 [Article Type] Article
SARS-CoV-2: low virus load on surfaces in public areasSARS-CoV-2: 공공 장소의 표면에 낮은 바이러스 부하Article Published on 2022-04-012022-09-11 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen can not coins company concerning condition conditions coronavirus coronavirus 2 detect disinfectant Europe excluded Germany greater Hamburg Healgen Houston Immunosuppression Infection Limited Low virus load performed press preventive measures Probability Public Public areas Rapid respiratory risk risk of infection risk of transmission SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Shanghai Siemens Healthineer Siemens Healthineers Swab swabs Test tested underlying disease underlying diseases USA Viral transmission virus virus load [DOI] 10.1007/s11356-022-18514-6 PMC 바로가기 [Article Type] Article
Treating the body to prevent brain injury: lessons learned from the coronavirus disease 2019 pandemic뇌 손상을 예방하기 위한 신체 치료: 2019년 코로나바이러스 전염병에서 배운 교훈Review Published on 2022-04-012022-09-11 Journal: Current opinion in critical care [Category] Coronavirus, COVID19(2023년), SARS, 치료기술, [키워드] Brain coronavirus disease COVID-19 discharge Doppler edema Electroencephalography emboli Encephalopathy epileptic Evidence Frontal Hypoxemia infrared spectroscopy Intervention intracranial pressure invasive large vessel Limited management marker morbidity morbidity and mortality near-infrared spectroscopy neurologic Neurological complication Neurological complications Occurrence optic nerve optic nerve sheath oxygen Oxygenation pandemic parameter patients with COVID-19 peripheral oxygen saturation Prevent Pupillometry recent reduce transcranial Doppler treating utility [DOI] 10.1097/MCC.0000000000000917 PMC 바로가기 [Article Type] Review
A phase 1/2 randomised placebo-controlled study of the COVID-19 vaccine mRNA-1273 in healthy Japanese adults: An interim report건강한 일본 성인을 대상으로 한 코로나19 백신 mRNA-1273의 1/2상 무작위 위약 대조 연구: 중간 보고서Clinical Trial Published on 2022-03-182022-09-12 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Administered adverse event AEs age AMED anti-SARS-CoV-2 immune response antibody ARMS baseline company conducted coronavirus COVID-19 COVID-19 vaccine mRNA-1273 demonstrated development dose ENCODE enrolled fatigue geometric healthy immune response immunogenicity Injection-site pain Interim report Intramuscular injection Japan Japanese Limited mRNA vaccine mRNA-1273 myalgia NAb neutralising antibody occurred outcome participant Participants pharmaceutical Placebo placebo-controlled study placebo-controlled trial randomised receive reported Safety safety profile SARS-CoV-2 SARS-COV-2 infection secondary outcome Spike protein stratified Takeda vaccination Vaccine [DOI] 10.1016/j.vaccine.2022.02.030 PMC 바로가기 [Article Type] Clinical Trial
Carbon peak and its mitigation implications for China in the post-pandemic eraArticle Published on 2022-03-022022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, SARS, [키워드] analyzed carbon China Chinese Climate sciences complex COVID-19 pandemic dataset develop Energy science and technology Environmental social sciences Impact implementation implication Implications intensity Limited machine learning approach MOST pandemic era Probability reduction targets unique Volume while [DOI] 10.1038/s41598-022-07283-4 PMC 바로가기 [Article Type] Article
SARS-CoV-2 mRNA vaccine induced higher antibody affinity and IgG titers against variants of concern in post-partum vs non-post-partum womenSARS-CoV-2 mRNA 백신은 산후 여성과 비 산후 여성에서 우려되는 변이체에 대해 더 높은 항체 친화도 및 IgG 역가를 유도했습니다.Article Published on 2022-03-012022-09-11 Journal: EBioMedicine [Category] MERS, SARS, 변종, 진단, [키워드] affinity Affinity maturation Amino acid amino acids antibody antibody affinity Antibody binding antibody neutralisation titres Beta both groups characterisation comparable controls countermeasure COVID-19 declined Delta described domain FDA groups help IgG titer immune response immune responses in both groups initiative knowledge Limited manuscript mRNA mRNA vaccine mutant neutralisation neutralisation titre neutralising ability plasma plasma antibody profile RBD SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants significantly higher spike supported sustained tested vaccination Vaccination strategies Vaccination strategy Vaccine vaccine-induced antibody response variants of concern VoC VOCs women [DOI] 10.1016/j.ebiom.2022.103940 PMC 바로가기 [Article Type] Article
SARS-CoV-2 vaccination elicits unconventional IgM specific responses in naïve and previously COVID-19-infected individualsSARS-CoV-2 예방 접종은 순진하고 이전에 COVID-19에 감염된 개인에서 비전통적인 IgM 특이적 반응을 이끌어냅니다.Article Published on 2022-03-012022-09-12 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] administration anti-S antibody BNT162b2 vaccine BTN162b2 vaccine Care Cohort collected coronavirus COVID-19 cross Department elicit expression foundation HCW Health IgG IgG antibody IgM IgM antibody Immunity immunologically individual Infection Italian Limited Ministry of Health naïve neutralization performed positive Protein pseudovirus recipient recruitment response Sample SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 vaccination second dose sera significantly more spike the SARS-CoV-2 titre titres vaccination vaccine dose vaccine response Verona virus-neutralizing [DOI] 10.1016/j.ebiom.2022.103888 PMC 바로가기 [Article Type] Article