Characterization of anti-MERS-CoV antibodies against various recombinant structural antigens of MERS-CoV in an imported case in ChinaOriginal Article Published on 2016-11-092022-10-31 Journal: Emerging Microbes & Infections [Category] Coronavirus, [키워드] antibody Antibody titer Antigen characterization China correlated correlation domain ELISA ELISAs enzyme-linked immunosorbent enzyme-linked immunosorbent assay Extracellular inactivated Infection MERS MERS coronavirus MERS-CoV Middle East N-terminal domain neutralization neutralizing antibody NTD occurred Patient pseudovirus RBD RBD ELISA recombinant structural antigens sera Seroconversion significantly Strong syndrome the patient [DOI] 10.1038/emi.2016.114 PMC 바로가기 [Article Type] Original Article
Directional and reoccurring sequence change in zoonotic RNA virus genomes visualized by time-series word countArticle Published on 2016-11-032022-10-29 Journal: Scientific Reports [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] activity addition Analysis change changes in condition diagnostic directional Ebola Ebolavirus Effectiveness Epidemics Factors Genome growth Host hosts human cell influenza A influenza A virus Influenza virus Invasion Long MERS coronavirus Middle East mutate oligonucleotide outbreak primer RNA virus RNA viruses RT-PCR sequence siRNAs subtype Subtypes therapeutic thought virus West zoonotic [DOI] 10.1038/srep36197 PMC 바로가기 [Article Type] Article
Comparison of incubation period distribution of human infections with MERS-CoV in South Korea and Saudi ArabiaArticle Published on 2016-10-242022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] Arabian Peninsula coronavirus determine distribution examined human infection illness onset Incubation period Infection Infectious disease log-linear regression mathematical mean incubation period MERS MERS coronavirus MERS-CoV Middle East outbreak quarantine respiratory Saudi Arabia South Korea the mean Variation [DOI] 10.1038/srep35839 PMC 바로가기 [Article Type] Article
Analytical and Clinical Validation of Six Commercial Middle East Respiratory Syndrome Coronavirus RNA Detection Kits Based on Real-Time Reverse-Transcription PCRArticle Published on 2016-09-242023-06-15 Journal: Annals of laboratory medicine [Category] MERS, [키워드] commercial kits Lower respiratory specimen MERS coronavirus Real-Time Reverse Transcription Polymerase Chain Reaction validation [DOI] 10.3343/alm.2016.36.5.450 PMC 바로가기
Toward Developing a Preventive MERS-CoV Vaccine—Report from a Workshop Organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14–15, 2015Online Report Published on 2016-08-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] Affect animal models Combination coronavirus Developing Dromedary Epidemiology Human international public health International Vaccine Institute MERS MERS coronavirus MERS-CoV Middle East Middle East respiratory syndrome Ministry of Health organizations Pathogenesis platform prevention public health researcher robust Saudi Arabia South Korea Spike protein syndrome therapeutic therapeutic antibodies Transmission Vaccine vaccine candidates Vaccine development Vaccines viruses workshop zoonosis [DOI] 10.3201/eid2208.160229 PMC 바로가기 [Article Type] Online Report
Predicting the international spread of Middle East respiratory syndrome (MERS)Research Article Published on 2016-07-222022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, MERS, [키워드] AIC Airline transportation network Akaike information criterion Analysis analyzed Area assumed AUC calculated coronavirus country covariate distribution effective estimate facilitated help highest importation IMPROVE incidence Infectious disease Intensive International majority MERS MERS coronavirus Middle East Middle East respiratory syndrome Muslim predict Predictive reported Result risk Risk assessment Saudi Arabia sensitivity skewed specificity Spread statistical model Support syndrome Transmissibility Transmission model were used [DOI] 10.1186/s12879-016-1675-z PMC 바로가기 [Article Type] Research Article
Infections in symptomatic travelers returning from the Arabian peninsula to France: A retrospective cross-sectional studyCorrespondence Published on 2016-05-142023-06-14 Journal: Travel medicine and infectious disease [Category] MERS, [키워드] Hajj Influenza MERS coronavirus Pilgrims Travel [DOI] 10.1016/j.tmaid.2016.05.002 PMC 바로가기 [Article Type] Correspondence
Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014Research Published on 2016-05-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, MERS, [키워드] acquisition Contact Coronavirus infections deficiency dialysis Fahd healthcare hospital improvement infection control investigated Jeddah King laboratory-confirmed MERS MERS coronavirus MERS patients MERS-CoV Middle East Middle East respiratory syndrome Coronavirus nosocomial occurred outbreak Outbreaks Patient patients Precaution Prevent respiratory Saudi Arabia syndrome Tertiary Transmission transmitted Treatment vector-borne infections viruses [DOI] 10.3201/eid2205.151797 PMC 바로가기 [Article Type] Research
Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3Original Article Published on 2016-04-202022-10-31 Journal: Emerging Microbes & Infections [Category] Coronavirus, [키워드] Activation antiviral response association C-terminal C-terminal domain characterized chimeric claimed conserved contribute evade ex vivo models expression highly pathogenic Host IFN induce infected patient Infection inhibitory effect innate antiviral response interferon IRF3 IRF3 activation M protein mechanism MERS coronavirus MERS-CoV Middle East mutants N-terminal nuclear Pathogenesis Phosphorylation Protein reduced Regulatory respiratory syndrome coronavirus resulting RIG-I-like receptors SARS-CoV Saudi Arabia Sendai virus suppress suppresse suppressed TRAF3 transmembrane domain Type I IFN type I interferon type I interferons [DOI] 10.1038/emi.2016.33 PMC 바로가기 [Article Type] Original Article
Mortality Risk Factors for Middle East Respiratory Syndrome Outbreak, South Korea, 2015Article Published on 2015-11-012023-06-13 Journal: Emerging Infectious Diseases [Category] MERS, [키워드] disease outbreak infections MERS MERS coronavirus Middle East respiratory syndrome mortality risk factors South Korea viruses [DOI] 10.3201/eid2111.151231 PMC 바로가기