Middle East respiratory syndrome – Page 5 – Communicable Diseases Research

Epidemiology and evolution of Middle East respiratory syndrome coronavirus, 2012–2020

Research Article

Published on 2021-05-082022-10-29
Journal: Infectious Diseases of Poverty [Category] COVID-19, Fulltext, 조류인플루엔자,

Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial

급성 COVID-19 호흡기 질환이 있는 성인을 위한 회복기 혈장(CONCOR-1): 국제, 다기관, 무작위 배정, 공개 시험을 위한 연구 프로토콜

Study Protocol

Published on 2021-05-042022-09-01
Journal: Trials [Category] SARS, 임상, 진단, 치료기술, 치료제,

[키워드] acute COVID-19 acute respiratory syndrome Analysis anti-SARS-CoV-2 antibodies antibodies antibody titres baseline Blood Group CCP Community community acquired community acquired pneumonia CONCOR-1 convalescent plasma coronavirus COVID-19 COVID-19 infection criteria death detect detectable anti-SARS-CoV-2 antibodies detectable anti-SARS-CoV-2 antibody determine Donor donors Ebola Ebola virus Efficacy and safety estimation Evidence exclusion criteria Exploratory analyses global pandemic hospital include inclusion criteria independent Infection Influenza information intensive care interim analysis International Intubated intubation Middle East Middle East respiratory syndrome multicentre NCT04348656 Neutralization assay neutralization assays Non-intubated Novel coronavirus Open-label outcome oxygen Patient patients with SARS-CoV-2 plasma Pneumonia Primary outcome quantified randomization Randomized Randomized controlled trial randomized trial reaction receive receiving recruitment reduce reduction in Relative risk respiratory respiratory complication Respiratory complications Respiratory illness respiratory symptom respiratory symptoms responsible risk risk reduction Sample size SARS-CoV-2 SARS-CoV-2 antibody titre SARS-CoV-2 antibody titres SARS-COV-2 infection SARS-CoV-2 viral load secondary Secondary outcomes Serious Adverse Events Serologically Severe acute respiratory syndrome Standard of care Study protocol supplemental oxygen Support syndrome threshold thresholds titre transfusion reactions Trial two-sided Ventilator-free days Viral viral disease Viral diseases Viral load with COVID-19
[DOI] 10.1186/s13063-021-05235-3 PMC 바로가기 [Article Type] Study Protocol

Emergent Drug and Nutrition Interactions in COVID-19: A Comprehensive Narrative Review

COVID-19의 새로운 약물 및 영양 상호 작용: 종합 내러티브 검토

Review

Published on 2021-05-042022-09-10
Journal: Nutrients [Category] SARS, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Affect Anti-inflammatory Antiviral approved can not caused clinical experience Cold colds Comorbidities Comorbidity Comprehensive coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 death Diseases drug Drug interactions drug-drug interaction Drug-drug interactions drugs Effect evaluated Health Organization ICU include indicated information intensive care intensive care unit Interaction mechanism MERS Middle East Middle East respiratory syndrome narrative New nutrition nutrition interaction nutritional status patients pharmacokinetic pharmacological agent pharmacological agents reported respiratory respiratory tract infection Respiratory tract infections review risk SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 supportive care Treatment treatment for COVID-19 treatment of COVID-19 virus viruses were given WHO World Health Organization worldwide pandemic
[DOI] 10.3390/nu13051550 PMC 바로가기 [Article Type] Review

Clinical characteristics and outcomes of hospitalized COVID-19 patients in a MERS-CoV referral hospital during the peak of the pandemic

대유행이 정점에 달했을 때 MERS-CoV 위탁 병원에 입원한 COVID-19 환자의 임상적 특성 및 결과

Article

Published on 2021-05-012022-09-11
Journal: International Journal of Infectious Diseases [Category] 치료기술,

[키워드] 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age AST biochemical marker Care case sery Characteristics city clinical Clinical characteristics Co-infection Comorbidity coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 creatinine CRP D-dimer death diabete diabetes Dyspnea elevated end-organ damage Fever hospital Hospitalized hospitalized COVID-19 patient hypertension ICU IL-6 individual Infection intensive care intensive care unit King KSUMC less lymphocyte Lymphocyte count lymphopenia male median age MERS MERS-CoV Middle East respiratory syndrome Middle East respiratory syndrome Coronavirus Mortality Most patient Most patients Older Older age outcome pandemic Patient patients required hospitalization polymerase positive real time respiratory syndrome coronavirus reverse transcriptase risk factor Risk factors RT-PCR SARS-CoV-2 Saudi Arabia Seven severe acute respiratory syndrome Coronavirus Severe case severe cases significant increase single-center Symptom symptom duration tested transcriptase troponin Troponin-I university ventilatory support
[DOI] 10.1016/j.ijid.2021.03.058 PMC 바로가기 [Article Type] Article

Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Dispatch

Published on 2021-05-012022-10-31
Journal: Emerging Infectious Diseases [Category] Coronavirus,

Targeting SARS-CoV-2 viral proteases as a therapeutic strategy to treat COVID-19

COVID-19를 치료하기 위한 치료 전략으로 SARS-CoV-2 바이러스 프로테아제 표적화

Review

Published on 2021-05-012022-09-11
Journal: Journal of medical virology [Category] SARS, 치료제,

[키워드] 3 chymotrypsin-like cysteine protease 3CL pro acute respiratory syndrome Amino acid caused chymotrypsin coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus main protease COVID-19 COVID-19 infection CoVs cysteine cysteine protease death Epidemic Infection information MERS Middle East Middle East respiratory syndrome outbreak Papain papain-like cysteine protease. Papain-like protease protease Protein SARS Coronavirus SARS infection SARS-CoV SARS-CoV-2 SARS-CoV-2 viral Severe acute respiratory syndrome similarity Spread Support syndrome targeting the United State Therapeutic molecule therapeutic molecules therapeutic strategy treat treatment strategy United States Viral proteins virus
[DOI] 10.1002/jmv.26814 PMC 바로가기 [Article Type] Review

Comprehensive evaluation of the efficacy and safety of LPV/r drugs in the treatment of SARS and MERS to provide potential treatment options for COVID-19

COVID-19에 대한 잠재적인 치료 옵션을 제공하기 위해 SARS 및 MERS 치료에서 LPV/r 약물의 효능 및 안전성에 대한 종합 평가

Meta-Analysis

Published on 2021-04-302022-09-10
Journal: Aging (Albany NY) [Category] MERS, 치료제,

[키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome addition adverse event adverse events age and sex analyzed Antiviral treatment applied ARDS assessment tool benefit bias risk case-control studies CBM Chest CT China CNKI Cochrane Library Cohort studies Combination comprehensive evaluation conducted control group conversion rate coronavirus disease Coronavirus disease 2019 Coronavirus infections COVID-19 COVID-19 treatment database drug effective Effectiveness Efficacy Efficacy and safety eligible evaluate exhibited Factor incidence Infrastructure literature Lopinavir Lopinavir/ritonavir lower mortality LPV/r MERS Meta-analysis Middle East Middle East respiratory syndrome molecular Newcastle-Ottawa Scale NOS nucleic acid outbreak outcome patients patients with COVID-19 patients with SARS performed potential treatment option prognostic Randomized controlled studies RCT reduced Registration respiratory respiratory distress retrieved Risk assessment Ritonavir SARS Severe acute respiratory syndrome significantly similarities similarity statistically significant Structure syndrome systematic review the Newcastle-Ottawa Scale these viruses Treatment treatment of COVID-19 Trial two group two groups virus clearance viruses was used were used
[DOI] 10.18632/aging.202860 PMC 바로가기 [Article Type] Meta-Analysis

Current COVID-19 treatments: Rapid review of the literature

현재 COVID-19 치료법: 문헌의 신속한 검토

Review

Published on 2021-04-242022-09-10
Journal: Journal of Global Health [Category] MERS, 임상,

[키워드] acute respiratory syndrome Administered benefit case reports clinical clinical benefit clinical trials clinically Combination convalescent plasma coronavirus coronavirus diseases Corticosteroid Corticosteroids COVID-19 COVID-19 treatments current cytokine Cytokine storm database deaths Effect effective eligible English language faster human coronavirus human coronaviruses Hydroxychloroquine Infection inhibitor interferon Lopinavir lopinavir/ ritonavir MERS Middle East Middle East respiratory syndrome monoclonal antibodies monoclonal antibody Mortality not effective observational studies observational study Outbreaks Rapid Recovery time reduced reducing mortality reflected Remdesivir respiratory Result Ritonavir SARS-CoV-2 searched Severe acute respiratory syndrome severe COVID-19 patients Spread Stage systematic review systematic reviews therapeutic effect therapy Treatment trials WHO
[DOI] 10.7189/jogh.11.10003 PMC 바로가기 [Article Type] Review

Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms

장기간의 코로나바이러스 및 코로나바이러스 이후의 건강 합병증: 임상 상태 및 가능한 분자 메커니즘에 대한 최신 검토

Review

Published on 2021-04-182022-09-01
Journal: Viruses [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] abdominal pain Acute myocardial infarction acute respiratory syndrome adverse effects adverse outcome affected anorexia Anxiety Arthritis Ataxia Atherosclerosis Blood coagulation cardiac hypertrophy cardiovascular system Care cerebral hemorrhage characterized clinical condition conducted Confusion constipation convulsions Coronary artery COVID-19 COVID-19 pandemic COVID-19 pathology cytokine Cytokine storm Depression diarrhea disease Diseases Dizziness Effects endothelial fibrosis gastrointestinal hemorrhage Guillain–Barrè syndrome Headaches Health hematological hemiplegia Hemostasis immune system Immune-mediated impaired consciousness imperative Inflammation Inflammatory Kawasaki disease lack lack of appetite Local long-COVID Long-term care loss of taste Lupus mechanism mental health MERS Microvascular thrombosis Middle East Middle East respiratory syndrome molecular mechanism molecular mechanisms multiple organ failures Myocardial myocardial fibrosis nausea nausea/vomiting nervous system outcome Pain pathophysiological pathophysiology pediatric Pneumonia psoriasis Pulmonary embolism pulmonary fibrosis pulmonary system Pulmonary thromboembolism renal system respiratory Respiratory failure review rheumatoid arthritis Severe acute respiratory syndrome Stress stroke Survivors syndrome systemic effects Thromboembolism thrombosis Vascular Vascular damage visual impairment vomiting
[DOI] 10.3390/v13040700 PMC 바로가기 [Article Type] Review

Zoonotic coronavirus epidemics: Severe acute respiratory syndrome, Middle East respiratory syndrome, and coronavirus disease 2019

동물원성 코로나바이러스 전염병: 중증 급성 호흡기 증후군, 중동 호흡기 증후군 및 코로나바이러스 질병 2019

Review

Published on 2021-04-012022-09-11
Journal: Annals of allergy, asthma & immunology : official [Category] SARS, 치료제,

[키워드] acute respiratory syndrome Affect allergy Antiviral Asthma atopy Basic science biologic Biologic therapy caused Clinical characteristics clinical courses clinical manifestation clinical manifestations Clinical outcome coronavirus coronavirus disease Coronavirus disease 2019 coronavirus epidemics Corticosteroids courses COVID-19 COVID-19 infection database deaths deficiencies deficiency disease disease control Effect effective Efficacy Epidemiology fatal disease immunodeficiency immunology immunomodulator immunomodulators Inconclusive Infection inhaled corticosteroid inhaled corticosteroids international public health landscape less maintain MERS Middle East Middle East respiratory syndrome Mild National nucleic acid nucleic acid amplification nucleic acid amplification tests organ organ system outcomes Patient primary antibody Primary Immunodeficiency Severe acute respiratory syndrome syndrome T-cell Therapies therapy Treatment treatment for COVID-19 Virology worldwide pandemic Zoonotic coronavirus
[DOI] 10.1016/j.anai.2020.11.021 PMC 바로가기 [Article Type] Review