Predictors of infection, symptoms development, and mortality in people with SARS-CoV-2 living in retirement nursing homes은퇴 요양원에 거주하는 SARS-CoV-2 감염자의 감염, 증상 발생 및 사망률 예측인자Research Article Published on 2021-03-162022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] age Analysis Angiotensin II blocker chi-square test chronic chronic obstructive pulmonary disease Clinical data collected conducted correlated Cox proportional-hazards model death deaths dependent variable develop died Dyspnea enrolled evaluate evidenced Factor Fever foci Gender heparin high mortality hypokinetic disease increased risk Infection lower mortality risk lower risk male malignancies management Mental Disorders Mortality multivariate analyses Multivariate analysis neurological nursing homes Obstructive obstructive pulmonary disease pandemic Pearson Pearson chi-square test predictor predictors pulmonary disease receptor Retrospective study risk SARS-CoV-2 SARS-COV-2 infection Significant Spread Student’s t-test subjects Swab Symptom Symptoms syndrome Treatment variable was used with infection [DOI] 10.1371/journal.pone.0248009 PMC 바로가기 [Article Type] Research Article
Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study의료 종사자에서 SARS-CoV-2에 대한 항체의 혈청 유병률: 횡단면 연구Public Health Published on 2021-02-122022-09-01 Journal: BMJ Open [Category] Fulltext, MERS, 진단, [키워드] addition Anosmia antibody Bayesian Cohort cohort study confounders Contact contact with COVID-19 COVID-19 diagnosis COVID-19 infection cross-sectional demographic factor Demographic factors determine Diversity Factor Factors Fever functions healthcare healthcare worker Healthcare workers Hispanic ethnicity household identify immune response individual Infection Infectious diseases Los Angele Los Angeles multisite multivariate analyses myalgia myalgias objective outcome participant Patient public health Questionnaires Result robust SARS-CoV-2 SARS-CoV-2 seroprevalence serology testing Seropositivity Seroprevalence setting study population susceptibility Symptom with COVID-19 work functions Workplace [DOI] 10.1136/bmjopen-2020-043584 PMC 바로가기 [Article Type] Public Health
Gender Differences in Concerns About Participating in Cancer Research During the COVID-19 PandemicOriginal Research Article Published on 2021-01-252022-10-31 Journal: Cancer control : journal of the Moffitt Cancer Cen [Category] COVID-19, [키워드] affecting Anxiety anxiety level asked Cancer cancer diagnosis cancer patient clinical trial clinical trials collected concern coronavirus COVID-19 COVID-19 pandemic dataset demographic characteristics determine difference Effect eligible Engagement Future GAD-7 Gender Generalized indicated individuals Interaction less media men men and women Mild multivariate analyses oncology pandemic Patient predicted provided questionnaire reductions in regression analysis reported Research responses SARS-CoV-2 SARS-CoV-2 pandemic t-test Trial women [DOI] 10.1177/1073274821989315 PMC 바로가기 [Article Type] Original Research Article
Peripheral Inflammatory Cytokines and Lymphocyte Subset Features of Deceased COVID-19 Patients사망한 COVID-19 환자의 말초 염증성 사이토카인 및 림프구 하위 집합 특징Research Article Published on 2021-01-222022-09-10 Journal: BioMed Research International [Category] 바이오마커, [키워드] (suppressor T cells Analysis analyzed B cell Cell cell counts cells collected correlated COVID-19 COVID-19 patients cytokine Cytokine storm death death in COVID-19 Deceased decrease feature helper T cells Hyperinflammatory Hyperinflammatory response IL-10 IL-6 IL-8 independent predictor independent predictors indicated induce Inflammatory cytokine Inflammatory cytokines lymphocyte Lymphocyte subset Lymphocyte subsets lymphopenia multivariate multivariate analyses NK cell objective outcome Patient patients peripheral predict remained Result Retrospective study ROC Curve SARS-CoV-2 significantly subset survival survival time survivor Survivors T cell T cells Tongji Hospital with COVID-19 Wuhan Wuhan, China [DOI] 10.1155/2021/9101082 PMC 바로가기 [Article Type] Research Article
Comparison of clinical characteristics among younger and elderly deceased patients with COVID-19: a retrospective studyResearch Paper Published on 2021-01-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] Acute cardiac injury age anorexia Campus chronic cardiac disease Clinical characteristics clinical feature collected Comorbidity Complication confidence interval COVID-19 COVID-19 patient COVID-19 patients Deceased demographic demonstrated described develop Fever interquartile range median age medical records multivariate analyses Odds ratio Patient patients protective factor Retrospective study risk factor SARS-CoV-2 single-center subjects Union Hospital West Wuhan [DOI] 10.18632/aging.202139 PMC 바로가기 [Article Type] Research Paper
Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)코로나바이러스 질병-2019(COVID-19) 입원 환자의 감염성 바이러스 배출 기간 및 주요 결정인자Article Published on 2021-01-112022-09-10 Journal: Nature Communications [Category] MERS, 진단, 치료기술, 치료법, [키워드] 95% confidence interval Analysis coronavirus COVID-19 COVID-19 patient COVID-19 patients Culture determinant determinants disease disease control drop Duration Hospitalized hospitalized patient identify Infection prevention Infectious virus IQR Isolation log median multivariate multivariate analyses non-infectious observé Odds ratio onset of symptom onset of symptoms Patient precautions Prevention and control Quantitative question respiratory respiratory tract respiratory tract sample respiratory tract samples RNA RNA copies SARS-CoV-2 Serological assay serological assays Serum neutralizing antibody titre Translational research Viral viral infection Viral load viral loads viral RNA load virus virus cultures with COVID-19 [DOI] 10.1038/s41467-020-20568-4 PMC 바로가기 [Article Type] Article
Risk factors for mortality and progression to severe COVID-19 disease in the Southeast region in the United States: A report from the SEUS Study GroupOriginal Article Published on 2021-01-112022-10-30 Journal: Infection Control and Hospital Epidemiology [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Admission adults hospitalized advanced age age Analysis cardiovascular disease clinically COVID-19 defined Factor group health system hospital hospital mortality rate Hospitalized ICU admission identify increased risk intensive care laboratory-confirmed Male sex mechanical ventilation Mortality mortality risk multivariate analyses outcomes Patient patients with COVID-19 progression required retrospective cohort risk risk factor SARS-CoV-2 patient severe COVID-19 disease severe disease subsequent The United States United States [DOI] 10.1017/ice.2020.1435 PMC 바로가기 [Article Type] Original Article
An immune-based biomarker signature is associated with mortality in COVID-19 patients면역 기반 바이오마커 시그니처는 COVID-19 환자의 사망률과 관련이 있습니다Research Article Published on 2021-01-112022-09-10 Journal: JCI Insight [Category] 바이오마커, 진단, 치료제, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis analyzed Biomarker biomarker signature Biomarkers Blood CCL2 Cell cells chemokines Clinical outcome contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical CXCL9 Cytokines died Discordance disease disease severity ferritin Hospitalization IFNA2 IL-10 IL-15 IL-1α IL-2 IL-6 immune immunology Inflammatory Inflammatory response Italian patient lactoferrin Mortality multivariable analysis multivariate multivariate analyses outcome Patient predict produced Protein respiratory S100A9 SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity ST2 trajectory transcript level transcriptional type I Type I IFN type I IFNs type II IFN utility with COVID-19 [DOI] 10.1172/jci.insight.144455 PMC 바로가기 [Article Type] Research Article
Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthmaResearch Published on 2021-01-072022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] ACE2 angiotensin Asthma biopsies biopsy Blood body mass index clinical parameter Clusters Cohort Corticosteroid COVID-19 disease enzyme European examined expressed expression expression level functions furin FURIN gene Gender Gene Expression greater host cells inflammasome activation Inflammation inflammatory cells Invasion Level lung male Microarray molecular molecular phenotype morbidity and mortality mRNA expression multivariate analyses neutrophil neutrophilic Neutrophils outcome oxidative phosphorylation Phenotypes protease Proteases Result risk SARS-COV-2 infection serine 2 Severe asthma severity significantly significantly higher significantly increased sputum TMPRSS2 TMPRSS2 level transmembrane Type [DOI] 10.1186/s12931-020-01605-8 PMC 바로가기 [Article Type] Research
Risk Factors, Clinical Characteristics, and Prognosis of Acute Kidney Injury in Hospitalized COVID-19 Patients: A Retrospective Cohort StudyArticle Published on 2021-01-072022-10-29 Journal: Medicines [Category] COVID-19, [키워드] 95% CI Acute kidney injury acute respiratory distress AKI Analysis bacterial co-infection baseline Biomarker Blood urea nitrogen causes characterization clinical Clinical outcome coronavirus COVID-19 Critical diabetes elevated feature ferritin Hospitalized ICU admission increasing age intrinsic kidney Kidney injury Lactate Leukocytosis male Mortality MOST multivariate analyses Non-invasive occurred organ oxygen Patient patients positive pressure ventilation prevalent Record risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection serious complication serum creatinine sodium syndrome therapy transaminitis troponin I urea vasopressors [DOI] 10.3390/medicines8010004 PMC 바로가기 [Article Type] Article