[Hospital inhouse contact tracing-significant impact to patient care during the coronavirus pandemic][병원 내 접촉자 추적 - 코로나바이러스 전염병 동안 환자 치료에 중대한 영향]Article Published on 2021-06-012022-09-11 Journal: Bundesgesundheitsblatt, Gesundheitsforschung, Gesu [Category] SARS, 치료기술, [키워드] addition analysed Ausbruch Cluster Clusters Comprehensive Contact Contact tracing coronavirus database detect District early stage English evaluated Follow-up Germany Health care Health care worker health department hospital house hygiene Infection infection chain infection chains initiated limit Local local infection management material measure negative control Non-COVID-19 oropharyngeal swab outbreak pandemic Pandemic management Patient Patient care PCR positive positive PCR positive PCR result public health quarantine recorded risk of infection RT-PCR RT-PCR throat swabs SARS-CoV‑2 SARS-CoV‑2 symptoms. Spread Symptoms tested tracing virus were recorded [DOI] 10.1007/s00103-021-03330-z PMC 바로가기 [Article Type] Article
Deconvoluting the T Cell Response to SARS-CoV-2: Specificity Versus Chance and Cognate Cross-ReactivitySARS-CoV-2에 대한 T 세포 반응의 해체: 특이성 대 우연 및 동족 교차 반응성Immunology Published on 2021-05-282022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 치료기술, [키워드] Antibody Response Antigen antigens Biomarker chance characteristic clinically Cognate Cold common common cold common cold Coronaviruses coronavirus Course COVID-19 cross-reactive cross-reactivity ELISPOT exposure to False negative Human Immune monitoring immune protection Immunological memory ImmunoSpot individual individuals induce infected individual infected individuals infected with SARS-CoV-2 majority mega peptide pools Mild MOST negative control negative controls peptide peptide pool peptide pools provided respond response SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection serum antibodies serum antibody specific serum T cell T cell affinity T cell memory T cell response T cells Viral viral infections virus [DOI] 10.3389/fimmu.2021.635942 PMC 바로가기 [Article Type] Immunology
Diagnostic Potential of a Luminex-Based Coronavirus Disease 2019 Suspension Immunoassay (COVID-19 SIA) for the Detection of Antibodies against SARS-CoV-2SARS-CoV-2에 대한 항체 검출을 위한 Luminex 기반 코로나바이러스 질병 2019 Suspension Immunoassay(COVID-19 SIA)의 진단 가능성Article Published on 2021-05-262022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Amino acid amino acids antibody Antibody test Antigen antigens assays best blood donor Blood donors Cell Concentration convalescent coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 cross-react detectable detection Diagnostic method enzyme enzyme immunoassay evaluated expressed False positive IgG IgM IgM and IgG immunoassay individual Infants insect cells mammalian negative control other coronaviruses pandemic Patient PCR positive sample Potential Protein Quantitative rapid antibody test respiratory S protein SARS-CoV-2 sensitivity Serologically serology serum sample serum samples Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 specificity suggested Suspension Swedish virus infection was selected with COVID-19 [DOI] 10.3390/v13060993 PMC 바로가기 [Article Type] Article
Association of Metformin with Susceptibility to COVID-19 in People with Type 2 DiabetesClinical Research Articles Published on 2021-05-092022-10-30 Journal: The Journal of Clinical Endocrinology and Metaboli [Category] COVID-19, MERS, [키워드] 95% CI adjusted hazard ratio Analysis back pain cohort study COVID-19 current dataset glycemic control groups IMPROVE include inclusion criteria investigated mechanisms metformin Mortality negative control objective outcome outcome analysis outcomes Patient patients with diabetes performed primary care Result risk factor risk of COVID-19 Safe SARS-COV-2 infection susceptibility Type type 2 diabete Type 2 diabetes mellitus [DOI] 10.1210/clinem/dgab067 PMC 바로가기 [Article Type] Clinical Research Articles
Angiotensin II receptor blocker or angiotensin-converting enzyme inhibitor use and COVID-19-related outcomes among US VeteransResearch Article Published on 2021-04-232022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval 95%CI ACEi ACEIs acute respiratory syndrome all-cause hospitalization all-cause mortality analyses Analysis Angiotensin II angiotensin-converting enzyme inhibitor ARB ARBs association blocker Characteristics coronavirus coronavirus disease covariate adjustment COVID-19 Cox regression death deaths exposure group Follow-up hazard ratio Hospitalization Hospitalized hypertension indication Infection Inpatient Inpatients investigated median medication Mortality negative control outcome Outpatient outpatients Patient Primary outcome randomized trials receptor reduce retrospective cohort study SARS-CoV-2 SARS-COV-2 infection Support treated veteran Weighting [DOI] 10.1371/journal.pone.0248080 PMC 바로가기 [Article Type] Research Article
The course of subjective and objective chemosensory dysfunction in hospitalized patients with COVID-19: a 6-month follow-upRhinology Published on 2021-04-102022-10-31 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, MERS, SARS, [키워드] analogue Anosmia chemosensory Chemosensory dysfunction Cohort control groups coronavirus Course COVID-19 diagnosed dysfunction Effect elevated examined FIVE Follow-up hospitalized patient Hyposmia identification impairment Infection infection with SARS-CoV-2 initial negative control no difference olfactory dysfunction Patient patients performed positive patients Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2-positive patient scale significantly Smell smell training strip suffered Taste Test Visual [DOI] 10.1007/s00405-021-06796-4 PMC 바로가기 [Article Type] Rhinology
Head-to-Head Evaluation of Five Automated SARS-CoV-2 Serology Immunoassays in Various Prevalence SettingsArticle Published on 2021-04-102022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Accuracy Analysis Anti-N anti-S anti-SARS-CoV-2 AUC automated characteristic COVID-19 COVID-19 sera diagnostic DiaSorin displaying electrochemiluminescent immunoassay (ECLIA) Enzyme-linked immunosorbent assay (ELISA) epitope Euroimmun FIVE highest immunoassays negative control Negative predictive value NPV performed population-based cohort Positive predictive value PPV Prevalence Probability reference method ROC Roche S-RBD S1/S2 SARS-CoV-2 screening test selected sensitivity sera serology setting specificity [DOI] 10.3390/jcm10081605 PMC 바로가기 [Article Type] Article
Evaluation of rapid SARS-CoV-2 antigen tests, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 patientsCOVID-19 환자의 일련의 비인두 표본을 사용한 신속한 SARS-CoV-2 항원 검사, AFIAS COVID-19 Ag 및 ichroma COVID-19 Ag의 평가Clinical Trial Published on 2021-04-082022-08-15 Journal: PLoS ONE [Category] MERS, SARS, 임상, 진단, 치료기술, 치료제, [키워드] ( RdRP Accuracy AFIAS COVID-19 Ag analyzed Antigen antigen kinetics collected conjunction COVID-19 COVID-19 patient cycle threshold diagnostic Diagnostic accuracy diagnostic sensitivity Early detection evaluated false negativity ichroma TM COVID-19 Ag investigated kappa value kappa values molecular molecular test Molecular tests nasopharyngeal nasopharyngeal specimen negative control negative controls point-of-care post-symptom onset profile PSO rapid antigen test Rapid antigen tests RAT RATs RdRP SARS-CoV-2 SARS-CoV-2 antigen sensitivity specificity specimen test results TM COVID-19 Ag Viral Viral load were assessed were used [DOI] 10.1371/journal.pone.0249972 PMC 바로가기 [Article Type] Clinical Trial
Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgGArticle Published on 2021-03-312022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Abbott SARS-CoV-2 IgG analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 S1 IgG antibody assays binding convalescent convalescent patient coronavirus correlated COVID-19 COVID-19 pandemic detection diagnostic DiaSorin Elecsy ELISA evaluated highest Humoral response IgG immunoassay investigated LIAISON Live virus negative control neutralization neutralization tests New non-responder nucleocapsid pandemic protection Proteins pseudovirus representing Roche S1 IgG S1/S2 Sample SARS-CoV-2 sensitivity Sensitivity and specificity Serological assay serum sample spike subject tested the antibody response titer [DOI] 10.3390/microorganisms9040733 PMC 바로가기 [Article Type] Article
Prenatal Biochemical and Ultrasound Markers in COVID-19 Pregnant Patients: A Prospective Case-Control StudyArticle Published on 2021-02-262022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] affected alteration Anatomy Anomaly biochemical marker carried chorionic Cohort Control Course COVID-19 COVID-19-related symptom estriol evaluate fetal fetal congenital anomalies fetus first trimester group healthy higher risk Hospital admission incidence investigated Maternal negative control no significant difference noninvasive nuchal translucency plasma protein Pneumonia positive Pregnancy pregnant women prenatal prenatal screening test Prospective prospective observational study SARS-CoV-2 SARS-COV-2 infection screening test Symptom symptomatic SARS-CoV-2 infection tested Ultrasound vertical transmission women [DOI] 10.3390/diagnostics11030398 PMC 바로가기 [Article Type] Article