RETRACTED ARTICLE: Safety and efficacy of favipiravir versus hydroxychloroquine in management of COVID-19: A randomised controlled trial철회된 기사: COVID-19 관리에서 favipiravir 대 hydroxychloroquine의 안전성 및 효능: 무작위 대조 시험Randomized Controlled Trial Published on 2021-03-312022-08-13 Journal: Scientific Reports [Category] 임상, 치료법, 치료제, [키워드] Acute heart failure Acute myocarditis Ain Shams University Hospital Arm Assiut University Hospital average clinical trial Comorbidities comparable COVID-19 demographic characteristics Diagnosis died Drug discovery effective Efficacy enrolled Favipiravir followed by FVP heart failure Heartburn Hydroxychloroquine infected patients management Mild moderate Moderate COVID-19 myocarditis nausea negativity Open-label oral oseltamivir oseltamivir Patient PCR PCR negativity Phase 3 Potential treatment randomised controlled trial randomized-controlled recruited reported Safe Safety SARS-CoV-2 PCR transaminitis Treatment university Viral viral infections [DOI] 10.1038/s41598-021-85227-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Clearing the Fog: Is Hydroxychloroquine Effective in Reducing Coronavirus Disease-2019 Progression? A Randomized Controlled TrialInternal Medicine Published on 2021-03-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] A p-value addition age analyzed assigned Clearing conducted control group Controlled Controlled trial coronavirus disease coronavirus disease-2019 COVID-19 Disease progression Efficacy Emirate enrolled HCQ help Hospitalized IBM Intervention intervention group Mild mild COVID-19 patient mild infection negativity Patient patients PCR PCR negativity polymerase chain progressed RCT reducing Result Science secondary outcome Standard dose Standard of care Statistical Package sustained Treatment viral clearance [DOI] 10.7759/cureus.14186 PMC 바로가기 [Article Type] Internal Medicine
Time Till Viral Clearance of Severe Acute Respiratory Syndrome Coronavirus 2 Is Similar for Asymptomatic and Non-critically Symptomatic IndividualsMedicine Published on 2021-03-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome age and sex Analysis Asymptomatic asypmtomatic Community coronavirus coronavirus 2 COVID-19 implication individual Infection interquartile range negativity public health measure respiratory SARS-CoV-2 SARS-CoV-2-positive participants Spread symptomatic individuals Till time viral clearance viral convergence [DOI] 10.3389/fmed.2021.616927 PMC 바로가기 [Article Type] Medicine
Modeling the Contribution of Male Testosterone Levels to the Duration of Positive COVID Testing among Hospitalized Male COVID-19 PatientsArticle Published on 2021-03-242022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Affect Bacterial Cell COVID COVID-19 COVID-19 patient COVID-19 testing Duration estimates evaluated Evidence explain greater hazard help Hospital admission hospitalized COVID-19 patients immune response Increasing Infection intervals involved Kaplan–Meier Level male male serum testosterone men modeling multivariable Cox regression negativity Oxygen administration pandemic positive COVID-19 Predictive preliminary finding randomized trials Ratio reduced risk factor serum subsequent susceptibility Testing Testosterone the log-rank test total testosterone viral clearance viral infections viral positivity duration [DOI] 10.3390/diagnostics11040581 PMC 바로가기 [Article Type] Article
Effect of age, comorbidity and remission status on outcome of COVID-19 in patients with hematological malignanciesObservational Study Published on 2021-03-012022-10-05 Journal: Blood cells, molecules & diseases [Category] 임상, [키워드] 28-day mortality age anticancer antivirals Chemotherapy Cohort cohorts Comorbidity conducted contributed cough COVID-19 COVID-19 in patient COVID-19 infection death rate disease Effect elderly enrolled Hematological malignancies Hematological malignancy hematology India Infection lymphoid malignancy mild infection moderate MOST multicentre negativity one patient outcome oxygen Patient Remission RT-PCR Secondary objective Seven Severe COVID-19 Infection severe disease Severe infection significantly study period survival Total Treatment [DOI] 10.1016/j.bcmd.2020.102525 PMC 바로가기 [Article Type] Observational Study
Let’s Not Joke about It Too Much! Exposure to COVID-19 Messaging, Attitudes and Protective Behavioral IntentionsArticle Published on 2021-01-252022-10-31 Journal: International journal for equity in health [Category] COVID-19, [키워드] association Attitude Attitudes building concerning COVID-19 develop emotions engage evaluate exposure to humor information Intention Joke Kazakhs likelihood mediation model negative emotion negative emotions negativity Older participant positive predict Protective public communication public health communication Romanian significantly Support Theory of Planned Behavior [DOI] 10.3390/healthcare9020122 PMC 바로가기 [Article Type] Article
Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial중등도에서 중증의 COVID-19(NACOVID) 치료를 위한 nitazoxanide + atazanavir/ritonavir의 효능 및 안전성: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Comparative Study Published on 2021-01-042022-09-10 Journal: Trials [Category] 신약개발, 임상, 치료제, [키워드] 1:1 24 hour 24 hours achievement addition Administered African age allocation anticipated antiretroviral drugs antiviral activity approval Atazanavir atazanavir/ritonavir Blinding Care clinical Clinical improvement Clinical management Comorbidities confirmation Control control group COVID-19 COVID-19 diagnosis COVID-19 infection criteria defined determined by diagnosed Diagnosis discharge dissemination drug Drug administration drugs Efficacy and safety element eliminated enrolment exclusion criteria food Food and Drug Administration Gender group hospital hypersensitivity include inclusion criteria Infectious diseases information initiation of treatment Interaction intervention group Isolation lactating mechanical ventilation medication moderate moderate to severe multicentre Nasopharyngeal swab negativity Nigeria nitazoxanide number objective Ogun once daily Open-label open-label trial Ordinal Scale outcome measure Pan Pan African Clinical Trials Registry participant Patient PCR PCR test Phase 2 physician polymerase chain polymerase chain reaction positive pregnant Proportion of participant protocol quantified randomisation randomised randomised controlled trial receive receiving recruited REDCap Registered registry reported Ritonavir RT-PCR Saliva Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV-2 polymerase chain reaction SARS-CoV-2 viral load secondary care sequence severe COVID-19 specialist Standard Standard of care state Stratification Study protocol supplementary material symptomatic Teaching Temporal the WHO time Treatment Trial Trial registration university Viral Viral load website working [DOI] 10.1186/s13063-020-04987-8 PMC 바로가기 [Article Type] Comparative Study
Clinical characteristics of asymptomatic and symptomatic COVID-19 patients in the Eastern Province of Saudi ArabiaObservational Study Published on 2021-01-012022-10-05 Journal: Journal of infection and public health [Category] SARS, 임상, [키워드] Admission adult COVID-19 patients Asymptomatic asymptomatic patient Characteristics Chest radiograph clinical Clinical characteristics clinical presentation Contact COVID-19 COVID-19 cases COVID-19 infection COVID-19 patient deficiency Diabetes Mellitus epicenter female G6PD Hospitalization hypertension initial intensive care Iraq laboratory data majority median age negative RT-PCR negativity no significant difference p value Patient patients Qatif Radiographic reported required SARS-CoV-2 Saudi Arabia symptomatic the patient [DOI] 10.1016/j.jiph.2020.11.002 PMC 바로가기 [Article Type] Observational Study
Hydroxychloroquine is associated with slower viral clearance in clinical COVID-19 patients with mild to moderate disease하이드록시클로로퀸은 경증에서 중등도 질환을 앓고 있는 임상 COVID-19 환자에서 더 느린 바이러스 제거와 관련이 있습니다.Article Published on 2020-12-242022-09-11 Journal: Medicine [Category] SARS, 치료제, [키워드] 24 hour 24 hours 95% confidence interval adjust antiviral drugs Comorbidities confounder COVID-19 COVID-19 patient Cox proportional hazard defined Efficacy Efficacy and safety followed by hazard ratio HCQ hospitalized patients Hydroxychloroquine Linear regression analysis Mild mild to moderate mild to moderate disease moderate disease Multiple multiple linear regression analysis multivariable nasopharyngeal Nasopharyngeal swab negativity oxygen Oxygen therapy Patient Pneumonia positive Primary outcome randomized clinical trial receive regression analysis RT-PCR assay SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral significantly Symptoms tested Treatment turn use of hydroxychloroquine Viral viral clearance was used [DOI] 10.1097/MD.0000000000023720 PMC 바로가기 [Article Type] Article
Persistent SARS-CoV-2 RNA Positive in Feces but Negative in Breastmilk: A Case Report of COVID-19 in a Breastfeeding PatientMedicine Published on 2020-12-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] breast milk Breastfeeding breastfeeding transmission breastmilk COVID-19 facilitate fecal-oral transmission Fece Gastrointestinal symptom Infectious disease negative negativity oropharyngeal swab pandemic persistent presenting report risk SARS-CoV-2 SARS-CoV-2 RNA serum Transmission transmitted with COVID-19 [DOI] 10.3389/fmed.2020.562700 PMC 바로가기 [Article Type] Medicine