neurons – Page 5 – Communicable Diseases Research

Microglial Implications in SARS-CoV-2 Infection and COVID-19: Lessons From Viral RNA Neurotropism and Possible Relevance to Parkinson’s Disease

Neuroscience

Published on 2021-06-152022-10-31
Journal: Frontiers in Cellular Neuroscience [Category] COVID-19,

[키워드] acute respiratory syndrome addition Brain cells Central nervous system change clearance CNS contribute coronavirus Coronavirus disease 2019 COVID-19 death delirium disease disorders Genetic globe highlight homeostatic Hyposmia immunopathology in viral include individual Infection infections Invasion lesson mechanism Meningitis MERS-CoV microglia microglial Middle East neurodegeneration Neurodegenerative diseases Neuroinvasive neurological Neurological symptom neurons neuropsychiatric disorders neurotropic outbreak pandemic Parkinson’s disease Parkinson’s disease pathogenic pathophysiology plasticity provide re-infected Reinfection Relevance respiratory syndrome coronavirus response responsible rising RNA RNA virus SARS-CoV-2 SARS-COV-2 infection stroke vasculature viral clearance viral infection viral RNA neurotropism
[DOI] 10.3389/fncel.2021.670298 PMC 바로가기 [Article Type] Neuroscience

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

네트워크 의학은 SARS-COV-2/COVID-19 감염을 뇌 미세 혈관 손상 및 치매 유사인지 장애에서 신경 염증에 연결합니다.

Research

Published on 2021-06-092022-09-10
Journal: Alzheimer's Research & Therapy [Category] MERS, SARS, 유전자 메커니즘, 치료기술,

[키워드] addition Alzheimer’s disease Alzheimer’s disease Analysis Antiviral ApoE Biomarker Blood Brain Brain microvasculature brains BSG causal relationship cell types cerebrospinal fluid change Cognitive impairment complications conducted COVID-19 CRISPR CRISPR-Cas9 Defense Dementia elevated Endothelial cell endothelial cells expression expression of SARS-CoV-2 Factor furin Genetic Guidance healthy control healthy controls help Host Human brain IFITM2 IFITM3 IFNAR1 implicated IMPROVE increasingly individual individuals infected with COVID-19 infected with SARS-CoV-2 Infection investigated lead low expression LY6E marker gene Measures mechanism microvascular injury network network medicine Neuroinflammation neurologic neurological manifestation neurological manifestations Neuron neurons overlap pathway Patient patients with COVID-19 Prevalence protein-protein interaction reduced reported responsible Result risk allele RNA-sequencing SARS-CoV-2 SARS-CoV-2 entry factor SARS-CoV-2 entry factors SARS-COV-2 infection Single-cell/nucleus supplementary material the SARS-CoV-2 transcriptomic Transcriptomic analyses transcriptomic profile transcriptomic profiles treatment interventions while
[DOI] 10.1186/s13195-021-00850-3 PMC 바로가기 [Article Type] Research

The olfactory nerve is not a likely route to brain infection in COVID-19: a critical review of data from humans and animal models

Review

Published on 2021-04-262022-10-27
Journal: Acta Neuropathologica [Category]

The olfactory nerve is not a likely route to brain infection in COVID-19: a critical review of data from humans and animal models

Review

Published on 2021-04-262022-10-27
Journal: Acta Neuropathologica [Category] COVID-19, MERS, SARS,

The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys

후각 경로는 SARS-CoV-2가 붉은털 원숭이의 중추 신경계를 침범하는 잠재적인 방법입니다

Article

Published on 2021-04-242022-09-12
Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 진단,

Intercellular viral spread and intracellular transposition of Drosophila gypsy

초파리 집시의 세포간 바이러스 전파 및 세포내 전위

Research Article

Published on 2021-04-222022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] absence acquisition age aging ancestor animals arthropods assembly Author biological processe biological processes Cancer Cell chromosome chromosomes Combination develop disease Drosophila dysfunction element elements envelope gene Evidence exhibit exogenous retrovirus exogenous retroviruses expressed expression feature functional Genome genomes genomic germ line glial cell glial cells host genome implicated Implications incompatible increasingly infectious intercellular Like Long Long Terminal Repeat murine myriad neurodegeneration Neuron neurons occur organism plant plants Protein question raise related diseases Repeat replicate Replication retrotransposon retrotransposons retroviral retrovirus retroviruses similarity somatic cell somatic cells terminal the cell thought tissue transitioned Transmission Viral viral envelope protein viral spread Viral transmission viruses
[DOI] 10.1371/journal.pgen.1009535 PMC 바로가기 [Article Type] Research Article

Cellular mechanisms underlying neurological/neuropsychiatric manifestations of COVID-19

COVID-19의 신경학적/신경정신과적 징후의 기저에 있는 세포 메커니즘

Review

Published on 2021-04-012022-09-12
Journal: Journal of medical virology [Category] Fulltext, MERS, 진단,

Endothelial cells and SARS-CoV-2: An intimate relationship

내피 세포와 SARS-CoV-2: 친밀한 관계

Review

Published on 2021-04-012022-09-12
Journal: Vascular pharmacology [Category] MERS, SARS, 진단,

Hyperparameter Optimization for COVID-19 Pneumonia Diagnosis Based on Chest CT

흉부 CT 기반 코로나19 폐렴 진단을 위한 하이퍼파라미터 최적화

Communication

Published on 2021-03-202022-09-12
Journal: Sensors (Basel, Switzerland) [Category] Coronavirus, 진단,

COVID-19 patient transcriptomic and genomic profiling reveals comorbidity interactions with psychiatric disorders

COVID-19 환자 전사체 및 게놈 프로파일링은 정신 장애와의 동반 질환 상호 작용을 나타냅니다

Article

Published on 2021-03-152022-09-10
Journal: Translational Psychiatry [Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] affected analysed Analysis Anti-inflammatory Bipolar disorder causes co-expression Comorbidity comparison conditions correlated COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients dataset disorder exacerbate gene cluster gene clusters Gene Expression Genome-wide association study genomic GWAS highlight Human behaviour identify immune immune responses immune system in some Infection inflammatory pathway interact Interaction Medical genetics medication mononuclear cell mononuclear cells Neuron neuronal neurons Ontology overlapped pathway Pathways Patient patients PBMC performed Peripheral blood Peripheral blood mononuclear cells Post-traumatic stress disorder profile Psychiatric psychiatric disorder Psychiatric disorders Psychiatric symptom Psychiatric symptoms PTSD reveal SARS-COV-2 infection Schizophrenia Support susceptibilities symptomatic targets transcript Transcriptome transcriptomic Treatment Usage Whole-genome sequence with COVID-19
[DOI] 10.1038/s41398-020-01151-3 PMC 바로가기 [Article Type] Article