Serum Krebs von den Lungen-6 levels are associated with mortality and severity in patients with coronavirus disease 2019혈청 Krebs von den Lungen-6 수준은 2019년 코로나바이러스 질환 환자의 사망률 및 중증도와 관련이 있습니다Article Published on 2021-09-012022-09-11 Journal: Respiratory investigation [Category] MERS, SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome Admission an area analyzed ARDS arterial partial pressure of oxygen cardiovascular center coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cutoff value determine disease disease severity enrolled fraction Hospitalized Japanese Krebs von den Lungen-6 medical record medical records Mortality negative correlation nonsurvivor nonsurvivors on admission outcome oxygen partial pressure Patient patients with COVID-19 Predictive Prognosis progressed reported respiratory Respiratory Center respiratory distress Respiratory distress syndrome sensitivity serum severe disease severity significantly specificity survivor syndrome the disease U/mL [DOI] 10.1016/j.resinv.2021.04.002 PMC 바로가기 [Article Type] Article
Biomarkers of severe COVID-19 pneumonia on admission using data-mining powered by common laboratory blood tests-datasets일반적인 실험실 혈액 검사 데이터 세트로 구동되는 데이터 마이닝을 사용하여 입원 시 중증 COVID-19 폐렴의 바이오마커Article Published on 2021-09-012022-09-11 Journal: Computers in biology and medicine [Category] MERS, SARS, 바이오마커, [키워드] acid-base balance Admission Algorithm analyzed approach artificial intelligence best Biomarkers Blood blood gas Blood gas analyses C-reactive protein clinical laboratory Clinical laboratory techniques clinical outcomes Clustering complex conducted correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia COVID-19 research Data mining dataset datasets Decision tree disease severity epidemiological feature fluctuation form Glucose group hematological Hemogram hidden Hierarchical high risk Hypoxemia Inflammation investigated involved knowledge Laboratory Laboratory tests leukocyte limitation lymphocyte machine machine learning Medical Informatics Applications neutrophil on admission PaO Pearson perceptron performed Pneumonia Precision predict processed Protein Prothrombin time R software severe severe COVID-19 Severe COVID-19 pneumonia severity skill supervised learning therapeutic targets unique variable [DOI] 10.1016/j.compbiomed.2021.104738 PMC 바로가기 [Article Type] Article
Artificial Intelligence Predicts Severity of COVID-19 Based on Correlation of Exaggerated Monocyte Activation, Excessive Organ Damage and Hyperinflammatory Syndrome: A Prospective Clinical Study인공 지능, 과장된 단핵구 활성화, 과도한 장기 손상 및 과염증 증후군의 상관 관계를 기반으로 COVID-19의 심각도 예측: 전향적 임상 연구Immunology Published on 2021-08-272022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단, [키워드] Accuracy Admission Alanine alanine aminotransferase Algorithms ALT Analysis analyzed applied artificial artificial intelligence aspartate Aspartate aminotransferase AST biochemical analyses Biomarker C-reactive protein C-reactive protein (CRP chemokine chemokines clinical COVID-19 COVID-19 patient COVID-19 patients creatinine CT scan CT scans cytokine Cytokines D-dimer damage develop eight fibrinogen forest gamma interferon Glucose healthy control HMGB1 hospitalized COVID-19 patient identify IL-6 intelligence interferon Laboratory Lactate lactate dehydrogenase LDH Logistic regression Lungs Macrophage macrophage derived cytokine management mDC methodology MIG moderate moderate disease monocyte monokine objective on admission parameter predict prediction prediction models predictor Prognostic factor Prognostic factors Prognostic value Prospective provide Random forest reduce mortality Result severe disease severely ill patient severely ill patients severity severity of COVID-19 significantly higher support vector machine the disease the patient [DOI] 10.3389/fimmu.2021.715072 PMC 바로가기 [Article Type] Immunology
D-dimer as a biomarker for assessment of COVID-19 prognosis: D-dimer levels on admission and its role in predicting disease outcome in hospitalized patients with COVID-19COVID-19 예후 평가를위한 바이오 마커로서의 D-Dimer : COVID-19를 가진 입원 환자에서 입원 및 질병 결과를 예측하는 데있어서 D-Dimer 수준.Research Article Published on 2021-08-262022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 바이오마커, [키워드] 95% CI Accuracy adjusted Admission age an area analyzed Biomarker calculate characteristic clinical confirmed COVID-19 case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 patients Cox proportional hazard Cox proportional hazards regression analysis Cutoff cutoff value D-dimer D-dimer level D-dimer value determine died dimer disease Elevation fibrinogen Fibrinogen Equivalent Unit hazard ratio hospital Hospital mortality Hospital stay hospitalized patient hospitals in Kathmandu immunofluorescence assay laboratory parameter Laboratory parameters Mortality on admission outcome Patient patients with COVID-19 poor prognosis predict Predictive Predictive value Prognosis receiver operating characteristic receiver operating characteristic curve recorded regression analysis reported respiratory Respiratory illness Result ROC Curve sensitivity specificity surviving patient surviving patients thrombotic disorders two group two groups was measured was used with COVID-19 [DOI] 10.1371/journal.pone.0256744 PMC 바로가기 [Article Type] Research Article
The first newborn patient with SARS-CoV-2 variant B.1.1.7 identified in Viet Nam: treatment and care practicesSARS-COV-2 변이체를 가진 최초의 신생아 B.1.1.7 베트남에서 확인 : 치료 및 치료 관행Case Reports Published on 2021-08-162022-09-10 Journal: Western Pacific Surveillance and Response Journal [Category] MERS, SARS, 변종, 치료기술, [키워드] Admission Adult patients B.1.1.7 B.1.1.7 variant breastmilk Care Child Clinical characteristics clinical feature Clinical features clinical symptom Contact tracing cough country COVID-19 described diarrhoea digestive discharge during treatment equipment Great Britain hand sanitizer Hospitalization infected with SARS-CoV-2 information Ireland Medical mask medical masks mother mother and child Newborn no symptom no symptoms on admission Patient patient with SARS-CoV-2 patients Personal protective equipment preventive measure preventive measures productive cough provided receive runny nose SARS-CoV-2 SARS-CoV-2 variant Spread Symptom Symptoms tested the patient these symptoms Treatment United Kingdom variant vomiting was used while [DOI] 10.5365/wpsar.2021.12.2.008 PMC 바로가기 [Article Type] Case Reports
Delayed neutralizing antibody response in the acute phase correlates with severe progression of COVID-19급성기에서 지연된 중화 항체 반응은 COVID-19의 심각한 진행과 관련이 있습니다.Article Published on 2021-08-162022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adaptive immunity Admission analyzed antibodies chemiluminescence collected coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 patient Critical disease Delayed different time points disease disease severity Hospitalization moderate moderate disease NAb nAb response NAbs neutralization neutralization activity neutralization test Neutralizing activity neutralizing antibody Neutralizing antibody response on admission pathology Patient patients patients with moderate progression Pseudotyped virus reduction respiratory SARS-CoV-2 SARS-CoV-2 pseudotyped virus serum serum sample severe acute respiratory syndrome Coronavirus significantly higher symptom onset symptomatic viral infection were measured [DOI] 10.1038/s41598-021-96143-8 PMC 바로가기 [Article Type] Article
Risk factors for prolonged virus shedding of respiratory tract and fecal in adults with severe acute respiratory syndrome coronavirus‐2 infection중증급성호흡기증후군 코로나바이러스-2 감염 성인의 호흡기 및 대변의 장기간 바이러스 배출 위험인자Research Article Published on 2021-08-132022-09-10 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, SARS, 치료제, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission age and gender Analysis Antiviral Antiviral treatment BMI carried CD4+ T cell Chloroquine Chloroquine phosphate Combination coronavirus COVID‐19 COVID‐19 patient COVID‐19 determine during treatment effective enrolled Factor Factors fecal immunomodulatory independent risk factor independent risk factors Infection initial longitudinal study Lopinavir Lopinavir/ritonavir mechanism multivariable logistic regression Multivariable logistic regression analysis multivariate logistic regression multivariate logistic regression analysis NK cell NK cells obesity on admission pattern phosphate positive potential risk prolonged viral shedding rectal swab regimen respiratory respiratory tract Result retrospective risk factor Ritonavir RNA SARS‐CoV‐2 SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus significantly Stool suggested T cell Treatment Viral viral shedding virus virus clearance [DOI] 10.1002/jcla.23923 PMC 바로가기 [Article Type] Research Article
Elevated Plasma Fibrinogen Is Associated With Excessive Inflammation and Disease Severity in COVID-19 Patients증가된 혈장 피브리노겐은 COVID-19 환자의 과도한 염증 및 질병 중증도와 관련이 있습니다Cellular and Infection Microbiology Published on 2021-08-032022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료기술, [키워드] Admission analyzed Biomarker cardiac injury cardiovascular disease center characterized Coagulation Coagulopathy coronavirus coronavirus disease Coronavirus disease 2019 (COVID-19) Coronavirus disease-19 correlations COVID-19 COVID-19 patient COVID-19 patients Cutoff disease disease severity elevated excessive inflammation fibrinogen fibrinogen level Fibrinogen levels ICU ICU admission Inflammation Inflammatory marker inflammatory markers Inflammatory response Injury intensive care intensive care unit investigated laboratory characteristics laboratory parameter Laboratory parameters on admission Patient patients predict Result sensitivity Sensitivity and specificity severe disease significantly troponin I university [DOI] 10.3389/fcimb.2021.734005 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Predictors of venous thromboembolism in patients with COVID-19 in an underserved urban population: A single tertiary center experience소외된 도시 인구에서 COVID-19 환자의 정맥 혈전 색전증 예측자: 단일 3차 센터 경험Article Published on 2021-08-012022-09-11 Journal: The clinical respiratory journal [Category] MERS, SARS, 바이오마커, [키워드] addition Admission analyzed AUC center characteristic Clinical characteristics collected COVID-19 COVID-19 patient Cutoff D-dimer D-dimer level D-dimer levels death deficiency demographic demographic and clinical characteristics Factor Final Hospitalized intubation lack marker multivariable logistic regression Novel coronavirus obstructive sleep apnea on admission Patient patient data patients with COVID-19 peak peak D-dimer Philadelphia predictors Prophylaxis Prospective Study receiver operating characteristic reported Retrospective analysis ROC SARS-COV-2 infection Sensitivity and specificity significantly higher significantly increased sleep apnea systemic inflammation T-tests Thromboembolism underlie vasopressor requirement vasopressor requirements Venous Thromboembolism VTE VTE risk [DOI] 10.1111/crj.13377 PMC 바로가기 [Article Type] Article
Prognostic significance of cardiac injury in COVID-19 patients with and without coronary artery disease관상동맥 질환이 있거나 없는 COVID-19 환자에서 심장 손상의 예후적 의미Multicenter Study Published on 2021-08-012022-09-11 Journal: Coronary artery disease [Category] 바이오마커, [키워드] 95% CI 95% confidence interval Acute kidney injury acute respiratory distress acute respiratory distress syndrome Admission age Analysis CAD cardiac injury Characteristics clinical Clinical characteristics Clinical outcome collected consecutive patient consecutive patients Coronary artery Coronary artery disease COVID-19 COVID-19 patient COVID-19 patients CRP levels Diagnosis disease electronic medical records elevated Frequency high mortality hospitalized patient ICU independent predictor independent predictors Injury Laboratory laboratory findings male median age medical records Mortality mortality rate mortality risk Multivariate analysis on admission outcome Patient patients with COVID-19 predicted prognostic required respiratory distress Respiratory distress syndrome Retrospective study risk factor Risk factors subgroup analysis syndrome the median treated with COVID-19 [DOI] 10.1097/MCA.0000000000000914 PMC 바로가기 [Article Type] Multicenter Study