The Impact of the Covid-19 Pandemic and the Lockdown on the Health and Living Conditions of Undocumented Migrants and Migrants Undergoing Legal Status RegularizationPublic Health Published on 2020-12-162022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] accumulated affected asked avoidance Care cohort study condition conducted consequence COVID-19 COVID-19 crisis cross-sectional cumulative domain domains group Health high risk highlight Impact lack less living conditions lockdown material migrant overlapped participant poor mental health Prevalence questionnaire respond risk seeking status Support Switzerland undergo undocumented was selected while [DOI] 10.3389/fpubh.2020.596887 PMC 바로가기 [Article Type] Public Health
SARS-CoV-2 receptor networks in diabetic and COVID-19-associated kidney disease당뇨병 및 COVID-19 관련 신장 질환의 SARS-CoV-2 수용체 네트워크Article Published on 2020-12-012022-09-11 Journal: Kidney international [Category] SARS, 유전자 메커니즘, [키워드] ACE ACE inhibitors ACE2 ACE2 expression ACE2 receptor acute kidney Acute kidney injury aldosterone Alter angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Bayesian biopsy Cell cellular COVID-19 dataset diabetes Diabetic diabetic kidney diabetic nephropathy Donor endomembrane epithelial epithelial cell epithelial cells expression expression pattern expression patterns healthy hospitalized patient host cells immune activation In situ hybridization infected cells Infection inhibitor Integrative analysis investigated kidney kidney damage Kidney disease kidneys living donors mechanism medication medications molecular molecular networks morbidity morbidity and mortality overlapped Patient patients with diabete proximal proximal tubules Renin renin-angiotensin-aldosterone system Research risk stratification RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2-infected cells scRNAseq scRNAseq. susceptibility the SARS-CoV-2 Therapeutic strategies therapeutic strategy Urine Viral viral entry with COVID-19 [DOI] 10.1016/j.kint.2020.09.015 PMC 바로가기 [Article Type] Article
Attitudes and Beliefs on Influenza Vaccination during the COVID-19 Pandemic: Results from a Representative Italian SurveyArticle Published on 2020-11-302022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome analyzed Attitude Attitudes belief Community coronavirus coronavirus disease country Coverage COVID-19 COVID-19 pandemic cross-sectional survey effective First wave General population identify individuals Influenza influenza vaccines information Italian Italy less mandatory Misconception overlapped pandemic participant Practitioner receiving response Result SARS-CoV-2 Seasonal influenza spread to subject survey targeted intervention vaccination Vaccine Vaccine hesitancy [DOI] 10.3390/vaccines8040711 PMC 바로가기 [Article Type] Article
An Immunoinformatics Study to Predict Epitopes in the Envelope Protein of SARS-CoV-2Research Article Published on 2020-11-252022-10-31 Journal: The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien des Maladies Infectieuses et de la Microbiologie Médicale [Category] COVID-19, [키워드] affected Analysis analyzed B-cell epitope binding energy Bioinformatics analysis carried caused Cell-mediated immune responses complementary computational method coronavirus Coverage COVID-19 CTL CTL epitope disease docked elicit envelope envelope protein epitope evaluated HLA allele HTL humoral IEDB Immune Epitope Database immune system in vitro in vivo NCBI database overlapped peptide peptide-based vaccine predict predicted retrieved SARS-CoV-2 sequence suggested Support T-cell epitopes Vaccine vaccine for COVID-19 virus was determined was performed [DOI] 10.1155/2020/7079356 PMC 바로가기 [Article Type] Research Article
Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort studyCOVID-19에 대한 수정 가능 및 수정 불가능 위험 요인 및 인플루엔자 및 폐렴 위험 요인과의 비교: UK Biobank 전향 코호트 연구 결과Epidemiology Published on 2020-11-192022-09-10 Journal: BMJ Open [Category] Fulltext, SARS, 바이오마커, [키워드] association blood pressure body mass body mass index Cardiology cholesterol clinical risk factor Confirmed Confirmed COVID-19 infection COVID-19 COVID-19 infection cystatin C diabetes & endocrinology Epidemiology expiratory forced expiratory volume General population Haemoglobin HDL help high risk high-density High-density lipoprotein hypertension incident increase in index Influenza influenza and pneumonia less lower risk Male sex medication Modification multivariable objective outcome measure outcomes overlapped participant Participants physical physical fitness Pneumonia Poisson regression population study positive primary care prospective cohort study reduce Result risk factor Risk factors risk of COVID-19 SARS-CoV-2 test setting shielding smoking social distancing Socioeconomic deprivation UK biobank variable Volume was used [DOI] 10.1136/bmjopen-2020-040402 PMC 바로가기 [Article Type] Epidemiology
Target-Centered Drug Repurposing Predictions of Human Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Protease Serine Subtype 2 (TMPRSS2) Interacting Approved Drugs for Coronavirus Disease 2019 (COVID-19) Treatment through a Drug-Target Interaction Deep Learning Model인간 안지오텐신 전환 효소 2(ACE2) 및 막관통 프로테아제 세린 아형 2(TMPRSS2) 상호 작용에 대한 표적 중심 약물 용도 변경 예측Article Published on 2020-11-182022-08-31 Journal: Viruses [Category] SARS, 신약개발, [키워드] ACE ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 approval approved drug AT1R candidate clinically Control coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 daclatasvir deep deep learning drug Drug repurposing drug-target drugs enalaprilat eprosartan FDA FDA approved drug food gene expression profile HCV Host host cell Human inhibit inhibitor inhibitory potency Interaction learning less lisuride Model molecule Neuropsychiatric ombitasvir overcome overlapped paritaprevir portal predict predicted prediction protease receptor Remdesivir Replication reported repurposing respiratory SARS-CoV-2 SARS-CoV-2 replication SARS-CoV-2 spike Serine serine 2 severe acute respiratory syndrome Coronavirus subtype target TMPRSS2 TMPRSS2 inhibitors transmembrane transmembrane protease serine 2 Treatment Viral viral entry virus [DOI] 10.3390/v12111325 PMC 바로가기 [Article Type] Article
COVID-19 and maintenance hemodialysis: a systematic scoping review of practice guidelinesResearch Article Published on 2020-11-102022-10-28 Journal: BMC Nephrology [Category] COVID-19, SARS, [키워드] Abstract article articles Care case sery Characteristics checklist clinical care conducted COVID-19 Descriptive analysis dialysis disease End English language ESRD Hemodialysis identify impacted inclusion criteria Infection Italy management medical services MOST overlapped pandemic Patient performed recommendation recommendations renal Research Result RRT SARS-CoV-2 screened single-center Stage The United States Topic unique Web of Science while [DOI] 10.1186/s12882-020-02143-7 PMC 바로가기 [Article Type] Research Article
Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes인간 폐의 단일 세포 다중체 프로파일링은 SARS-CoV2 숙주 유전자의 세포 유형 특이적 및 연령 동적 제어를 보여줍니다Research Article Published on 2020-11-092022-09-10 Journal: eLife [Category] SARS, 변종, [키워드] age alveolar alveolar cell alveolar cells association cell types cells chromatin cis-regulatory elements COVID-19 dataset distal Donor donors element expressed facilitate focus functional Gene regulation Host host gene Human human lung human sequence variants immune implicated Interpretation locus lung lung cell Lung diseases Lungs mapped nuclei overlapped profile putative target genes receptor ACE2 Regulatory respiratory Respiratory failure reveal risk risk loci SARS-CoV-2 SARS-CoV-2 receptor SARS-CoV2 single cell RNA/ATAC-seq SLC6A20 Target genes the SARS-CoV-2 TMPRSS2 traits Transcriptome transcriptomes variant with COVID-19 [DOI] 10.7554/eLife.62522 PMC 바로가기 [Article Type] Research Article
Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent populationResearch Article Published on 2020-09-172022-10-31 Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS, [키워드] antibody B-cell blocked caused composed convalescent convalescent sera COVID-19 Diagnosis Dilution dominant epitope Efficacy elicit elicited epitope FIVE indicated Interaction linear epitope membrane mortalities neutralization activity Neutralizing neutralizing antibody Non-COVID-19 overlapped pandemic peptide performed Proteins SARS-CoV-2 SARS-CoV-2 vaccine sera specific antigen the vaccine Vaccine vaccine candidate viral infection [DOI] 10.1080/22221751.2020.1815591 PMC 바로가기 [Article Type] Research Article
Vaccine Design from the Ensemble of Surface Glycoprotein Epitopes of SARS-CoV-2: An Immunoinformatics ApproachArticle Published on 2020-07-282022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome allergenicity antibody production antigenicity B-cell binding energy booster dose complex coronavirus coronavirus disease COVID-19 docked downstream elicit Epitopes FIVE IEDB immune response immune system induce Interaction molecular docking Multi-epitope vaccine multi-epitopes overlapped pathway peptide-based physiochemical properties Pneumonia predicted pro-inflammatory cytokine RMSF SARS-CoV-2 selected surface T-cell epitope the vaccine TLR TLR4 TLR7 TLR8 Vaccine vaccine candidate vaccine construct virus was done [DOI] 10.3390/vaccines8030423 PMC 바로가기 [Article Type] Article