RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical ImpactN501Y, 69-70del, K417N 및 E484K SARS-CoV-2 돌연변이의 신속한 검출을 위한 RT-qPCR 분석: 임상적 영향이 있는 변이체 식별을 위한 스크리닝 전략Cellular and Infection Microbiology Published on 2021-05-202022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 변종, 치료기술, 치료제, [키워드] Amplicon amplicons applied assays clinical clinical impact clinical sample clinical samples COVID-19 pandemic COVID-19 patient detect detection E484K E484K mutation Effects epidemiological epidemiological surveillance gene mutation Impact individual K417N molecular molecular screening Mutation N501Y nine P.2 P.2 variant P.2 variant detection pathogenic Primers probe provide Quantitative Rapid Result reverse transcription PCR RT-qPCR RT-qPCR assay Sanger sequencing SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 mutation screening SARS-CoV-2 mutations Screening Sequencing several variants specificity Strategy Surveillance targeting the SARS-CoV-2 variant [DOI] 10.3389/fcimb.2021.672562 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
A Potential SARS-CoV-2 Variant of Interest (VOI) Harboring Mutation E484K in the Spike Protein Was Identified within Lineage B.1.1.33 Circulating in Brazil스파이크 단백질의 돌연변이 E484K를 포함하는 잠재적인 SARS-CoV-2 관심 변이체(VOI)는 브라질에서 순환하는 계보 B.1.1.33 내에서 확인되었습니다Communication Published on 2021-04-212022-09-10 Journal: Viruses [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.1.28 B.1.1.33 Brazil concern coronavirus described E484K Epidemic epidemiologically Genomic epidemiology Identified interest Lineage lineages multiple mutation multiple mutations Mutation N.9 N501Y new SARS-CoV-2 Non-synonymous North Nsp3 P.1 P.2 Potential Protein Receptor-binding domain regions respiratory S protein SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus South Spread the receptor-binding domain the S protein the Spike variant variant of interest VoC [DOI] 10.3390/v13050724 PMC 바로가기 [Article Type] Communication
Genomic Characterization of a Novel SARS-CoV-2 Lineage from Rio de Janeiro, BrazilLetter to the Editor Published on 2021-03-012022-10-30 Journal: Journal of Virology [Category] COVID-19, [키워드] Brazil characterization COVID-19 E484K Genomic surveillance novel P.2 Rio de Janeiro SARS-CoV-2 [DOI] 10.1128/JVI.00119-21 PMC 바로가기 [Article Type] Letter to the Editor