A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?Covid-19 Malady의 임상 및 기계적 병리 생리 학적 측면에 대한 포괄적 인 검토 : 우리는 얼마나 멀리 왔습니까?Review Published on 2021-06-072022-09-10 Journal: Virology Journal [Category] MERS, 치료제, [키워드] ACE2 receptors affecting analyzed approved articles Case report case reports Case series clinical presentation comorbid disease comorbid diseases Comorbidities Comorbidity contributed coronavirus coronavirus disease COVID-19 current cytokine cytokine production damage determine disease manifestation disease severity Effect Entry mechanism host cell host cells immune response include Inflammation irreversible damage lead long term Manifestations mechanism Mortality observational studies organ damage organ system organ systems outbreak pandemic pathology pathophysiologic pathophysiological Pathways patients penetration Prevalence recorded Research retrieved reveal short term Signs and symptoms SPSS Symptoms systemic inflammation Treatment underlying disease Vaccine Viral Viral proteins [DOI] 10.1186/s12985-021-01578-0 PMC 바로가기 [Article Type] Review
SARS‐CoV‐2 infection and paediatric endocrine disorders: Risks and management considerationsReview Published on 2021-06-032022-10-31 Journal: Endocrinology, Diabetes & Metabolism [Category] COVID-19, MERS, [키워드] caused children Complication content coronavirus COVID‐19 COVID‐19 develop disease disorder disorders Effect Endocrine Endocrinopathy Glucose Guidance highlight humans Interaction management metabolism mineral metabolism outcome paediatric endocrine disorders pathophysiologic Patient Pituitary provide recommendation Research response risk risk factor SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 virus SARS‐CoV‐2 underlying disorder while [DOI] 10.1002/edm2.262 PMC 바로가기 [Article Type] Review
Central and peripheral nervous system involvement by COVID-19: a systematic review of the pathophysiology, clinical manifestations, neuropathology, neuroimaging, electrophysiology, and cerebrospinal fluid findingsResearch Article Published on 2021-06-022022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] Affect Analysis articles Brain Central and peripheral nervous system cerebrospinal fluid Cerebrospinal fluid findings Characteristics clinical manifestations Collaborative effort condition conducted COVID-19 described Electrophysiology ENhance Evidence excluded feature Frequency generate knowledge measure Measures mechanism mortality rate nervous system Neuroimaging neurological neurological impairment Neurological involvement neurological manifestation Neuropathology pathophysiologic pathophysiological mechanism pathophysiology Patient patients patients with COVID-19 Prevalence provided Registered Registration reported Result SARS-CoV-2 SARS-COV-2 infection structures subjects systematic review therapeutic translational [DOI] 10.1186/s12879-021-06185-6 PMC 바로가기 [Article Type] Research Article
Association of Circulating Sex Hormones With Inflammation and Disease Severity in Patients With COVID-19Research Published on 2021-05-252022-10-29 Journal: JAMA Network Open [Category] COVID-19, SARS, [키워드] 95% CI Admission age association C-reactive protein CD14 CD16 cellular signaling pathways circulating classical clinical trial cohort study collected Concentration concentrations conducted consecutive patient contribute COVID-19 COVID-19 illness diagnosed disease disease severity enrichment analysis estradiol exposure finding growth factor hepatocyte growth factor hormone hormone concentration Hospitalization Hospitalized Hypothesis IGF-1 Importance Inflammation Inflammatory cytokine intensive care interferon male measure median men monocyte mononuclear cell nasopharyngeal swabs objective outcome participant pathophysiologic Patient patients with COVID-19 Point predisposition prospective cohort study Protein receptor regulated Relevance remained required Result risk factor RNA sequencing serum serum sample setting severe COVID-19 severe COVID-19 illness severity Sex sex hormone Signaling signaling pathway single-center Testosterone the patient Treatment upregulated upregulation was performed were measured with COVID-19 women [DOI] 10.1001/jamanetworkopen.2021.11398 PMC 바로가기 [Article Type] Research
Obesity as a Risk Factor for Severe Illness From COVID-19 in the Pediatric PopulationPediatrics Published on 2021-05-032022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Adults age association Case report children clinical care Clinical data Clinical outcome coronavirus coronavirus disease COVID-19 COVID-19 infection Critical disease determine disease course disease severity Factor Factors illness increased risk Medical conditions morbidity and mortality obesity outbreak pathophysiologic pediatric Population Recognition risk risk factor Risk factors SARS-CoV-2 severe COVID-19 disease Treatment strategies [DOI] 10.7759/cureus.14825 PMC 바로가기 [Article Type] Pediatrics
Elevated Liver Biochemistries in Hospitalized Chinese Patients With Severe COVID-19: Systematic Review and Meta-analysis중증 COVID-19로 입원한 중국 환자의 간 생화학 증가: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-04-012022-09-11 Journal: Hepatology (Baltimore, Md.) [Category] MERS, SARS, 바이오마커, [키워드] 95% CI 95% confidence interval Alanine alanine aminotransferase albumin aspartate Aspartate aminotransferase association Bilirubin Cerebrovascular disease Chinese Chinese patient chronic obstructive chronic obstructive pulmonary disease Clinical significance Comorbidities Coronary artery Coronary artery disease coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 infections creatinine creatinine kinase Critically ill elevated elevated lactate dehydrogenase Elevation elevations Hospitalized Infection Lactate lactate dehydrogenase LDH Leukocytosis liver lymphopenia manifestation mean difference mechanism Meta-analysis mild case mild cases neutrophilia obstructive pulmonary disease pathophysiologic Patient Prevalence prevalent Prospective Study prothrombin Prothrombin time pulmonary disease reported review Severe case statistical significance systematic review total bilirubin with COVID-19 [DOI] 10.1002/hep.31472 PMC 바로가기 [Article Type] Meta-Analysis
Syncope Associated with Sinus Nodal Dysfunction in a COVID-19 Patient: A Case Report and Review of the LiteratureArticle Published on 2021-02-182022-10-27 Journal: American journal of medical case reports [Category] COVID-19, [키워드] acute respiratory syndrome arrhythmia bradycardic cardiac complication cardiovascular disease cardiovascular dysfunction caused Clinical characteristics complications of COVID-19 coronary syndrome Coronavirus-2 COVID-19 COVID-19 infection COVID-19 patient de novo disease dysfunction Evidence heart failure include literature management mechanism myocarditis pathophysiologic Patient positive SARS-CoV-2 PCR report review SARS-CoV-2 Sinus sinus node sinus node dysfunction (SND) Syncope with COVID-19 [DOI] 10.12691/ajmcr-9-4-15 PMC 바로가기 [Article Type] Article
SARS-CoV-2 tropism: what urologists need to knowReview Published on 2021-02-012022-10-27 Journal: African Journal of Urology [Category] COVID-19, [키워드] affected affecting Consequences COVID COVID-19 Diseases genitourinary tract highlight Infection Initially involved organ organotropism pandemic pathophysiologic reducing SARS-CoV-2 SARS-CoV2 similarity the SARS-CoV-2 virus thought transmitted Urinary tract Urology viral infection [DOI] 10.1186/s12301-021-00126-0 PMC 바로가기 [Article Type] Review
Low level of Vitamin C and dysregulation of Vitamin C transporter might be involved in the severity of COVID-19 InfectionCommentary Published on 2021-02-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] administration aging antioxidant approved drug booster conditions conducted coronavirus coronavirus 2 COVID-19 disease drug drugs dysregulation effective Efficacy effort expression FDA food humans immune immune response Immunity individual information inherent inherent property Intervention involved lack life-threatening manuscript pathophysiologic profiles provide Research respiratory SARS-CoV-2 Scientific community severity of COVID-19 Treatment treatment for COVID-19 viral infection virus Vitamin Vitamin C [DOI] 10.14336/AD.2020.0918 PMC 바로가기 [Article Type] Commentary
Impact of COVID-19 on hospital admission of acute stroke patients in BangladeshResearch Article Published on 2021-01-132022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] Admission average changes in COVID-19 COVID-19 infections COVID-19 pandemic determine dropped expected female Frequency Hospital admission Hospitalization ICH Impact Injury Intracerebral hemorrhage investigated male management measure mechanism nasal swab neurologic neuroscience Older pandemic pathophysiologic Patient Poisson regression Poisson regression model positive reduction reduction in reductions in reperfusion Result Retrospective analysis RT-PCR SARS CoV-2 significantly statistically significant stroke study period subarachnoid hemorrhage the mean the patient Treatment venous were used [DOI] 10.1371/journal.pone.0240385 PMC 바로가기 [Article Type] Research Article