A Phase II Safety and Efficacy Study on Prognosis of Moderate Pneumonia in Coronavirus Disease 2019 Patients With Regular Intravenous Immunoglobulin Therapy정기적인 정맥 면역글로불린 요법을 받는 코로나바이러스 질병 2019 환자의 중등도 폐렴 예후에 대한 2상 안전성 및 효능 연구Clinical Trial Published on 2021-05-202022-09-11 Journal: The Journal of Infectious Diseases [Category] SARS, 임상, 진단, 치료제, [키워드] 1:1 adjuvant adverse event adverse events antiviral drug antiviral drugs benefit body temperature both groups Chain Reaction conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients demonstrated died Diseases Duration Efficacy eligible patient evaluate except for group Hospital stay Immunoglobulin immunoglobulin therapy in both group Intravenous immunoglobulin IVIG mechanical ventilation median time Mild mild to moderate moderate multicenter negativity normalization not significantly different on mechanical ventilation Open-label oxygen oxygen saturation Patient percentage percentages phase Pneumonia polymerase chain polymerase chain reaction Randomized randomized study receive Regular Safe Safety SARS-CoV-2 significantly shorter Standard of care therapeutic benefits Treatment [DOI] 10.1093/infdis/jiab098 PMC 바로가기 [Article Type] Clinical Trial
Correlation of Low Levels of α -1 Antitrypsin and Elevation of Neutrophil to Lymphocyte Ratio with Higher Mortality in Severe COVID-19 Patients중증 COVID-19 환자에서 낮은 수준의 α-1 항트립신과 호중구 대 림프구 비율 상승과 사망률의 상관관계Observational Study Published on 2021-04-282022-09-10 Journal: Mediators of Inflammation [Category] MERS, SARS, 유전자 메커니즘, 임상, [키워드] accounted Admission alterations antitrypsin arterial oxygen saturation blood count blood sugar C-reactive protein CBC Chain Reaction cohort study Comorbidities complete blood count COVID-19 COVID-19 illness COVID-19 patient CRP CRP level CRP values dysregulated immune response dysregulation Elevation erythrocyte sedimentation erythrocyte sedimentation rate ESR etiology explanation form Glutamate groups Hospitalization hospitalized patient hospitalized patients hyperinflammation immune dysregulation immune response immunomodulatory effect individual Individual differences inflammation response involved Level lymphocyte marker mechanism mortality rate MOST neutrophil NLR not significantly different O2sat Observational cohort study Oxaloacetate oxygen oxygen saturation patients PCR percentage percentages plasma protein polymerase chain polymerase chain reaction positive COVID-19 Prevalence pyruvate random Ratio RBC Result retrospective sedimentation rate serum Serum level severe COVID-19 severe COVID-19 illness severe COVID-19 patient severe COVID-19 patients severe forms of COVID-19 severe symptoms severity SGOT SGPT sugar the patient troponin troponin level troponin levels with COVID-19 [DOI] 10.1155/2021/5555619 PMC 바로가기 [Article Type] Observational Study
Predictors of willingness to get a COVID-19 vaccine in the U.SResearch Article Published on 2021-04-122022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] age American black children COVID-19 vaccine distribution effort English group Health Hispanic household implementation increased risk less lower risk medical condition MOST National Novel coronavirus obesity Older participant percentages Population Probability Public public health public health communication question recruited reported Result SARS-CoV-2 vaccine Spanish the vaccine vaccinate Vaccine Vaccine hesitancy white [DOI] 10.1186/s12879-021-06023-9 PMC 바로가기 [Article Type] Research Article
Perception of Online Lectures among Students of a Medical College in Kathmandu: A Descriptive Cross-sectional StudyOriginal Article Published on 2021-03-312022-10-30 Journal: JNMA: Journal of the Nepal Medical Association [Category] Coronavirus, SARS, [키워드] curriculum medical education online education affected age analysed caused clearance collected college Combination conducted COVID-19 cross-sectional Descriptive statistics effective FIVE form frequencies global pandemic Google Interaction Lecture means Microsoft Excel MOST Online lecture participant percentages Perception positive attitude questionnaire Questionnaires response Sample size similar studies standard deviations student were excluded [DOI] 10.31729/jnma.6276 PMC 바로가기 [Article Type] Original Article
Elevated frequencies of CD14 + HLA-DR lo/neg MDSCs in COVID-19 patientsCOVID-19 환자에서 CD14 + HLA-DR lo/neg MDSC의 빈도 증가Research Paper Published on 2021-03-152022-08-31 Journal: Aging (Albany NY) [Category] MERS, 바이오마커, [키워드] albumin analyzed association B cell CD14 Cell change Clinical characteristics correlated correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 progression COVID-19 severity determined by disease severity elevated evaluate flow cytometry Follow-up Frequency greater HLA-DR Hospital stay hyper-inflammation ICU patient immune responses immunoparalysis Immunosuppression immunosuppressive laboratory data lymphocyte Lymphocyte count lymphocyte counts MDSC Most patients NK cell nucleic acid Oropharyngeal Patient percentage percentages positively correlated Prognosis SARS-CoV-2 SARS-CoV-2 nucleic acid serum albumin severe patients T cell Viral Viral load [DOI] 10.18632/aging.202571 PMC 바로가기 [Article Type] Research Paper
COVID-19 infection control measures and outcomes in urban dialysis centers in predominantly African American communitiesResearch Article Published on 2021-03-062022-10-28 Journal: BMC Nephrology [Category] COVID-19, SARS, [키워드] African American assessment average calculated Care Characteristics Clinical characteristics commenced Community conducted COVID COVID-19 COVID-19 infection COVID-19 patient death diagnosed with COVID-19 dialysis female follow-up period Frame Hospitalization hospitalizations infection control measure median median age MONITOR MOST national guideline outcome Patient patients patients with COVID-19 percentage percentages positive PPE receiving required Result SARS-CoV-2 Spread the patient Transmission Two patient with COVID-19 [DOI] 10.1186/s12882-021-02281-6 PMC 바로가기 [Article Type] Research Article
Laboratory Predictors of COVID-19 Mortality: A Retrospective Analysis from Tongji Hospital in WuhanCOVID-19 사망률의 실험실 예측자: 우한 Tongji 병원의 후향적 분석Research Article Published on 2021-02-232022-09-10 Journal: Mediators of Inflammation [Category] MERS, 바이오마커, [키워드] 95% CI acute respiratory disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis anti-inflammatory cytokine approved carried caused Chinese coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality COVID-19 patient COVID-19 patients cytokine Cytokines Deceased diagnosed with COVID-19 disease effective end product ferritin global pandemic hyperinflammation Hyperuricemia Hypoalbuminemia IL-10 IL-6 inflammatory markers medication metabolism Mortality novel Novel coronavirus objective Patient patients with COVID-19 percentage percentages predictor Prevalence progressed Proinflammatory cytokine proinflammatory cytokines purine recovered patient recovered patients reduction reported respiratory Respiratory disease Result Retrospective analysis risk factor Risk factors SARS-CoV-2 Serum level severe acute respiratory syndrome Coronavirus significant difference significant differences specificity survived therapy TNF- α Tongji Hospital uric acid was increased Wuhan Wuhan, China [DOI] 10.1155/2021/6687412 PMC 바로가기 [Article Type] Research Article
Dealing with the impact of the COVID-19 pandemic on a rapid response team operation in Brazil: Quality in practiceObservational Study Published on 2021-02-202022-10-04 Journal: International journal for quality in health care : [Category] 임상, [키워드] Adequacy adjust adjusted analyzed average Brazil Care carried choice coronavirus disease COVID-19 COVID-19 pandemic Critical Critical care critical care outcomes Critical case Critically ill Effectiveness hospital hospital rapid response team Hospital wards Infection intensive care Intervention laboratory-confirmed lesson maintain Mortality not affected observation pandemic Patient percentages professionals Quality rapid response remained reported RRT study period These data treated treated patient workforce [DOI] 10.1093/intqhc/mzaa114 PMC 바로가기 [Article Type] Observational Study
Seroprevalence of SARS-CoV-2 Antibodies in Children and Adults in St. Louis, Missouri, USA미국 미주리주 세인트루이스의 소아 및 성인에서 SARS-CoV-2 항체의 혈청유병률Research Article Published on 2021-02-032022-09-12 Journal: mSphere [Category] MERS, 진단, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adults age antibodies antibody Asymptomatic case children collected confirmed case confirmed cases coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 credible interval demonstrated ELISAs enzyme-linked immunosorbent assay greater house IgG IgG antibodies IgG antibody individual Infection Mild nucleoprotein Older Patient pediatric percentage percentages positive presenting Prevalence protocol protocols SARS-CoV-2 serology Seropositivity Seroprevalence serum/plasma severe acute respiratory syndrome Coronavirus significantly lower St. Louis tested USA were infected [DOI] 10.1128/mSphere.01207-20 PMC 바로가기 [Article Type] Research Article
The COVID-19 Sequelae: A Cross-Sectional Evaluation of Post-recovery Symptoms and the Need for Rehabilitation of COVID-19 SurvivorsPhysical Medicine & Rehabilitation Published on 2021-02-022022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome age analyzed association Campus Characteristics classification Comorbidities conducted coronavirus disease Coronavirus-2 correlation COVID-19 COVID-19 recovered patients COVID-19 severity cross-sectional determine dimension disease disease severity fatality fatigue FIVE Frequency Gender General population globe healthcare IBM individuals Infection information Karachi long-COVID majority manifestation Manifestations MERS Middle East Mild moderate Occurrence Pandemics participant Participants percentages persistence post-covid-19 symptoms Prevalence prevalent Quality of life Quality of life (QoL) question questionnaire recognize Recovered COVID-19 patients recovery rehabilitation reported Result risk SARS-CoV-2 SARS-COV-2 infection Severe COVID-19 Infection severity significant difference significantly sociodemographic data SPSS Stigma survivor Symptom Symptoms syndrome USA Visual was obtained [DOI] 10.7759/cureus.13080 PMC 바로가기 [Article Type] Physical Medicine & Rehabilitation