Postinfection – Page 5 – Communicable Diseases Research

Cellular tropism of SARS-CoV-2 in the respiratory tract of Syrian hamsters and B6.Cg-Tg(K18-ACE2)2Prlmn/J transgenic mice

Article

Published on 2021-09-012022-10-28
Journal: Veterinary pathology [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS,

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

프로테아제 억제제를 사용한 감염 후 치료는 치명적인 SARS-CoV-2 감염이 있는 생쥐의 생존을 증가시킵니다

Comparative Study

Published on 2021-07-202022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, 신약개발, 진단, 치료제,

[키워드] 3CLpro acute respiratory syndrome acute respiratory syndrome coronavirus ameliorated animal models Antiviral antiviral agent Antiviral agents antiviral drug Antiviral effect assays binding interaction binding interactions causative agent Cell culture change Compound coronavirus COVID-19 develop dose effective Efficacy enzyme evaluated global public health High-resolution histopathological human coronavirus human coronaviruses in vitro assays increase increased survival Infection inhibiting inhibitor inhibitory activity K18-ACE2 mice K18-hACE2 mice lethal infection Lung pathology mice Mild Postinfection potency protease Protease inhibitor protease inhibitors Replication reported respiratory SARS-CoV SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 patient severe COVID-19 patients Significance significantly increased survival therapeutic efficacy therapeutic option transgenic mice treated Treatment variant Viral virus virus replication virus titer virus titers were used
[DOI] 10.1073/pnas.2101555118 PMC 바로가기 [Article Type] Comparative Study

Severe reinfection with severe acute respiratory syndrome coronavirus 2 in a nursing home resident: a case report

요양원 거주자에서 중증급성호흡기증후군 코로나바이러스 2에 의한 중증 재감염: 증례보고

Case Reports

Published on 2021-07-202022-09-10
Journal: Journal of Medical Case Reports [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Case report Cohort studies cohort study convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 Dexamethasone discharged home Dyspnea elevated Encephalopathy Evidence Factor fevers hypoxemic Hypoxemic respiratory failure Immunity indicated Infection inflammatory markers initial intubation lung lung infiltrate lung infiltrates male Mild symptom mild symptoms natural immunity nursing home Patient positive Postinfection provide Reinfection Remdesivir report reported respiratory Respiratory failure SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe disease Symptoms Topic Treatment vaccination
[DOI] 10.1186/s13256-021-02958-4 PMC 바로가기 [Article Type] Case Reports

Longitudinal Serology of SARS-CoV-2-Infected Individuals in India: A Prospective Cohort Study

인도에서 SARS-COV-2- 감염된 개인의 종단 혈청학 : 전향 적 코호트 연구

Articles

Published on 2021-07-182022-09-10
Journal: The American Journal of Tropical Medicine and Hygi [Category] SARS, 진단, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 All participant All participants Antigen Asia Asymptomatic Capital Capital Region Characteristics clinical cohorts comparable convalescence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 epidemiological highlight humoral immune response IgG IgG antibodies IgG antibody immune responses Immunoglobulin Immunoglobulin G immunological characteristics India individual Infection longitudinal Mild mild to moderate moderate multivariable Multivariable regression analysis nasopharyngeal viral nucleocapsid participant positive individuals Postinfection predictor proportion Prospective prospective cohort RBD RBD antigen Receptor binding domain Region regression analysis respiratory response RNA RT-PCR RT-PCR SARS-CoV-2 SARS-CoV-2-positive individual Seroconversion seroconversion rate seroconversion rates serological response serology Seropositivity Serosurveys severe acute respiratory syndrome Coronavirus severe disease severity South subset symptomatic the RBD threshold value Viral were assessed
[DOI] 10.4269/ajtmh.21-0164 PMC 바로가기 [Article Type] Articles

Severe Acute Respiratory Syndrome Coronavirus 2 Infects and Damages the Mature and Immature Olfactory Sensory Neurons of Hamsters

중증 급성 호흡기 증후군 코로나바이러스 2는 햄스터의 성숙하고 미성숙한 후각 감각 뉴런을 감염시키고 손상시킵니다

Article

Published on 2021-07-152022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료기술,

[키워드] Acute inflammation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition affecting Antigen Apoptosis Cell cells chemokine ciliated contribute coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 patient Cytokines damage destruction develop epithelial cells hamster hamsters highest immature Infection Inflammatory inflammatory cell inflammatory cell infiltration Inflammatory cytokine Inflammatory cytokines intranasal Invasion investigated less location Loss of Smell marker nasal nasal turbinate Neuron neuronal function olfactory olfactory bulb olfactory bulbs olfactory dysfunction Olfactory epithelium olfactory neuron olfactory neuron. Pathogenesis patients peaked Postinfection proinflammatory Proinflammatory cytokine proportion Protein reported respiratory respiratory epithelial cells respiratory tract infection response resulting SARS-CoV-2 SARS-CoV-2 viral Sensory sensory neuron severe acute respiratory syndrome Coronavirus Symptom tissues unique Viral load β-tubulin
[DOI] 10.1093/cid/ciaa995 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Transmission Risk Among National Basketball Association Players, Staff, and Vendors Exposed to Individuals With Positive Test Results After COVID-19 Recovery During the 2020 Regular and Postseason

2020 정규 및 포스트 시즌 동안 COVID-19 회복 후 양성 테스트 결과를 보인 개인에게 노출된 NBA 선수, 직원 및 공급업체 간의 SARS-CoV-2 전파 위험

Multicenter Study

Published on 2021-07-012022-09-11
Journal: JAMA Internal Medicine [Category] Fulltext, SARS, 진단, 치료기술,

[키워드] activities activity ad hoc Asymptomatic center Chain Reaction Characteristics clinical Clinical data clinically collected Control COVID-19 COVID-19 case criteria cycle Cycle threshold values disease control event Health IgG antibodies index individual individuals Infection infectious Interaction involved Isolation limit of detection male occupational health outcome participated Participation PCR test PCR testing persistent polymerase chain reaction positive positive individuals positive RT-PCR positive test result Postinfection precautions prevention recommendation Regular remained required Result retrospective cohort study risk Roche RT-PCR RT-PCR test RT-PCR testing SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-COV-2 infection SARS-CoV-2 test Secondary infection secondary infections Serological testing staff Support Test test results threshold value Transmission used data Vendor Viral viral dynamics Viral transmission
[DOI] 10.1001/jamainternmed.2021.2114 PMC 바로가기 [Article Type] Multicenter Study

SARS-CoV-2 Aerosol Exhaled by Experimentally Infected Cynomolgus Monkeys

실험적으로 감염된 Cynomolgus 원숭이가 내뿜는 SARS-CoV-2 에어로졸

Research Letter

Published on 2021-07-012022-09-10
Journal: Emerging Infectious Diseases [Category] SARS, 치료기술,

A SARS-CoV-2 Label-Free Surrogate Virus Neutralization Test and a Longitudinal Study of Antibody Characteristics in COVID-19 Patients

SARS-CoV-2 표지 없는 대리 바이러스 중화 테스트 및 COVID-19 환자의 항체 특성에 대한 종단 연구

Article

Published on 2021-06-182022-09-12
Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단,

[키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 antibody Antibody avidity antibody neutralization activity applicability binding ability Concentration coronavirus coronavirus disease COVID-19 Deterioration determine domain humoral IgG immunoassay include Increases individuals inhibitory concentration initial label-free technology Laboratory longitudinal longitudinal study molecular interaction neutralization Neutralizing neutralizing antibody Neutralizing antibody titer Patient platform post-symptom onset Postinfection RBD reduction in Research SARS-CoV-2 SARS-CoV-2 spike protein serum serum sample surrogate surrogate neutralization virus test. symptom onset Test Variability virus virus neutralization test
[DOI] 10.1128/JCM.00193-21 PMC 바로가기 [Article Type] Article

Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

Dispatch

Published on 2021-05-012022-10-31
Journal: Emerging Infectious Diseases [Category] Coronavirus,

Longitudinal Analysis and Comparison of Six Serological Assays up to Eight Months Post-COVID-19 Diagnosis

Article

Published on 2021-04-212022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,