prospective observational cohort – Page 5 – Communicable Diseases Research

Guillain-Barré syndrome after SARS-CoV-2 infection in an international prospective cohort study

국제 전향 코호트 연구에서 SARS-CoV-2 감염 후 길랭-바레 증후군

Observational Study

Published on 2021-12-162022-09-11
Journal: Brain : a journal of neurology [Category] SARS, 변종, 임상,

Modulatory Effects of Physical Activity Levels on Immune Responses and General Clinical Functions in Adult Patients with Mild to Moderate SARS-CoV-2 Infections—A Protocol for an Observational Prospective Follow-Up Investigation: Fit-COVID-19 Study

Protocol

Published on 2021-12-162022-10-04
Journal: International Journal of Environmental Research an [Category] SARS, 임상,

[키워드] activity Adipose tissue analyzed approach baseline Biochemistry Blood blood sample body composition clinical collected conducted Control coronavirus coronavirus disease COVID-19 cytokine profile determine Effect evaluated Evidence exercise Exercise capacity explain expressed function functional healthy help homologous immune Immunity immunomodulatory in-vitro assay inactive individual Infection Inflammation Inflammatory information innate immune system knowledge Level long-COVID mechanism Mental mental health metabolic parameters metabolism Mild Moderate COVID-19 mononuclear cell obese participant Patient patients with COVID-19 PBMC PBMCs peripheral phenotypic physical physical activity physical activity level physically positive procedure Prospective prospective observational cohort provided Pulmonary function registry repeated-measures ANOVA Respiratory muscle strength respond response SARS-CoV-2 SARS-COV-2 infection Seahorse serum stimulated survival the SARS-CoV-2 virus the vaccine Trajectories treated vaccination venous viral infection virus
[DOI] 10.3390/ijerph182413249 PMC 바로가기 [Article Type] Protocol

Association between coronary artery calcifications and 6-month mortality in hospitalized patients with COVID-19

코로나19로 입원한 환자의 관상동맥 석회화와 6개월 사망률의 연관성

Observational Study

Published on 2021-12-012022-09-11
Journal: Diagnostic and interventional imaging [Category] SARS, 임상, 치료기술,

Endothelium-associated biomarkers mid-regional proadrenomedullin and C-terminal proendothelin-1 have good ability to predict 28-day mortality in critically ill patients with SARS-CoV-2 pneumonia: A prospective cohort study

내피 관련 바이오마커 mid-regional proadrenomedullin 및 C-terminal proendothelin-1은 SARS-CoV-2 폐렴 중환자에서 28일 사망률을 예측하는 우수한 능력을 가지고 있습니다. 전향적 코호트 연구

Observational Study

Published on 2021-12-012022-09-11
Journal: Journal of critical care [Category] SARS, 바이오마커, 임상,

[키워드] 28-day mortality 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus adjusted age AUC baseline Biomarker Biomarkers C-terminal collected coronavirus COVID-19 Critically ill Critically ill patient critically ill patients CT-proET-1 high accuracy identify investigated Mortality MR-proADM MR-proADM. multivariable Cox regression multivariable Cox regression model non-survivor Pneumonia predict predictor prospective cohort study prospective observational cohort remained respiratory ROC Curve ROC curves SARS-CoV-2 SARS-CoV-2 pneumonia Seven severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly higher SOFA score
[DOI] 10.1016/j.jcrc.2021.07.017 PMC 바로가기 [Article Type] Observational Study

Reinfection with new variants of SARS-CoV-2 after natural infection: a prospective observational cohort in 13 care homes in England

Observational Study

Published on 2021-12-012022-10-05
Journal: The Lancet. Healthy longevity [Category] SARS, 변종, 임상, 진단,

[키워드] Alpha Antigen binding Care Concentration COVID-19 vaccination Cox proportional hazard diagnostic Effectiveness eight England FIVE Follow-up follow-up period groups had no individual infected individual infected individuals Kinetics Lateral flow device London national guidelines natural infection Neutralising activity neutralising antibody nose and throat occurred Older participant Poisson regression positive Positive test Primary infection Primary outcome prospective observational cohort protection Protective Public recruited Reinfection required risk RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV-2 spike Serological testing staff Surveillance susceptible individual sustained swab sample symptomatic individuals tested timepoint titre transmissible variants understanding variant variants of SARS-CoV-2 were assessed were used
[DOI] 10.1016/S2666-7568(21)00253-1 PMC 바로가기 [Article Type] Observational Study

Normalized Cardiac Structure and Function in COVID-19 Survivors Late After Recovery

Cardiovascular Medicine

Published on 2021-11-292022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

[키워드] Abnormalities abnormality acute phase Admission Biomarker Blood cardiac cardiac troponin Concentration conducted consequence controls coronavirus disease Coronavirus disease 2019 COVID-19 Critical Diagnosis diastolic echocardiographic Evidence function functional healthy control information IQR mitral Myocardial myocardial injury Myocardial strain N-terminal no significant difference NT-proBNP parameters Patient patients performed pro-B-type natriuretic peptide prospective observational cohort risk septal serum Speckle tracking echocardiography Standard Structure survivor Survivors tested three group troponin ventricular Volume
[DOI] 10.3389/fcvm.2021.756790 PMC 바로가기 [Article Type] Cardiovascular Medicine

Response of patients with acute respiratory failure caused by COVID-19 to awake-prone position outside the intensive care unit based on pulmonary involvement

Observational Study

Published on 2021-11-252022-10-04
Journal: Clinics [Category] MERS, SARS, 임상,

[키워드] 95% confidence interval age analyzed body mass index caused characteristic clinical Clinical outcome Comorbidities conducted COVID-19 COVID-19 patient Critical Care Outcome Cutoff cutoff point effective Endotracheal intubation evaluate hazard ratio hospital hypoxic respiratory failure ICU identify IMPROVE intensive care Intervention laboratory data lung median Mortality non-responder noninvasive respiratory Noninvasive ventilation outcome Oxygenation PaO parenchymal damage Patient patients with COVID-19 positive prevent disease progression Prone position prospective observational cohort pulmonary impairment pulmonary involvement reduce mortality Respiratory failure respiratory insufficiency Responder responders response sensitivity Sensitivity and specificity Sex specificity Support the patient Treatment treatments for COVID-19 ventilatory assistance
[DOI] 10.6061/clinics/2021/e3368 PMC 바로가기 [Article Type] Observational Study

Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity

코로나바이러스 질병 2019(COVID-19) 심각도의 바이러스 역학 및 면역 상관관계

Observational Study

Published on 2021-11-022022-09-12
Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 임상, 진단,

[키워드] age Antibody Response association Characteristics chemokine Clinical severity collected Comorbidities coronavirus 2 correlated COVID-19 Culture Cytokines disease severity Dynamics evaluated HGF IgM IgM and IgG IgM/IgG IL-12p70 IL-18 IL-1ra IL-6 immune markers immune response immune signature immunology Immunotherapy Infection Inflammatory cytokine Invasive mechanical ventilation IP-10 IQR knowledge Level MCP-1 median MIP-1α occurred offer overactive Patient PCR PCR cycle PCR-confirmed plasma sample positive proinflammatory prospective observational cohort Randomized controlled trials required respiratory respiratory sample SARS-CoV-2 SARS-COV-2 infection Seroconversion seroconverted serologic testing serology serum sample severity significantly supplemental oxygen symptom onset target threshold viability viral culture viral dynamics Viral pneumonia virus
[DOI] 10.1093/cid/ciaa1280 PMC 바로가기 [Article Type] Observational Study

Olfactory dysfunction and coronavirus disease 2019 severity: a prospective cohort study

Observational Study

Published on 2021-11-012022-10-05
Journal: The Journal of laryngology and otology [Category] SARS, 임상,

Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study

ChAdOx1 nCoV-19 및 BNT162b2를 사용한 동종 및 이종 프라임-부스트 면역의 안전성, 반응성 및 면역원성: 전향적 코호트 연구

Observational Study

Published on 2021-11-012022-09-11
Journal: The Lancet. Respiratory Medicine [Category] MERS, SARS, 변종, 임상, 진단,

[키워드] 95% CI Alpha anti-RBD Anti-RBD IgG Anti-S1 AstraZeneca B.1.1.7 B.1.351 Berlin Beta Beta variant beta variants binding BNT162b2 boost booster Cambridge ChAdOx1 ChAdOx1 nCoV-19 Concentration COVID-19 COVID-19 vaccines Cutoff dose education enrolled geometric mean Germany health-care Heterologous heterologous prime-boost highest homologous IFN-γ IgG levels immunisation immunogenicity IMPROVE inhibitory interim analysis IQR Mainz median mitigate neutralisation test participant Pfizer-BioNTech prospective cohort study prospective observational cohort pseudovirus neutralisation assay questionnaire RBD IgG RBD-ACE2 reactivity reactogenicity receiving recipient recipients regimen reported Safety SARS-CoV-2 S1 SARS-CoV-2 virus SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody second vaccination specific antibodies supply shortage Symptom systemic systemic symptoms T-cell vaccination Vaccine variants of concern was measured
[DOI] 10.1016/S2213-2600(21)00357-X PMC 바로가기 [Article Type] Observational Study