Effectiveness of Inactivated COVID-19 Vaccines Against Illness Caused by the B.1.617.2 (Delta) Variant During an Outbreak in Guangdong, China : A Cohort Study중국 광둥성 발병 기간 동안 B.1.617.2(델타) 변종으로 인한 질병에 대한 비활성화된 COVID-19 백신의 효과 : 코호트 연구Observational Study Published on 2022-04-012022-09-11 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI adjusted Against age Analysis B.1.617.2 China cohort study COVID-19 COVID-19 vaccine Critical Critical illness Delta development dose doses effective Effectiveness effort Evidence foundation Guangdong illness immunization inactivated Inactivated vaccine Inactivated Vaccines Infection infections laboratory-confirmed natural observational study outbreak outcome participant Participants Patient Pneumonia populations Primary outcome Program reported research and development Result retrospective cohort study Science secondary outcome Secondary outcomes severe or critical illness severity symptomatic infection symptomatic infections vaccination Vaccine variant variant of SARS-CoV-2 [DOI] 10.7326/M21-3509 PMC 바로가기 [Article Type] Observational Study
Convalescent plasma therapy in patients with severe COVID-19, A single-arm, retrospective studyObservational Study Published on 2022-04-012022-10-04 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 바이오마커, 임상, [키워드] Admission age association Blood Group Characteristics Clinical outcome collected conditions conducted convalescent plasma COVID COVID-19 COVID-19 mortality CP therapy death demographic diagnosed dose Effect effective Effectiveness Efficacy evaluate Evidence hospital discharge Inflammatory biomarker Laboratory laboratory parameter median medical record Mortality Older age Other Patient plasma prothrombin randomized clinical trial respiratory retrospective cohort Retrospective study SARS-CoV-2 Secondary outcomes severe COVID-19 Sex significantly single-arm Stage suggested Symptom the disease therapy Treatment Treatment outcome Viral diseases [DOI] 10.1016/j.micpath.2022.105482 PMC 바로가기 [Article Type] Observational Study
Clinical outcomes of monoclonal antibody therapy during a COVID-19 outbreak in a skilled nursing facility-Arizona, 20212021년 애리조나주 전문 요양 시설에서 COVID-19 발생 시 단일 클론 항체 요법의 임상 결과Article Published on 2022-04-012022-09-11 Journal: Journal of the American Geriatrics Society [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] adjusted Administered age association authorization bamlanivimab Care clinical Clinical outcome clinical outcomes Comorbidities Comorbidity COVID-19 COVID-19 disease COVID-19 mortality COVID-19 outbreak COVID-19 pandemic determine Effectiveness eligibility eligible Emergency Escalation EUA FDA group Immunotherapy IMPROVE increased risk information Logistic regression mAb medical record medical records Mild-to-moderate monoclonal antibody monoclonal antibody therapy morbidity and mortality Mortality multivariable logistic regression not significantly different outbreak outcome Outpatient oxygen Oxygen requirements Oxygen therapy receive reduced Referral resident SARS-COV-2 infection SARS-CoV-2 variant secondary Secondary outcomes severe COVID-19 disease Skilled nursing facilities therapy treated Treatment was used with COVID-19 [DOI] 10.1111/jgs.17705 PMC 바로가기 [Article Type] Article
Early prediction of COVID-19-associated acute kidney injury: Are serum NGAL and serum Cystatin C levels better than serum creatinine?COVID-19 관련 급성 신장 손상의 조기 예측: 혈청 NGAL 및 혈청 시스타틴 C 수치가 혈청 크레아티닌보다 나은가요?Article Published on 2022-04-012022-09-11 Journal: Clinical biochemistry [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] acute kidney Acute kidney injury Admission AKI AUC Biomarker Biomarkers clinical settings comparable coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patients creatinine cystatin C demonstrated Diagnosis diagnostic disease severity elevated emergency department etiologies high risk ICU ICU admission intensive care intensive care unit Intervention kidney Kidney injury Laboratory medicine laboratory-confirmed Laboratory-confirmed COVID-19 Mortality neutrophil predictor presenting Primary outcome renal replacement therapy replacement therapy risk stratification RRT SARS-CoV-2 secondary outcome Secondary outcomes sensitivity serum serum creatinine shown suggested utility while [DOI] 10.1016/j.clinbiochem.2022.01.006 PMC 바로가기 [Article Type] Article
Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: a test-negative, case-control study and a mechanistic study of post-vaccination immune responses인도 델타(B.1.617.2) 변이형 급증 시 SARS-CoV-2 감염에 대한 ChAdOx1 nCoV-19 백신의 효과: 테스트 음성, 사례 대조군 연구 및 백신 접종 후 면역 반응에 대한 기계론적 연구Article Published on 2022-04-012022-09-11 Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] 95% CI addition adjusted Alpha antibody Antigen B.1.1.7 B.1.351 B.1.617.1 B.1.617.2 Beta Biotechnology case-control study CD4 CD8 T-cell response CD8 T-cell responses cellular Cellular immune response ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine Complete conserved Control Council COVID-19 COVID-19 vaccine delta variant Department disease effective Effectiveness geometric mean geometric mean titre healthy Humoral immunity immune protection immune response immune responses In-vitro India individual Industrial infected individuals laboratory-confirmed SARS-CoV-2 infection Mild Mild disease moderate-to-severe COVID-19 negative RT-PCR neutralisation neutralising antibody neutralising antibody response Neutralising antibody responses participant PCR test positive RT-PCR Primary outcome recipient remained Research RT-PCR test SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants secondary outcome Secondary outcomes single dose Spike protein Spike-specific T-cell responses T-cell immune response T-cell immune responses T-cell Response tested the spike protein vaccinated individuals vaccination Vaccine variant variant of SARS-CoV-2 variants VoC VOCs wild-type SARS-CoV-2 with mild disease [DOI] 10.1016/S1473-3099(21)00680-0 PMC 바로가기 [Article Type] Article
Effects of tai chi and qigong on rehabilitation after COVID-19: a protocol for systematic review and meta-analysisCovid-19 이후의 재활에 대한 태극권과 Qigong의 영향 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2022-03-252022-08-31 Journal: BMJ Open [Category] MERS, meta-analysis, [키워드] adverse events Analysis article assessment assessment tool benefit Bia China Chinese Cochrane Library collected complications conducted Consent COVID-19 cure rate database Effect Efficacy and safety Ethical approval Ethics evaluate expiratory forced expiratory volume forced vital capacity guideline heterogeneity high mortality inception incidence include International item journal life literature Meta-analysis Mortality network outcome oxygen oxygen saturation peer-reviewed performed Primary outcome Primary outcomes PROSPERO protocol public health public health emergency Qigong Quality of life registration number rehabilitation rehabilitation medicine Remission reported Reporting review screened secondary Secondary outcomes sensitivity analysis shown statistical analyses subject subject terms Symptoms systematic review systematic reviews Tai Chi Transmission vital capacity Volume Web of Science white cell widespread [DOI] 10.1136/bmjopen-2021-059067 PMC 바로가기 [Article Type] Article
Behavioural Activation for Social IsoLation (BASIL+) trial (Behavioural activation to mitigate depression and loneliness among older people with long-term conditions): Protocol for a fully-powered pragmatic randomised controlled trialBASIL+(사회적 고립을 위한 행동 활성화) 시험(장기 조건을 가진 노인의 우울증과 외로움을 완화하기 위한 행동 활성화): 완전한 실용주의 무작위 통제 시험을 위한 프로토콜Article Published on 2022-03-242022-09-11 Journal: PLoS ONE [Category] 임상, [키워드] 1:1 acceptability Activation Adults Anxiety BASIL build Care clinical clinically ClinicalTrials collected conducted consequence Control Controlled trial COVID-19 COVID-19 pandemic Depression depressive symptom Depressive symptoms eight eligible England evaluate evaluated for inclusion Health health problem Health Service include increased risk information Intervention Isolation life loneliness Long-term condition long-term conditions Mental mental health mitigate Older outcome parallel-group participant Participants physical physically Pragmatic Primary outcome Psychological intervention Quality of life questionnaire randomisation randomised controlled trial receive recruited Registered Research scored secondary Secondary outcomes self-help social isolation stratified Support supported Trial Two-arm usual care worker [DOI] 10.1371/journal.pone.0263856 PMC 바로가기 [Article Type] Article
Role of Telemedicine in Inflammatory Bowel Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials염증성 장 질환에서 원격 진료의 역할: 무작위 대조 시험의 체계적인 검토 및 메타 분석Review Published on 2022-03-242022-09-11 Journal: Journal of Medical Internet Research [Category] 임상, [키워드] 95% CI abstracts Analysis benefit bowel Case report case reports Cochrane Library Controlled Controlled trial COVID-19 Data analysis database Depression disease Disease activity Effectiveness Efficiency groups IBD identify Inflammatory Inflammatory bowel disease Intervention Laboratory life management mean difference medication Meta-analysis mobile phone no significant difference no significant differences outcome pandemic Participants Patient Patient satisfaction Primary outcomes Psychological Quality of life Randomized controlled trial Randomized controlled trials Research review role searched Secondary outcomes Self-efficacy significantly higher significantly lower standard care standard care group Stata subgroup analysis systematic review Telemedicine Web of Science were assessed were excluded were used [DOI] 10.2196/28978 PMC 바로가기 [Article Type] Review
Ivermectin for the Treatment of Coronavirus Disease 2019: A Systematic Review and Meta-analysis of Randomized Controlled Trials코로나바이러스 질병 2019 치료를 위한 이버멕틴: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-03-232022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] 임상, [키워드] 95% confidence interval Adult patients adverse event adverse events AEs all-cause mortality all-cause mortality rate all-cause mortality rates benefit Bia confidence interval Control control group control groups Controlled coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 disease severity did not reduce Effect evaluated Evidence Hospital stay inverse Ivermectin LOS main analyses mean difference meta-analyses Meta-analysis Mild moderate Mortality mortality rates outcome outcomes Patient patients with COVID-19 performed Placebo Primary outcomes random effect Randomized controlled trial Randomized controlled trials RCT RCTs reduced Relative risk review risk risk of bia RoB SAE SAEs SARS-CoV-2 searched secondary Secondary outcomes severe AE severe AEs severity of COVID-19 Standard of care subgroups treat viral clearance [DOI] 10.1093/cid/ciab591 PMC 바로가기 [Article Type] Meta-Analysis
Effectiveness of an adapted diving mask (Owner mask) for non-invasive ventilation in the COVID-19 pandemic scenario: study protocol for a randomized clinical trialCOVID-19 대유행 시나리오에서 비침습적 환기를 위한 적응형 잠수 마스크(소유자 마스크)의 효과: 무작위 임상 시험을 위한 연구 프로토콜Article Published on 2022-03-182022-09-11 Journal: Trials [Category] Coronavirus, SARS, 임상, [키워드] adverse effects aerosol aerosolization Anthropometric data Behavior cause causes clinical Clinical sign Clinical signs clinical trial clinical trials Comfort confirmation Contagion Controlled trial COVID COVID-19 COVID-19 pandemic Effectiveness Face mask Follow-up group Health high risk Hospital stay Hospitalization IMPROVE in-hospital mortality include indicated initial Innovation intensive care intensive care unit intubation invasive ventilation Mask Mortality NIV non-invasive ventilation orotracheal intubation oxygen Oxygen therapy PaO Patient patients Primary outcome professionals Randomized randomized clinical trial reduce registry resource respiratory Respiratory failure SARS-CoV2 Satisfaction secondary outcome Secondary outcomes shown Sociodemographic Study protocol submitted suspicion the patient tracheal tracheal intubation variable Ventilation ventilatory virus with COVID-19 [DOI] 10.1186/s13063-022-06133-y PMC 바로가기 [Article Type] Article