A Single-Round Infection Fluorescent SARS-CoV-2 Neutralization Test for COVID-19 Serological Testing at a Biosafety Level-2 LaboratoryBiosafety Level-2 실험실에서 COVID-19 혈청학적 테스트를 위한 단일 라운드 감염 형광 SARS-CoV-2 중화 테스트Article Published on 2022-06-022022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Accuracy Antibody Response Antiviral biosafety BSL-2 BSL-2 laboratory BSL-3 facilities correlated COVID-19 COVID-19 patient evaluated fluorescent gold standard Infection lab Laboratory Large-scale testing linearity live viruses natural infection neutralization Neutralization assay neutralizing antibody Neutralizing titer plaque reduction neutralization plasma PRNT R 2 reproducibility robust SARS-CoV-2 SARS-CoV-2 virus sensitivity Sensitivity and specificity serological test serum single-round infection fluorescent SARS-CoV-2 virus specificity specimens Test Testing vaccination [DOI] 10.3390/v14061211 PMC 바로가기 [Article Type] Article
Humoral immune response after COVID-19 infection or BNT162b2 vaccine among older adults: evolution over time and protective thresholds노년층에서 COVID-19 감염 또는 BNT162b2 백신 후 체액성 면역 반응: 시간 경과에 따른 진화 및 보호 역치Article Published on 2022-06-012022-09-12 Journal: GeroScience [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] age Anti-RBD IgG Antibody titer BNT162b2 vaccine COVID-19 COVID-19 infection decrease Dynamics Evolution first vaccination immune response Infection injection IQR Kinetics less maintain natural infection Older Patient patients with SARS-CoV-2 Protective SARS-CoV-2 serological test serology significantly higher Support symptom onset the median the SARS-CoV-2 the vaccine three groups threshold vaccination Vaccine vaccine group [DOI] 10.1007/s11357-022-00546-y PMC 바로가기 [Article Type] Article
Exposure factors associated with SARS-CoV-2 seroprevalence during the first eight months of the COVID-19 pandemic in the Netherlands: A cross-sectional study네덜란드에서 COVID-19 대유행의 첫 8개월 동안 SARS-CoV-2 혈청 유병률과 관련된 노출 요인: 단면 연구Article Published on 2022-05-122022-09-12 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] absence accelerate activities activity association average behavioural Contact COVID-19 COVID-19 pandemic cross-sectional cumulative defined determine driver eight eligible evaluate exposure Factor Factors healthcare Infection initial majority mapped multivariable logistic regression Netherlands Numerous overcome pandemic participant Participants questionnaire reached reflected respiratory risk SARS-CoV-2 SARS-CoV-2 seroprevalence serological test Seropositivity social distancing Spain univariable variety virus spread was determined women [DOI] 10.1371/journal.pone.0268057 PMC 바로가기 [Article Type] Article
Hospital-wide SARS-CoV-2 antibody screening of 4840 staff members in a University Medical Center in France: a cross-sectional study프랑스 대학의료원 직원 4840명을 대상으로 한 병원 차원의 SARS-CoV-2 항체 스크리닝: 단면 연구Article Published on 2022-05-112022-09-12 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI age Ageusia analysed Analysis Anosmia assistant center contact with COVID-19 cross-sectional Fever France headache Healthcare professional healthcare professionals healthcare worker hospital industrial medicine infected with SARS-CoV-2 Infection infection control infectious risk myalgia occupational & Predictive professional proportion public health questionnaire SARS-CoV-2 SARS-CoV-2 antibody secondary outcome serological test Sex significantly significantly higher Sociodemographic Symptom Symptoms university variable Virology [DOI] 10.1136/bmjopen-2020-047010 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 Nucleocapsid, Spike, and Neutralizing Antibodies in Vaccinated Japanese백신을 접종한 일본인에서 SARS-CoV-2 뉴클레오캡시드, 스파이크 및 중화 항체 검출Article Published on 2022-05-052022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody Antibody titers coronavirus correlated detection detection system Efficacy Efficiency Elecsy Elecsys evaluate evaluated Fujirebio healthy subject healthy subjects IgG investigated Japanese Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers nucleocapsid patients with COVID-19 respiratory Roche SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 N sensitivity sera serological test severe acute respiratory syndrome Coronavirus specificity spike vaccination were assessed [DOI] 10.3390/v14050965 PMC 바로가기 [Article Type] Article
Systematic assessment of the humoral response against SARS-CoV-2 in a French cohort of 283 patients with rheumatic diseases류마티스 질환이 있는 283명의 프랑스 코호트에서 SARS-CoV-2에 대한 체액 반응의 체계적인 평가Article Published on 2022-05-012022-09-11 Journal: Joint bone spine [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] anti-S Arthritis Asymptomatic Cohort COVID-19 Descriptive analyses Descriptive analysis detect diagnosis of COVID-19 diagnosis of SARS-CoV-2 DMARDs form French humoral IgG infected patients Infection infliximab nucleocapsid protein outpatient clinic Paris Patient patients performed proportion Protein rheumatic disease Rheumatic diseases Rheumatoid rheumatoid arthritis rituximab RTX SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections screened serological test serology Seroprevalence significant difference Spike protein spondyloarthritis symptomatic the SARS-CoV-2 the Spike [DOI] 10.1016/j.jbspin.2021.105312 PMC 바로가기 [Article Type] Article
Validation of a quantitative lateral flow immunoassay (LFIA)-based point-of-care (POC) rapid test for SARS-CoV-2 neutralizing antibodiesSARS-CoV-2 중화 항체에 대한 정량적 측면 유동 면역 분석(LFIA) 기반 현장 진료(POC) 신속 검사 검증Article Published on 2022-05-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] analyzed antibody characteristic chemiluminescence immunoassay CLIA collected coronavirus coronavirus disease Coronavirus disease 2019 correlation correlation coefficient COVID-19 detect domain Effectiveness Efficacy evaluate evaluated Good Immunity Kruskal-Wallis test lateral flow immunoassay LFIA Mann-Whitney test Mindray NAbs Neutralizing antibodies no significant differences patients POC point-of-care Quantitative quantitative measurement Rapid test reading receiver operating characteristic respiratory respiratory syndrome coronavirus respiratory syndrome coronavirus 2 ROC SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody sensitivity serological test severe respiratory syndrome significant differences Spike protein stability statistically the spike protein two group two groups Vaccine Vaccines validation widespread [DOI] 10.1007/s00705-022-05422-w PMC 바로가기 [Article Type] Article
Exploratory assessment of serological tests to determine antibody titer against SARS-CoV-2: Appropriateness and limitsSARS-CoV-2에 대한 항체가를 결정하기 위한 혈청학적 검사의 탐색적 평가: 적절성 및 한계Multicenter Study Published on 2022-05-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Analysis analyzed antibody Antibody titer Antibody titers appropriateness can be used Definition detect determine diagnostic diagnostic test diagnostic tests effective Effectiveness Elecsy Elecsys evaluated Health highlight IgA immunoassay Immunoglobulin immunoglobulins Infection International international standard International standards laboratory data limit limitation Luminex xMAP multicenter multiplex Multiplex assay multiplicity RBD resulting Roche S1 domain SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 test SARS-CoV-2 tests selected serological serological test Serological tests serum serum sample serum samples Siemen Spike protein Standard subject subjects the SARS-CoV-2 the WHO titer to define vaccination Variability WHO [DOI] 10.1002/jcla.24363 PMC 바로가기 [Article Type] Multicenter Study
Analysis of Clinical Course and Vaccination Influence on Serological Response in COVID-19 Convalescents코로나19 회복기의 임상 경과 및 백신 접종이 혈청 반응에 미치는 영향 분석Article Published on 2022-04-272022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute phase Analysis anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies antibody Blood clinical clinical and laboratory parameters concerning convalescent correlation correlations COVID-19 COVID-19 infection COVID-19 patient detection DiaSorin disease severity Gender Hospitalization Hospitalized IgG antibodies IgG test immune response Immunological response Infection Inflammation Inflammatory inflammatory parameters influence information Italy knowledge laboratory parameter Laboratory tests LIAISON lung observé parameter Patient patients response S1/S2 SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody serological serological test Serological tests serology severe COVID-19 severity Sex Significant significant difference significant differences significant increase significantly higher subgroup analysis symptomatic patient Symptomatic patients the disease the patient vaccination was performed [DOI] 10.1128/spectrum.02485-21 PMC 바로가기 [Article Type] Article
A prospective study of asymptomatic SARS-CoV-2 infection among individuals involved in academic research under limited operations during the COVID-19 pandemicCOVID-19 대유행 기간 동안 제한된 운영 하에서 학술 연구에 참여하는 개인 중 무증상 SARS-CoV-2 감염에 대한 전향적 연구Article Published on 2022-04-252022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] 95% CI 95% confidence interval acute infections Analysis Antigen Asymptomatic asymptomatic individual Asymptomatic individuals asymptomatic infection baseline Campus conducted COVID-19 COVID-19 pandemic cumulative cumulative incidence detect estimates Future house imperative incidence individual Infection inverse involved Kaplan-Meier estimator longitudinal study MONITOR NTD nucleocapsid pandemic performed platform Population positive RT-PCR Prevalence Prospective Study provided questionnaire Questionnaires RBD repeated required Research risk Risk factors RT-PCR testing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 seroprevalence Seroconversion serological test Serological testing Serological tests serology seropositive Serosurvey spike subclinical infection the Spike Transmission university [DOI] 10.1371/journal.pone.0267353 PMC 바로가기 [Article Type] Article